4-ETHOXYBENZYL ALCOHOL
- Product Name
- 4-ETHOXYBENZYL ALCOHOL
- CAS No.
- 6214-44-4
- Chemical Name
- 4-ETHOXYBENZYL ALCOHOL
- Synonyms
- NSC 406713;RARECHEM AL BD 0088;4-Ethoxybenzyl Acohol;P-ETHOXYBENZYL ALCOHOL;4-ETHOXYBENZYL ALCOHOL;(4-Ethoxyphenyl)methanol;4-Ethoxybenzyl alcohol,98%;4-Ethoxybenzene-1-methanol;Benzenemethanol, 4-ethoxy-;4-Ethoxybenzyl alcohol 98%
- CBNumber
- CB0392578
- Molecular Formula
- C9H12O2
- Formula Weight
- 152.19
- MOL File
- 6214-44-4.mol
4-ETHOXYBENZYL ALCOHOL Property
- Melting point:
- 32-34 °C(lit.)
- Boiling point:
- 273 °C(lit.)
- Density
- 1.0505 (rough estimate)
- refractive index
- n20/D 1.535(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Solubility in methanol is almost transparent.
- pka
- 14.54±0.10(Predicted)
- form
- powder to lump to clear liquid
- color
- White or Colorless to Light yellow
- CAS DataBase Reference
- 6214-44-4(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29094990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E0492
- Product name
- 4-Ethoxybenzyl Alcohol
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $278
- Updated
- 2025/07/31
- Product number
- E891340
- Product name
- 4-EthoxybenzylAcohol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- E891340
- Product name
- 4-EthoxybenzylAcohol
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- J54892
- Product name
- 4-Ethoxybenzyl Alcohol
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 8144AJ
- Product name
- 4-Ethoxybenzyl Alcohol
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
4-ETHOXYBENZYL ALCOHOL Chemical Properties,Usage,Production
Chemical Properties
WHITE TO SLIGHTLY YELLOW CRYST. LOW MELTING MASS
Uses
It is used in the identification of sulfation sites of metabolites and prediction of the compounds? biological effects and in chemical investigation of Wedelia calendulacea.
Synthesis
10031-82-0
6214-44-4
General procedure for the synthesis of p-ethoxybenzyl alcohol from 4-ethoxybenzaldehyde: NaBH4 (0.8 g, 21.7 mmol) was added in batches to a stirring solution of 4-ethoxybenzaldehyde (3.0 g, 19.7 mmol) in methanol (50 mL) at 0 °C, and the addition process lasted for 15 minutes. After the addition, the reaction mixture was continued to be stirred at room temperature for 30 min. After completion of the reaction, the solvent was removed by rotary evaporator to obtain the crude product. The crude product was dissolved in water and extracted twice with ethyl acetate (EtOAc). The organic phases were combined, washed sequentially with water and saturated saline, and dried over anhydrous sodium sulfate. The dried organic phase was concentrated under reduced pressure to give a white solid product, p-ethoxybenzyl alcohol, in 82% yield. The product was analyzed by LC-MS showing [M+H]+ peak of 135.2. 1H-NMR (400 MHz, CDCl3) δ 7.266-7.286 (d, 2H, J = 8.0 Hz), 6.872-6.893 (d, 2H, J = 8.4 Hz), 4.609 (s, 2H), 4.010-4.061 (q, 2H, J = 6.8 Hz), 1.396-1.430 (t, 3H, J = 6.8 Hz).
References
[1] Advanced Synthesis and Catalysis, 2016, vol. 358, # 10, p. 1694 - 1698
[2] Patent: WO2010/127208, 2010, A1. Location in patent: Page/Page column 62
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 12, p. 4861 - 4868
[4] Justus Liebigs Annalen der Chemie, 1933, vol. 507, p. 1,9
[5] Journal of the Chemical Society, 1956, p. 2455,246
4-ETHOXYBENZYL ALCOHOL Preparation Products And Raw materials
Raw materials
Preparation Products
4-ETHOXYBENZYL ALCOHOL Suppliers
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View Lastest Price from 4-ETHOXYBENZYL ALCOHOL manufacturers
- Product
- 4-ETHOXYBENZYL ALCOHOL 6214-44-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2025-08-22
- Product
- 4-ETHOXYBENZYL ALCOHOL 6214-44-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11