8-Methyl-1,2,3,4-tetrahydroquinoline
- Product Name
- 8-Methyl-1,2,3,4-tetrahydroquinoline
- CAS No.
- 52601-70-4
- Chemical Name
- 8-Methyl-1,2,3,4-tetrahydroquinoline
- Synonyms
- AKOS BB-9798;AKOS B016010;ART-CHEM-BB B016010;8-METHYL-1,2,3,4-TETRAHYDROQUINOLINE;Quinoline, 1,2,3,4-tetrahydro-8-methyl-;8-Methyl-1,2,3,4-tetrahydroquinoline 98%
- CBNumber
- CB0386407
- Molecular Formula
- C10H13N
- Formula Weight
- 147.22
- MOL File
- 52601-70-4.mol
8-Methyl-1,2,3,4-tetrahydroquinoline Property
- Boiling point:
- 255 °C
- Density
- 0.990±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- liquid
- pka
- 5.01±0.20(Predicted)
- color
- Light brown
- CAS DataBase Reference
- 52601-70-4
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38-22
- Safety Statements
- 26-36/37/39-24/25
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B485988
- Product name
- 8-Methyl-1,2,3,4-tetrahydroquinoline
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- P000622297
- Product name
- 8-Methyl-1,2,3,4-tetrahydroquinoline
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- OR21112
- Product name
- 8-Methyl-1,2,3,4-tetrahydroquinoline
- Purity
- 98%
- Packaging
- 1g
- Price
- $101
- Updated
- 2021/12/16
- Product number
- 3H31-1-53
- Product name
- 8-Methyl-1,2,3,4-tetrahydroquinoline
- Purity
- 98%
- Packaging
- 1g
- Price
- $111
- Updated
- 2021/12/16
- Product number
- X7068
- Product name
- 8-Methyl-1,2,3,4-tetrahydroquinoline
- Packaging
- 1g
- Price
- $117
- Updated
- 2021/12/16
8-Methyl-1,2,3,4-tetrahydroquinoline Chemical Properties,Usage,Production
Uses
8-Methyl-1,2,3,4-tetrahydroquinoline is a useful reagent for template-directed meta-C-H activation.
Definition
ChEBI: 8-Methyl-1,2,3,4-tetrahydroquinoline is a member of quinolines.
Synthesis Reference(s)
The Journal of Organic Chemistry, 25, p. 463, 1960 DOI: 10.1021/jo01073a611
Synthesis
611-32-5
52601-70-4
The general procedure for the synthesis of 8-methyl-1,2,3,4-tetrahydroquinoline from 8-methylquinoline is as follows: unlike the Suzuki-Miyaura coupling reaction, the Pd-pol catalyst exhibits truly non-homogeneous catalytic properties for the reduction of nitroaromatics in the aqueous phase (see Table 2) [46]. In addition, the catalyst can be used for the selective hydrogenation of quinoline derivatives in aqueous-phase media at a pressure of 10 bar H2 at a reaction temperature of 80 °C (cf. Table 3) [47] or at 60 °C with NaBH4 as a hydrogen source (cf. Table 4) [48].
References
[1] Molecules, 2015, vol. 20, # 10, p. 18661 - 18684
[2] Advanced Synthesis and Catalysis, 2017, vol. 359, # 6, p. 933 - 940
[3] Chemical Communications, 2013, vol. 49, # 63, p. 7052 - 7054
[4] Advanced Synthesis and Catalysis, 2016, vol. 358, # 19, p. 3039 - 3045
[5] Patent: CN106831565, 2017, A. Location in patent: Paragraph 0079; 0080; 0081; 0082
8-Methyl-1,2,3,4-tetrahydroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 8-Methyl-1,2,3,4-tetrahydroquinoline manufacturers
- Product
- 8-Methyl-1,2,3,4-tetrahydroquinoline 52601-70-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-14
- Product
- 8-Methyl-1,2,3,4-tetrahydroquinoline 52601-70-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 8-Methyl-1,2,3,4-tetrahydroquinoline 52601-70-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09