2-Chloro-6-methyl-3-quinolinecarbaldehyde
- Product Name
- 2-Chloro-6-methyl-3-quinolinecarbaldehyde
- CAS No.
- 73568-27-1
- Chemical Name
- 2-Chloro-6-methyl-3-quinolinecarbaldehyde
- Synonyms
- AKOS AU36;AKOS AU36-M570;ASISCHEM U98021;AKOS BBS-00007323;TIMTEC-BB SBB000449;IFLAB-BB F0805-0003;2-Chloro-3-formyl-6-methylquinoline;2-CHLORO-6-METHYLQUINOLINE-3-CARBOXALDE;2-CHLORO-6-METHYLQUINOLINE-3-CARBALDEHYDE;2-CHLORO-6-METHYL-3-QUINOLINECARBALDEHYDE
- CBNumber
- CB9135677
- Molecular Formula
- C11H8ClNO
- Formula Weight
- 205.64
- MOL File
- 73568-27-1.mol
2-Chloro-6-methyl-3-quinolinecarbaldehyde Property
- Melting point:
- 120-125 °C (lit.)
- Boiling point:
- 350.8±37.0 °C(Predicted)
- Density
- 1.312±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- -1.11±0.50(Predicted)
- color
- Light orange to Yellow to Green
- CAS DataBase Reference
- 73568-27-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 535648
- Product name
- 2-Chloro-6-methylquinoline-3-carboxaldehyde
- Purity
- 96%
- Packaging
- 5g
- Price
- $105
- Updated
- 2023/06/20
- Product number
- C2953
- Product name
- 2-Chloro-6-methylquinoline-3-carboxaldehyde
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $74
- Updated
- 2024/03/01
- Product number
- C2953
- Product name
- 2-Chloro-6-methylquinoline-3-carboxaldehyde
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $295
- Updated
- 2024/03/01
- Product number
- C587768
- Product name
- 2-Chloro-6-methylquinoline-3-carboxaldehyde
- Packaging
- 10g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- FC54324
- Product name
- 2-Chloro-6-methylquinoline carboxaldehyde
- Packaging
- 5G
- Price
- $134.8
- Updated
- 2021/12/16
2-Chloro-6-methyl-3-quinolinecarbaldehyde Chemical Properties,Usage,Production
Uses
2-Chloro-6-methylquinoline-3-carboxaldehyde (cas# 73568-27-1) is a compound useful in organic synthesis.
Synthesis
68-12-2
103-89-9
73568-27-1
Step 2: Phosphorus trichloride (237.2 g, 1.55 mol) was added dropwise to stirred N,N-dimethylformamide (40.4 g, 552.74 mmol) at 0 °C. N-p-tolylacetamide (33 g, 221.19 mmol) was subsequently added and the reaction mixture was kept stirring at reflux temperature overnight. Upon completion of the reaction, the reaction was quenched with 3000 mL of H2O/ice mixture. The pH of the mixture was adjusted to 9 by addition of Na2CO3. The reaction mixture was extracted with dichloromethane (3 x 3000 mL). The organic phases were combined and dried over anhydrous MgSO4 and subsequently concentrated under reduced pressure on a rotary evaporator. The crude product was purified by silica gel column chromatography with an eluent ratio of 1:10 ethyl acetate:hexane to give 15.3 g (34% yield) of 2-chloro-6-methylquinoline-3-carboxaldehyde as a yellow solid.LCMS detection showed a molecular ion peak of 206 (M + H)+.
References
[1] Synlett, 2001, # 2, p. 251 - 253
[2] Patent: CN104774221, 2017, B. Location in patent: Paragraph 0062
[3] Patent: CN104725431, 2017, B. Location in patent: Paragraph 0050
[4] Synthetic Communications, 2002, vol. 32, # 9, p. 1351 - 1356
[5] Journal of the Brazilian Chemical Society, 2014, vol. 25, # 2, p. 365 - 371
2-Chloro-6-methyl-3-quinolinecarbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Chloro-6-methyl-3-quinolinecarbaldehyde manufacturers
- Product
- 2-Chloro-6-methyl-3-quinolinecarbaldehyde 73568-27-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-09