Coumarin 106

Product Name: Coumarin 106
CAS No.: 41175-45-5
Chemical Name: Coumarin 106
Synonyms: COUMARIN 478;COUMARIN 106;11-hexahydro-;Exciton Coumarin 478;Coumarin106,lasergrade;Coumarin 106Coumarin 478;Coumarin 106,pure,laser grade;COUMARIN 106, LASER GRADE, PURE;1h,5h-cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9h)-one,2,3,6,7,10,;2,3,5,6,7,9,10,11-octahydrocyclopenta[4,5]pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-12(1H)-one
CBNumber: CB6178790
Molecular Formula: C18H19NO2
Formula Weight: 281.35
MOL File: 41175-45-5.mol

More

Less

Coumarin 106 Property

Melting point:: 149 °C
Boiling point:: 538.4±50.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
solubility: DMSO: Slightly soluble: 0.1-1 mg/ml
pka: 6.38±0.20(Predicted)
form: powder to crystal
color: Light orange to Yellow to Green
λmax: 375nm(Acetone)(lit.)
EPA Substance Registry System: 1H,5H-Cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9H)-one, 2,3,6,7,10,11-hexahydro- (41175-45-5)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 37/39-26
HS Code: 29322985

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: C3043
Product name: Coumarin 478
Purity: >98.0%(HPLC)
Packaging: 200mg
Price: $184
Updated: 2025/07/31

TRC

Product number: C755558
Product name: Coumarin 478
Packaging: 2.5mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC150860
Product name: Coumarin106
Packaging: 100mg
Price: $67
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC150860
Product name: Coumarin106
Packaging: 250mg
Price: $132.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC150860
Product name: Coumarin106
Packaging: 500mg
Price: $230
Updated: 2021/12/16

More

Less

Coumarin 106 Chemical Properties,Usage,Production

Description

Coumarin 478 is a vital chemical compound used in biomedicine mainly for its anticancer properties. It has demonstrated potential in inhibiting tumor growth and metastasis, making it a valuable drug in the treatment of various types of cancers. Coumarin 478 shows promising results in clinical trials and is actively being researched for its effectiveness against specific cancer types.

Chemical Properties

yellow powder and chunks

Uses

Coumarin 106 (Coumarin 478) is a dipolar laser dye. Coumarin 106 is an inhibitor of AChE and BChE. Coumarin 106 displays mixed-type AChE inhibition with a pIC50=4.97 and Ki=2.36 μM. Coumarin 106 inhibits BChE with slightly lower potency (pIC50=4.56)[1][2].

References

[1] Patil SK, et al. Determination of ground and excited state dipole moments of dipolar laser dyes by solvatochromic shift method. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 5;123:117-26. DOI:10.1016/j.saa.2013.12.031
[2] Fallarero A, et al. Inhibition of acetylcholinesterase by coumarins: the case of coumarin 106. Pharmacol Res. 2008 Sep-Oct;58(3-4):215-21. DOI:10.1016/j.phrs.2008.08.001
[3] G.A. REYNOLDS K. H D. New coumarin dyes with rigidized structure for flashlamp-pumped dye lasers[J]. Optics Communications, 1975, 13 3: Pages 222-225. DOI: 10.1016/0030-4018(75)90085-1
[4] EMMA ALEXANDER. Room temperature phosphorescence of coumarin 106 with direct triplet state excitation[J]. Dyes and Pigments, 2023, 217: Article 111389. DOI: 10.1016/j.dyepig.2023.111389

Coumarin 106 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Coumarin 106 Suppliers

Americas 1 Belgium 1 China 34 Europe 1 Germany 2 India 1 Japan 2 South Korea 1 United Kingdom 3 United States 11 Global 57

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

WuHan Taiyukaishang Chemical Co., Ltd.

Tel: 027-027-87680032 18963957250
Email: taiyuchem@163.com
Country: China
ProdList: 180
Advantage: 55

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9979
Advantage: 58

Tianjin Being Technology Co., Ltd.

Tel: 18622939839
Fax: QQ:343281693
Email: tjby921@163.com
Country: China
ProdList: 884
Advantage: 55

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9274
Advantage: 55

More

Less

View Lastest Price from Coumarin 106 manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Coumarin 106 41175-45-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-03-07

41175-45-5, Coumarin 106Related Search:

Dihydrocoumarin DICUMAROL 4-Methylumbelliferone Coumarin 6-Methylcoumarin Coumarin 102 Coumarin 6 Coumarin-3-carboxylic acid Exciton Coumarin 498 Coumarin 337 Coumarin 153 2,3,5,6-1H,4H-Tetrahydro-9-(3-pyridyl)quinolizino[9,9a,1-gh]coumarin Exciton Coumarin 545 Coumarin 521T 1-PHENYLCYCLOPENTENE 4-PENTYLANILINE 7-Dimethylamino-4-methylcoumarin Coumarin 2

11-hexahydro-

1h,5h-cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9h)-one,2,3,6,7,10,

COUMARIN 106

COUMARIN 478

Coumarin106,lasergrade

Exciton Coumarin 478

COUMARIN 106, LASER GRADE, PURE

Coumarin 106,pure,laser grade

Coumarin 106Coumarin 478

2,3,6,7,10,11-HEXAHYDRO-1H,5H-CYCLOPENTA[3,4][1] BENZOPYRANO[6,7,8-IJ]QUINOLIZIN-12(9H)-ONE

2,3,5,6,7,9,10,11-octahydrocyclopenta[4,5]pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-12(1H)-one

1H,5H-Cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9H)-one, 2,3,6,7,10,11-hexahydro-

2,3,6,7,10,11-Hexahydro-1H,5H-cyclopenta[4,5]pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-12(9H)-one

41175-45-5