Description Preparation
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4-Pyridyl acetone

Description Preparation
Product Name
4-Pyridyl acetone
CAS No.
6304-16-1
Chemical Name
4-Pyridyl acetone
Synonyms
1-(PYRIDIN-4-YL)PROPAN-2-ONE;1-(4-Pyridyl)acetone;1-(4-Pyridyl)-2-acetone;1-(4-PYRIDINYL)-2-PROPANONE;Einecs 228-605-7;-Pyridyl acetone;4-Pyridinolacetone;4-ACETONYLPYRIDINE;(4-PYRIDYL)ACETONE;4-pyridinyl acetone
CBNumber
CB0402505
Molecular Formula
C8H9NO
Formula Weight
135.16
MOL File
6304-16-1.mol
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4-Pyridyl acetone Property

Melting point:
13°C
Boiling point:
143°C 20mm
Density 
1.046±0.06 g/cm3(Predicted)
refractive index 
1.5225
Flash point:
143°C/20mm
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Oil
pka
4.90±0.10(Predicted)
color 
Light Brown to Brown
Water Solubility 
Slightly soluble in water.
BRN 
110960
InChI
InChI=1S/C8H9NO/c1-7(10)6-8-2-4-9-5-3-8/h2-5H,6H2,1H3
InChIKey
ILRVKOYYFFNXDB-UHFFFAOYSA-N
SMILES
C(C1C=CN=CC=1)C(=O)C
CAS DataBase Reference
6304-16-1(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-37
HS Code 
29337900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
P2039
Product name
(4-Pyridyl)acetone
Purity
>98.0%(GC)
Packaging
1g
Price
$35
Updated
2021/12/16
TCI Chemical
Product number
P2039
Product name
(4-Pyridyl)acetone
Purity
>98.0%(GC)
Packaging
5g
Price
$136
Updated
2021/12/16
Alfa Aesar
Product number
L18667
Product name
(4-Pyridyl)acetone, 98%
Packaging
5g
Price
$139
Updated
2021/12/16
Alfa Aesar
Product number
L18667
Product name
(4-Pyridyl)acetone, 98%
Packaging
1g
Price
$39.7
Updated
2021/12/16
TRC
Product number
P991845
Product name
(4-Pyridyl)acetone
Packaging
5g
Price
$85
Updated
2021/12/16
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4-Pyridyl acetone Chemical Properties,Usage,Production

Description

1-(4-pyridyl)acetone is a yellow liquid, which is a key intermediate for synthesizing cardiac drug Milrinone.

Preparation

4-Pyridyl acetone can be prepared by reacting with 4-picoline and phenyllithium and ethyl acetate.

Physical properties

4-pyridyl acetone is a Light yellow to yellow liquid.

Uses

(4-Pyridyl)acetone is a reactant in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 3297, 1984 DOI: 10.1016/S0040-4039(01)81368-X

4-Pyridyl acetone Preparation Products And Raw materials

Raw materials

Hexamethylphosphoramide Ethanol 4-Methylpyridine Phenyllithium Chloroform Diisopropylamine Tetrahydrofuran Ethyl acetate Acetic acid PETROLEUM ETHER n-Butyllithium

Preparation Products

Milrinone
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4-Pyridyl acetone Suppliers

China 197 Europe 3 Germany 6 India 7 Ireland 1 Japan 2 Slovakia 1 The Netherlands 1 United Kingdom 12 United States 30 USA 1 Global 261
ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
Camida
Tel
--
Fax
--
Email
info@camida.com
Country
Europe
ProdList
3704
Advantage
71
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View Lastest Price from 4-Pyridyl acetone manufacturers

Nanjing Kaitian Chemical Co., LTD
Product
1-(4-Pyridyl)acetone 6304-16-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2tons
Release date
2022-12-06
Henan Aochuang Chemical Co.,Ltd.
Product
4-Pyridyl acetone 6304-16-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-13
Dideu Industries Group Limited
Product
4-Pyridyl acetone 6304-16-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-25

6304-16-1, 4-Pyridyl acetoneRelated Search:

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