Raptinal

Product Name: Raptinal
CAS No.: 1176-09-6
Chemical Name: Raptinal
Synonyms: Raptinal;Raptinal, 10 mM in DMSO;[9,9'-Bi-9H-fluorene]-9,9'-dicarboxaldehyde;9H,9'H-[9,9'-Bifluorene]-9,9'-dicarbaldehyde
CBNumber: CB03969481
Molecular Formula: C28H18O2
Formula Weight: 386.44
MOL File: 1176-09-6.mol

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Raptinal Property

Melting point:: 219 °C
Boiling point:: 531.3±50.0 °C(Predicted)
Density: 1.378±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 33.33 mg/mL (86.25 mM; Need ultrasonic)
form: powder to crystal
color: White to Almost white

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Safety

HS Code: 2912.29.6090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: R0199
Product name: Raptinal
Purity: >96.0%(HPLC)
Packaging: 25mg
Price: $197
Updated: 2024/03/01

TCI Chemical

Product number: R0199
Product name: Raptinal
Purity: >96.0%(HPLC)
Packaging: 100mg
Price: $575
Updated: 2024/03/01

Chem-Impex

Product number: 42193
Product name: Raptinal,≥96%(HPLC)
Purity: ≥96%(HPLC)
Packaging: 100MG
Price: $602.2
Updated: 2021/12/16

AK Scientific

Product number: 1136CC
Product name: 9-(9-Formylfluoren-9-yl)fluorene-9-carbaldehyde
Packaging: 100mg
Price: $818
Updated: 2021/12/16

AK Scientific

Product number: 1136CC
Product name: 9-(9-Formylfluoren-9-yl)fluorene-9-carbaldehyde
Packaging: 25mg
Price: $313
Updated: 2021/12/16

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Raptinal Chemical Properties,Usage,Production

Uses

Raptinal showed complete cytochrome c release within 30 minutes and caspase-3 activation within one hour of exposure (10 μM). Despite its general cytotoxicity in both cancer and non-cancer cell cultures (Cell death induction EC50 = 0.6-3.4 μM in 24 hr), no hematologic toxicity was observed 7 days following single 60 mg/kg i.v. dosing in mice. Studies show th at daily i.p. injection (20 mg/kg) is efficacious in suppressing murine B16-F10 melanoma and 4T1 breast cancer expansion in vivo (by ~60% and 50% in 6 days, respectively).

Biological Activity

Raptinal is a cell-permeable bifluorene-dicarbaldehyde compound th at acts as a rapid activator of mitochondrial pathway-mediated intrinsic apoptosis.

Raptinal Preparation Products And Raw materials

Raw materials

Preparation Products

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Raptinal Suppliers

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1176-09-6, RaptinalRelated Search:

Raptinal

[9,9'-Bi-9H-fluorene]-9,9'-dicarboxaldehyde

9H,9'H-[9,9'-Bifluorene]-9,9'-dicarbaldehyde

Raptinal, 10 mM in DMSO

1176-09-6