5-FLUORO-2-METHOXYBENZOIC ACID
- Product Name
- 5-FLUORO-2-METHOXYBENZOIC ACID
- CAS No.
- 394-04-7
- Chemical Name
- 5-FLUORO-2-METHOXYBENZOIC ACID
- Synonyms
- BUTTPARK 32\01-79;RARECHEM AL BO 1468;5-FLUORO-2-METHOXYBENZOIC;5-fluoro-2-methxybenzoic acid;5-FLUORO-2-METHOXYBENZOIC ACID;5-Fluoro-2-Methoxylbenzoic acid;Benzoic acid,5-fluoro-2-Methoxy-;5-Fluoro-2-methoxybenzoic acid 97%;5-Fluoro-2-methoxybenzoic acid, ≥97.0%;5-Fluoro-2-Methoxybenzoic acid, JRD, 97%
- CBNumber
- CB0734989
- Molecular Formula
- C8H7FO3
- Formula Weight
- 170.14
- MOL File
- 394-04-7.mol
5-FLUORO-2-METHOXYBENZOIC ACID Property
- Melting point:
- 87-91 °C (lit.)
- Boiling point:
- 294.0±20.0 °C(Predicted)
- Density
- 1.307±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.75±0.10(Predicted)
- form
- fluffy powder
- color
- White
- Water Solubility
- Insoluble in water.
- InChI
- InChI=1S/C8H7FO3/c1-12-7-3-2-5(9)4-6(7)8(10)11/h2-4H,1H3,(H,10,11)
- InChIKey
- WPXFJBPJUGMYOD-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(F)=CC=C1OC
- CAS DataBase Reference
- 394-04-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 523097
- Product name
- 5-Fluoro-2-methoxybenzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $107.5
- Updated
- 2025/07/31
- Product number
- F596123
- Product name
- 5-Fluoro-2-methoxybenzoic acid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- F596123
- Product name
- 5-Fluoro-2-methoxybenzoic acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- PC0292
- Product name
- 5-Fluoro-2-methoxybenzoic acid
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- 2621-3-27
- Product name
- 5-Fluoro-2-methoxybenzoic acid
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
5-FLUORO-2-METHOXYBENZOIC ACID Chemical Properties,Usage,Production
Chemical Properties
off-white powder
Uses
5-Fluoro-3-hydroxy-2-methylbenzoic acid 1 was synthesized from 5-fluoro-2-methylbenzoic acid by nitration, reduction, diazotization and hydrolysis. Another methylcarbamoyl-substituted benzylamine 12 was synthesized from 5-fluoro-2-methylbenzoic acid via the sequential bromination,azido replacement and the reduction.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
151793-20-3
394-04-7
(2) Synthesis of 2-methoxy-5-fluorobenzoic acid: Methyl 5-fluoro-2-methoxybenzoate (0.61 g) was added to 10% potassium hydroxide solution in methanol (V/V=1:2) and the reaction was stirred at room temperature. The reaction progress was monitored by thin layer chromatography (TLC). After completion of the reaction, methanol was removed by distillation under reduced pressure. Subsequently, the pH of the reaction solution was adjusted to 2-3 with 2M hydrochloric acid solution and a white solid was precipitated. The solid was collected by filtration and washed with deionized water and dried under vacuum to give 2-methoxy-5-fluorobenzoic acid in 96% yield.
References
[1] Patent: CN103965066, 2016, B. Location in patent: Paragraph 0054; 0055; 0056
[2] Patent: WO2017/214367, 2017, A1. Location in patent: Page/Page column 95
5-FLUORO-2-METHOXYBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-FLUORO-2-METHOXYBENZOIC ACID manufacturers
- Product
- 5-FLUORO-2-METHOXYBENZOIC ACID 394-04-7
- Price
- US $10.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 1 ton
- Release date
- 2025-08-29
- Product
- 5-fluoro-2-methoxybenzoic acid 394-04-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2025-08-26
- Product
- 5-Fluoro-2-methoxybenzoic acid 394-04-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-26