Trimethyl orthobenzoate
- Product Name
- Trimethyl orthobenzoate
- CAS No.
- 707-07-3
- Chemical Name
- Trimethyl orthobenzoate
- Synonyms
- (Trimethoxymethyl)benzene;Methyl orthobenzoate;Benzene, (trimethoxymethyl)-;SKL283;NSC-67391;Orthobenzoate;trimethyl benzoate;Intedanib Impurity 6;TRIMETHYL-O-BENZOATE;Sunitinib Impurity 71
- CBNumber
- CB9160297
- Molecular Formula
- C10H14O3
- Formula Weight
- 182.22
- MOL File
- 707-07-3.mol
Trimethyl orthobenzoate Property
- Boiling point:
- 87-88 °C/7 mmHg (lit.)
- Density
- 1.061 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.489(lit.)
- Flash point:
- 180 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in organic solvents.
- form
- Liquid
- color
- Clear colorless
- Sensitive
- Moisture Sensitive
- BRN
- 777623
- Stability:
- Hygroscopic
- InChIKey
- IECKAVQTURBPON-UHFFFAOYSA-N
- CAS DataBase Reference
- 707-07-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, (trimethoxymethyl)-(707-07-3)
- EPA Substance Registry System
- Benzene, (trimethoxymethyl)- (707-07-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-37/39
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29163100
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 164534
- Product name
- Trimethyl orthobenzoate
- Purity
- 98%
- Packaging
- 50g
- Price
- $486
- Updated
- 2024/03/01
- Product number
- 164534
- Product name
- Trimethyl orthobenzoate
- Purity
- 98%
- Packaging
- 10g
- Price
- $99.4
- Updated
- 2023/06/20
- Product number
- T2287
- Product name
- Trimethyl Orthobenzoate
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $18
- Updated
- 2024/03/01
- Product number
- T2287
- Product name
- Trimethyl Orthobenzoate
- Purity
- >95.0%(GC)
- Packaging
- 25g
- Price
- $52
- Updated
- 2024/03/01
- Product number
- A10270
- Product name
- Trimethyl orthobenzoate, 98%
- Packaging
- 10g
- Price
- $40.65
- Updated
- 2024/03/01
Trimethyl orthobenzoate Chemical Properties,Usage,Production
Chemical Properties
clear colorless liquid
Uses
Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 1661, 1950 DOI: 10.1021/ja01160a067
General Description
Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.
Trimethyl orthobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Trimethyl orthobenzoate manufacturers
- Product
- Trimethyl orthobenzoate 707-07-3
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 20tons
- Release date
- 2023-10-12
- Product
- Trimethyl orthobenzoate 707-07-3
- Price
- US $3.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10 tons
- Release date
- 2024-03-13
- Product
- Trimethyl orthobenzoate 707-07-3
- Price
- US $45.00-35.00/kg
- Min. Order
- 1kg
- Purity
- 99.8%
- Supply Ability
- 200tons/year
- Release date
- 2024-01-15