GIGAVLKVLTTGLPALISWIKRKRQ-OH

Product Name: GIGAVLKVLTTGLPALISWIKRKRQ-OH
CAS No.: 123168-46-7
Chemical Name: GIGAVLKVLTTGLPALISWIKRKRQ-OH
Synonyms: MELITTIN;MELITTIN (FREE ACID);Melittin trifluoroacetate;GIGAVLKVLTTGLPALISWIKRKRQ-OH;GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN: GIGAVLKVLTTGLPALISWIKRKRQQ
CBNumber: CB0401937
Molecular Formula: C131H228N38O32
Formula Weight: 2847.45
MOL File: Mol file

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PRK0000269
Product name: MELITTIN FREE ACID
Purity: 95.00%
Packaging: 0.5MG
Price: $654.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PRK0000269
Product name: MELITTIN FREE ACID
Purity: 95.00%
Packaging: 1MG
Price: $796
Updated: 2021/12/16

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GIGAVLKVLTTGLPALISWIKRKRQ-OH Chemical Properties,Usage,Production

Uses

Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways[1][2].

in vivo

Melittin (intraperitoneal inoculation) increases 13,14-dihydro-15-keto-PGE2 levels in peripheral blood of mice^[1].

References

[1] Hassid A, Levine L. Stimulation of phospholipase activity and prostaglandin biosynthesis by melittin in cell culture and in vivo. Res Commun Chem Pathol Pharmacol. 1977. PMID:928951
[2] Memariani H, Memariani M. Anti-fungal properties and mechanisms of melittin. Appl Microbiol Biotechnol. 2020 Aug;104(15):6513-6526. DOI:10.1007/s00253-020-10701-0

GIGAVLKVLTTGLPALISWIKRKRQ-OH Preparation Products And Raw materials

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123168-46-7, GIGAVLKVLTTGLPALISWIKRKRQ-OHRelated Search:

MELITTIN MELITTIN

MELITTIN

MELITTIN (FREE ACID)

GIGAVLKVLTTGLPALISWIKRKRQ-OH

GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN: GIGAVLKVLTTGLPALISWIKRKRQQ

Melittin trifluoroacetate

123168-46-7

23168-46-7