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MEZEREIN

Product Name
MEZEREIN
CAS No.
34807-41-5
Chemical Name
MEZEREIN
Synonyms
meserein;MEZEREIN;Nsc239072;MEZEREIN,HIGHPURITY;MEZEREIN FROM EUPHORBIACEAE;12β-[(e,e)-5-phenyl-2,4-pentadienoyloxy]daphnetoxin;12BETA-[(E,E)-5-PHENYL-2,4-PENTADIENOYLOXY]DAPHNETOXIN;12-((1-oxo-5-phenyl-2,4-pentadienyl)oxy)-,(12-beta(e,e))-daphnetoxi;2,4-Pentadienoic acid, 5-phenyl-, (2S,3aR,3bS,3cS,4aR,5S,5aS,8aR,8bR,9R,10R,10aS)-3a,3b,3c,4a,5,5a,8a,9,10,10a-decahydro-5,5a-dihydroxy-4a-(hydroxymethyl)-7,9-dimethyl-10a-(1-methylethenyl)-6-oxo-2-phenyl-6H-2,8b-epoxyoxireno[6,7]azuleno[5,4-e]-1,3-benzodioxol-10-yl ester, (2E,4E)-;2,4-Pentadienoic acid, 5-phenyl-, 3A,3B,3C,4A,5A,6,8A,9,10,10A-decahydro-5,5A-dihydroxy-4A-(hydroxymethyl)-7,9-dimethyl-10A-((1-methylethenyl)-6-oxo-2-phenyl-5H-2,8B-epoxyoxireno[6,7]azuleno[5,4-E]-1,3-benzodioxol-10-yl ester, [2S-[2.alpha.,3A.beta.,3B.beta.,3C.beta.,4A.beta.,5.beta.,5A.beta.,8A.beta.,8B.alpha.,9.alpha.,10.beta.(E,E),10A.beta.]]-
CBNumber
CB0396990
Molecular Formula
C38H38O10
Formula Weight
654.7
MOL File
34807-41-5.mol
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MEZEREIN Property

Melting point:
267°C (rough estimate)
Boiling point:
599.84°C (rough estimate)
Density 
1.1724 (rough estimate)
refractive index 
1.5376 (estimate)
storage temp. 
−20°C
EPA Substance Registry System
Daphnetoxin, 12-[(1-oxo-5-phenyl-2,4-pentadienyl)oxy]-, [12.beta.(E,E)]- (34807-41-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
38
Safety Statements 
22-24/25
RIDADR 
2811
WGK Germany 
3
RTECS 
HB5425500
F 
10-21
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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MEZEREIN Chemical Properties,Usage,Production

Uses

Mezerein is a PKC activator and second stage tumor promoter.

General Description

Crystals or white powder.

Air & Water Reactions

MEZEREIN is sensitive to air and light.

Fire Hazard

Flash point data for MEZEREIN are not available. MEZEREIN is probably combustible.

MEZEREIN Preparation Products And Raw materials

Raw materials

Preparation Products

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MEZEREIN Suppliers

China 4 Japan 1 Switzerland 3 United States 10 Global 18
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80

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  • MEZEREIN
  • 12BETA-[(E,E)-5-PHENYL-2,4-PENTADIENOYLOXY]DAPHNETOXIN
  • 12-((1-oxo-5-phenyl-2,4-pentadienyl)oxy)-,(12-beta(e,e))-daphnetoxi
  • meserein
  • MEZEREIN FROM EUPHORBIACEAE
  • 12β-[(e,e)-5-phenyl-2,4-pentadienoyloxy]daphnetoxin
  • MEZEREIN,HIGHPURITY
  • 2,4-Pentadienoic acid, 5-phenyl-, 3A,3B,3C,4A,5A,6,8A,9,10,10A-decahydro-5,5A-dihydroxy-4A-(hydroxymethyl)-7,9-dimethyl-10A-((1-methylethenyl)-6-oxo-2-phenyl-5H-2,8B-epoxyoxireno[6,7]azuleno[5,4-E]-1,3-benzodioxol-10-yl ester, [2S-[2.alpha.,3A.beta.,3B.beta.,3C.beta.,4A.beta.,5.beta.,5A.beta.,8A.beta.,8B.alpha.,9.alpha.,10.beta.(E,E),10A.beta.]]-
  • Nsc239072
  • 2,4-Pentadienoic acid, 5-phenyl-, (2S,3aR,3bS,3cS,4aR,5S,5aS,8aR,8bR,9R,10R,10aS)-3a,3b,3c,4a,5,5a,8a,9,10,10a-decahydro-5,5a-dihydroxy-4a-(hydroxymethyl)-7,9-dimethyl-10a-(1-methylethenyl)-6-oxo-2-phenyl-6H-2,8b-epoxyoxireno[6,7]azuleno[5,4-e]-1,3-benzodioxol-10-yl ester, (2E,4E)-
  • 34807-41-5
  • C38H38O10
  • Protein Kinase Activators
  • Protein Phosphorylation
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience