Trimethyl orthobenzoate

Product Name: Trimethyl orthobenzoate
CAS No.: 707-07-3
Chemical Name: Trimethyl orthobenzoate
Synonyms: (Trimethoxymethyl)benzene;Methyl orthobenzoate;Benzene, (trimethoxymethyl)-;SKL283;NSC-67391;Orthobenzoate;trimethyl benzoate;Intedanib Impurity 6;TRIMETHYL-O-BENZOATE;Sunitinib Impurity 71
CBNumber: CB9160297
Molecular Formula: C10H14O3
Formula Weight: 182.22
MOL File: 707-07-3.mol

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Trimethyl orthobenzoate Property

Boiling point:: 87-88 °C/7 mmHg (lit.)
Density: 1.061 g/mL at 25 °C (lit.)
refractive index: n20/D 1.489(lit.)
Flash point:: 180 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in organic solvents.
form: Liquid
color: Clear colorless
Sensitive: Moisture Sensitive
BRN: 777623
Stability:: Hygroscopic
InChIKey: IECKAVQTURBPON-UHFFFAOYSA-N
CAS DataBase Reference: 707-07-3(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, (trimethoxymethyl)-(707-07-3)
EPA Substance Registry System: Benzene, (trimethoxymethyl)- (707-07-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39-37/39
WGK Germany: 3
TSCA: Yes
HS Code: 29163100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 164534
Product name: Trimethyl orthobenzoate
Purity: 98%
Packaging: 50g
Price: $501
Updated: 2025/07/31

Sigma-Aldrich

Product number: 164534
Product name: Trimethyl orthobenzoate
Purity: 98%
Packaging: 10g
Price: $99.4
Updated: 2023/06/20

TCI Chemical

Product number: T2287
Product name: Trimethyl Orthobenzoate
Purity: >95.0%(GC)
Packaging: 5g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: T2287
Product name: Trimethyl Orthobenzoate
Purity: >95.0%(GC)
Packaging: 25g
Price: $54
Updated: 2025/07/31

AK Scientific

Product number: 9303AL
Product name: Trimethyl Orthobenzoate
Packaging: 100g
Price: $161
Updated: 2021/12/16

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Trimethyl orthobenzoate Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 1661, 1950 DOI: 10.1021/ja01160a067

General Description

Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.

Trimethyl orthobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Trimethyl orthobenzoate Suppliers

Belgium 1 Canada 1 China 228 Europe 2 Germany 5 India 26 Japan 4 Switzerland 2 United Kingdom 7 United States 18 Global 294

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View Lastest Price from Trimethyl orthobenzoate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Trimethyl Orthobenzoate 707-07-3
Price: US $99.00-45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-12-18

Henan Aochuang Chemical Co.,Ltd.

Product: Trimethyl orthobenzoate 707-07-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Shaanxi Dideu New Materials Co. Ltd

Product: Trimethyl orthobenzoate 707-07-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-22

707-07-3, Trimethyl orthobenzoateRelated Search:

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Trimethyl orthobenzoate 98%

NSC-67391

Intedanib Impurity 6

TRIMETHYL ORTHOBENZOATE

TRIMETHYL-O-BENZOATE

TriMethyl Orthobenzoate, 95%(GC)

Trimethyl Orthobenzoate Liquid

trimethyl benzoate

SKL283

Trimethyl orthobenzoate (Nintedanib Impurity)

Sunitinib Impurity 71

707-07-3

C6H5COCH33

Building Blocks

Oxygen Compounds

Organic Building Blocks

Acetals/Ketals/Ortho Esters

Organic Building Blocks

Oxygen Compounds

bc0001

707-07-3