ChemicalBook > CAS DataBase List > Trimethyl orthobenzoate

Trimethyl orthobenzoate

Product Name
Trimethyl orthobenzoate
CAS No.
707-07-3
Chemical Name
Trimethyl orthobenzoate
Synonyms
(Trimethoxymethyl)benzene;Methyl orthobenzoate;Benzene, (trimethoxymethyl)-;SKL283;NSC-67391;Orthobenzoate;trimethyl benzoate;Intedanib Impurity 6;TRIMETHYL-O-BENZOATE;Sunitinib Impurity 71
CBNumber
CB9160297
Molecular Formula
C10H14O3
Formula Weight
182.22
MOL File
707-07-3.mol
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Trimethyl orthobenzoate Property

Boiling point:
87-88 °C/7 mmHg (lit.)
Density 
1.061 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.489(lit.)
Flash point:
180 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in organic solvents.
form 
Liquid
color 
Clear colorless
Sensitive 
Moisture Sensitive
BRN 
777623
Stability:
Hygroscopic
InChIKey
IECKAVQTURBPON-UHFFFAOYSA-N
CAS DataBase Reference
707-07-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, (trimethoxymethyl)-(707-07-3)
EPA Substance Registry System
Benzene, (trimethoxymethyl)- (707-07-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-37/39
WGK Germany 
3
TSCA 
Yes
HS Code 
29163100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
164534
Product name
Trimethyl orthobenzoate
Purity
98%
Packaging
50g
Price
$486
Updated
2024/03/01
Sigma-Aldrich
Product number
164534
Product name
Trimethyl orthobenzoate
Purity
98%
Packaging
10g
Price
$99.4
Updated
2023/06/20
TCI Chemical
Product number
T2287
Product name
Trimethyl Orthobenzoate
Purity
>95.0%(GC)
Packaging
5g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
T2287
Product name
Trimethyl Orthobenzoate
Purity
>95.0%(GC)
Packaging
25g
Price
$52
Updated
2024/03/01
Alfa Aesar
Product number
A10270
Product name
Trimethyl orthobenzoate, 98%
Packaging
10g
Price
$40.65
Updated
2024/03/01
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Trimethyl orthobenzoate Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 1661, 1950 DOI: 10.1021/ja01160a067

General Description

Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.

Trimethyl orthobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Trimethyl orthobenzoate Suppliers

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View Lastest Price from Trimethyl orthobenzoate manufacturers

Hong Kong Excellence Biotechnology Co., Ltd.
Product
Trimethyl orthobenzoate 707-07-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20tons
Release date
2023-10-12
Sigma Audley
Product
Trimethyl orthobenzoate 707-07-3
Price
US $45.00-35.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
200tons/year
Release date
2024-01-15
Weijer International Trade (Hebei) Co., Ltd
Product
Trimethyl orthobenzoate 707-07-3
Price
US $1.00/KG
Min. Order
1KG
Purity
>99%
Supply Ability
200T
Release date
2023-03-22

707-07-3, Trimethyl orthobenzoateRelated Search:

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