4-FLUORO-3-METHOXYBENZOIC ACID
- Product Name
- 4-FLUORO-3-METHOXYBENZOIC ACID
- CAS No.
- 82846-18-2
- Chemical Name
- 4-FLUORO-3-METHOXYBENZOIC ACID
- Synonyms
- BUTTPARK 14\01-28;RARECHEM AL BO 0973;4-fluoro-m-anisic acid;4-Fluoro-3-methoxybenzoic;Fluoro-3-methoxy-benzoic acid;4-FLUORO-3-METHOXYBENZOIC ACID;3-METHOXY-4-FLUOROBENZOIC ACID;4-Fluoro-3-methoxybenzoicAcid>Benzoic acid, 4-fluoro-3-methoxy-;4-Fluoro-m-anisic acid, 5-Carboxy-2-fluoroanisole
- CBNumber
- CB0396031
- Molecular Formula
- C8H7FO3
- Formula Weight
- 170.14
- MOL File
- 82846-18-2.mol
4-FLUORO-3-METHOXYBENZOIC ACID Property
- Melting point:
- 206 °C
- Boiling point:
- 304.8±22.0 °C(Predicted)
- Density
- 1.307±0.06 g/cm3(Predicted)
- Flash point:
- >110℃
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 4.02±0.10(Predicted)
- color
- White to Yellow to Orange
- BRN
- 4178071
- InChIKey
- LWGCZCMLPRMKIZ-UHFFFAOYSA-N
- CAS DataBase Reference
- 82846-18-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-36:37/38-22
- Safety Statements
- 26-36-37
- Hazard Note
- Irritant
- HS Code
- 29189900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F0681
- Product name
- 4-Fluoro-3-methoxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $33
- Updated
- 2025/07/31
- Product number
- F0681
- Product name
- 4-Fluoro-3-methoxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $159
- Updated
- 2025/07/31
- Product number
- F595833
- Product name
- 4-Fluoro-3-methoxybenzoic Acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- F595833
- Product name
- 4-Fluoro-3-methoxybenzoic Acid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 002361
- Product name
- 4-Fluoro-3-methoxybenzoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $9
- Updated
- 2021/12/16
4-FLUORO-3-METHOXYBENZOIC ACID Chemical Properties,Usage,Production
Chemical Properties
White to light yellow crystal powder
Synthesis Reference(s)
Journal of Medicinal Chemistry, 33, p. 2408, 1990 DOI: 10.1021/jm00171a014
Synthesis
74385-37-8
82846-18-2
The general procedure for the synthesis of 3-methoxy-4-fluorobenzoic acid from methyl 4-fluoro-3-methoxybenzoate was as follows: methyl 4-fluoro-3-methoxybenzoate (11 g, 59.8 mmol) was dissolved in methanol (100 mL), and a solution of sodium hydroxide (9.5 g, 240 mmol) in water (20 mL) was added, and the reaction was stirred for 4 h at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to give a residue. The residue was dissolved in water (100 mL) and the pH was adjusted with 1N HCl solution to 4. Subsequently, the precipitated solid was collected by filtration, washed with water (3 x 50 mL), and dried to give 3-methoxy-4-fluorobenzoic acid as a white solid (9 g, 97% yield). The product was characterized by 1H-NMR (300 MHz, DMSO-d6): δ 7.66-7.55 (m, 2H), 7.37-7.30 (m, 1H), 3.91 (s, 3H).
References
[1] Patent: WO2014/66795, 2014, A1. Location in patent: Paragraph 0175
[2] Patent: US2004/204427, 2004, A1. Location in patent: Page/Page column 42
4-FLUORO-3-METHOXYBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-FLUORO-3-METHOXYBENZOIC ACID manufacturers
- Product
- 4-FLUORO-3-METHOXYBENZOIC ACID 82846-18-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-18
- Product
- 4-FLUORO-3-METHOXYBENZOIC ACID 82846-18-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-11
- Product
- 4-FLUORO-3-METHOXYBENZOIC ACID 82846-18-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11