ChemicalBook > CAS DataBase List > 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE
2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE
- Product Name
- 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE
- CAS No.
- 73568-26-0
- Chemical Name
- 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE
- Synonyms
- AKOS AU36-M571;ASISCHEM D48938;TIMTEC-BB SBB000448;IFLAB-BB F0805-0001;2-CHLORO-8-METHYLQUINOLINE-3-CAR;2-Chloro-3-formyl-8-methylquinoline;2-CHLORO-8-METHYLQUINOLINE-3-CARBOXALDE;2-CHLORO-8-METHYL-QUINOLINE-3-CARBALDEHYDE;2-Chloro-8-methylquinoline-3-carboxaldehye;2-CHLORO-8-METHYLQUINOLINE-3-CARBOXALDEHYDE
- CBNumber
- CB0405359
- Molecular Formula
- C11H8ClNO
- Formula Weight
- 205.64
- MOL File
- 73568-26-0.mol
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2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE Property
- Melting point:
- 138-141 °C (lit.)
- Boiling point:
- 350.8±37.0 °C(Predicted)
- Density
- 1.312±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- -1.29±0.50(Predicted)
- form
- Crystalline Powder
- color
- Yellow to yellow-brown
- InChI
- 1S/C11H8ClNO/c1-7-3-2-4-8-5-9(6-14)11(12)13-10(7)8/h2-6H,1H3
- InChIKey
- YPBRSXNRWFUUOE-UHFFFAOYSA-N
- SMILES
- [H]C(=O)c1cc2cccc(C)c2nc1Cl
- CAS DataBase Reference
- 73568-26-0(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- C3109
- Product name
- 2-Chloro-8-methylquinoline-3-carboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
TCI Chemical
- Product number
- C3109
- Product name
- 2-Chloro-8-methylquinoline-3-carboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $105
- Updated
- 2021/12/16
TRC
- Product number
- C587795
- Product name
- 2-Chloro-8-methylquinoline-3-carboxaldehyde
- Packaging
- 5g
- Price
- $305
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC54326
- Product name
- 2-Chloro-8-methylquinoline-3-carboxaldehyde
- Packaging
- 5G
- Price
- $200
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 4H15-5-64
- Product name
- 2-Chloro-8-methylquinoline-3-carboxaldehyde
- Packaging
- 5G
- Price
- $200
- Updated
- 2021/12/16
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2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
Yellow to yellow-brown crystalline powder
Uses
2-Chloro-8-methylquinoline-3-carboxaldehyde acts as a reagent in the synthesis of 2-Azetidinones from 2-chloro-8-Me-3-quinolinecarbaldehyde as potential antimicrobial agents, preparation and antibacterial activity of thiazoloquinoline Schiff bases as potential antibacterial agents.
Synthesis
0.3 mol of aniline, 40 mL of glacial acetic acid and 0.4 g of zinc powder were added to a round-bottomed flask fitted with a fractionating column and a thermometer mounted at the top of the column, and the evaporated water and acetic acid were collected in a beaker. The water and acetic acid were collected in a beaker and slowly heated for 15 min and then distilled at about 105 ??C. When the temperature kept decreasing, the heating was stopped and the end point was reached. The reaction was poured into ice water under stirring conditions while still hot to precipitate a solid, cooled, and filtered by pumping to give crude acetanilide, which was recrystallized with water to give white, pure 2-methylacetanilide.
The product obtained in the previous step 2-methylacetanilide 0.05 mol, DMF 0.15 mol was added to a four-necked flask, fitted with a thermometer, mechanical stirrer, condenser tube, mechanical stirring in an ice bath at a temperature of less than 10 ??, slowly added 0.35 mol of POCl 3 dropwise, the temperature was raised to 75 ?? after the completion of dropwise addition and stirred the reaction for 12 h, the color was changed from a light yellow oily liquid to an orange-red liquid, and the reaction was completed. After the reaction was complete, the heating was stopped, and the reactants were slowly poured into 400 mL of ice water with stirring, left to stand, and the precipitated solid was filtered, washed with water for three times, dried in air, and then recrystallized from ethyl acetate to obtain the light-yellow needle-like crystals of 2-chloro-8-methylquinoline-3-carbaldehyde. 2-Chloro-8-methylquinoline-3-carboxaldehyde prepared by acetanilide cyclosynthesis was characterized by mass spectrometry, elemental analysis, infrared, and nuclear magnetic resonance spectroscopy as follows: light yellow acicular crystals, 90% yield, mp. 150-152 ??C.2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE Suppliers
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View Lastest Price from 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE 73568-26-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
Career Henan Chemical Co
- Product
- 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE 73568-26-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Kg/T
- Release date
- 2019-12-19
73568-26-0, 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDERelated Search:
2-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBALDEHYDE
2-CHLORO-6,8-DIMETHYLQUINOLINE-3-METHANOL
2-CHLORO-7-METHOXY-QUINOLINE-3-CARBALDEHYDE
2-CHLORO-6-METHYL-3-QUINOLINE CARBOXALDEHYDE
AKOS AU36-M572
2-CHLORO-6-ETHYLQUINOLINE-3-CARBALDEHYDE
2-CHLORO-7-METHOXYQUINOLINE-3-METHANOL
2-CHLORO-7-ETHOXY-3-QUINOLINECARBALDEHYDE
2-CHLORO-6-METHOXYQUINOLINE-3-METHANOL
2-CHLORO-7-FLUOROQUINOLINE-3-CARBOXALDEHYDE
2-chloro-8-fluoroquinoline-3-carbaldehyde
2-Chloro-7-(trifluoromethoxy)quinoline-3-carbaldehyde
(2-CHLORO-8-METHYLQUINOLIN-3-YL)METHANOL
ASISCHEM D48940
2-CHLORO-6-FLUOROQUINOLINE-3-METHANOL
2-CHLORO-6-METHOXYQUINOLINE-3-CARBALDEHYDE
2-CHLORO-8-ETHYL-QUINOLINE-3-CARBALDEHYDE
2-chloro-7-isopropoxyquinoline-3-carbaldehyde