Trimethyl orthobenzoate

Product Name: Trimethyl orthobenzoate
CAS No.: 707-07-3
Chemical Name: Trimethyl orthobenzoate
Synonyms: (Trimethoxymethyl)benzene;Methyl orthobenzoate;Benzene, (trimethoxymethyl)-;SKL283;NSC-67391;Orthobenzoate;trimethyl benzoate;Intedanib Impurity 6;TRIMETHYL-O-BENZOATE;Sunitinib Impurity 71
CBNumber: CB9160297
Molecular Formula: C10H14O3
Formula Weight: 182.22
MOL File: 707-07-3.mol

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Trimethyl orthobenzoate Property

Boiling point:: 87-88 °C/7 mmHg (lit.)
Density: 1.061 g/mL at 25 °C (lit.)
refractive index: n20/D 1.489(lit.)
Flash point:: 180 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in organic solvents.
form: Liquid
color: Clear colorless
Sensitive: Moisture Sensitive
BRN: 777623
Stability:: Hygroscopic
InChIKey: IECKAVQTURBPON-UHFFFAOYSA-N
CAS DataBase Reference: 707-07-3(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, (trimethoxymethyl)-(707-07-3)
EPA Substance Registry System: Benzene, (trimethoxymethyl)- (707-07-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39-37/39
WGK Germany: 3
TSCA: Yes
HS Code: 29163100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 164534
Product name: Trimethyl orthobenzoate
Purity: 98%
Packaging: 50g
Price: $501
Updated: 2025/07/31

Sigma-Aldrich

Product number: 164534
Product name: Trimethyl orthobenzoate
Purity: 98%
Packaging: 10g
Price: $99.4
Updated: 2023/06/20

TCI Chemical

Product number: T2287
Product name: Trimethyl Orthobenzoate
Purity: >95.0%(GC)
Packaging: 5g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: T2287
Product name: Trimethyl Orthobenzoate
Purity: >95.0%(GC)
Packaging: 25g
Price: $54
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: CHM0032532
Product name: TRIMETHYL ORTHOBENZOATE
Purity: 95.00%
Packaging: 1G
Price: $597.87
Updated: 2021/12/16

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Trimethyl orthobenzoate Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 1661, 1950 DOI: 10.1021/ja01160a067

General Description

Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.

Trimethyl orthobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Trimethyl orthobenzoate Suppliers

Belgium 1 Canada 1 China 230 Europe 2 Germany 5 India 26 Japan 4 Switzerland 2 United Kingdom 7 United States 18 Global 296

Beijing Taiya Jie Technology Development Co., Ltd.

Tel: 021-33690831-8001 13552411790
Fax: 021-33690831
Email: postmaster@tyjchem.cn
Country: China
ProdList: 1542
Advantage: 55

Jinan XuanDe Chemical Co., Ltd.

Tel: 0531-88803958 18866891188
Fax: 0531-82777287
Email: 18853169188@163.com
Country: China
ProdList: 192
Advantage: 58

Shandong Xuanshuo Pharmaceutical Technology Co. LTD

Tel: 15269103900
Email: suchangzhou@shiningpharm.com
Country: China
ProdList: 319
Advantage: 58

Shandong Yinsheng Pharmaceutical Technology Co., Ltd

Tel: 18865947357 18865947357;
Email: liguiling16888@163.com
Country: China
ProdList: 46
Advantage: 58

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 5179
Advantage: 58

Hangzhou Beishengyuan Biotechnology Co., Ltd

Tel: 0571-15068777134 15068777134
Email: 1289372011@qq.com
Country: China
ProdList: 4492
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259138 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

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View Lastest Price from Trimethyl orthobenzoate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Trimethyl Orthobenzoate 707-07-3
Price: US $99.00-45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-12-18

Henan Aochuang Chemical Co.,Ltd.

Product: Trimethyl orthobenzoate 707-07-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Shaanxi Dideu New Materials Co. Ltd

Product: Trimethyl orthobenzoate 707-07-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-22

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Trimethyl Orthobenzoate Liquid

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707-07-3

C6H5COCH33

Building Blocks

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bc0001

707-07-3