ChemicalBook > CAS DataBase List > 2-Chloro-6-methyl-3-quinolinecarbaldehyde

2-Chloro-6-methyl-3-quinolinecarbaldehyde

Product Name
2-Chloro-6-methyl-3-quinolinecarbaldehyde
CAS No.
73568-27-1
Chemical Name
2-Chloro-6-methyl-3-quinolinecarbaldehyde
Synonyms
AKOS AU36;AKOS AU36-M570;ASISCHEM U98021;AKOS BBS-00007323;TIMTEC-BB SBB000449;IFLAB-BB F0805-0003;2-Chloro-3-formyl-6-methylquinoline;2-CHLORO-6-METHYLQUINOLINE-3-CARBOXALDE;2-CHLORO-6-METHYLQUINOLINE-3-CARBALDEHYDE;2-CHLORO-6-METHYL-3-QUINOLINECARBALDEHYDE
CBNumber
CB9135677
Molecular Formula
C11H8ClNO
Formula Weight
205.64
MOL File
73568-27-1.mol
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2-Chloro-6-methyl-3-quinolinecarbaldehyde Property

Melting point:
120-125 °C (lit.)
Boiling point:
350.8±37.0 °C(Predicted)
Density 
1.312±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
pka
-1.11±0.50(Predicted)
color 
Light orange to Yellow to Green
CAS DataBase Reference
73568-27-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2933.49.7000
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
535648
Product name
2-Chloro-6-methylquinoline-3-carboxaldehyde
Purity
96%
Packaging
5g
Price
$105
Updated
2023/06/20
TCI Chemical
Product number
C2953
Product name
2-Chloro-6-methylquinoline-3-carboxaldehyde
Purity
>96.0%(GC)
Packaging
5g
Price
$74
Updated
2024/03/01
TCI Chemical
Product number
C2953
Product name
2-Chloro-6-methylquinoline-3-carboxaldehyde
Purity
>96.0%(GC)
Packaging
25g
Price
$295
Updated
2024/03/01
TRC
Product number
C587768
Product name
2-Chloro-6-methylquinoline-3-carboxaldehyde
Packaging
10g
Price
$115
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC54324
Product name
2-Chloro-6-methylquinoline carboxaldehyde
Packaging
5G
Price
$134.8
Updated
2021/12/16
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2-Chloro-6-methyl-3-quinolinecarbaldehyde Chemical Properties,Usage,Production

Uses

2-Chloro-6-methylquinoline-3-carboxaldehyde (cas# 73568-27-1) is a compound useful in organic synthesis.

Synthesis

68-12-2

103-89-9

73568-27-1

Step 2: Phosphorus trichloride (237.2 g, 1.55 mol) was added dropwise to stirred N,N-dimethylformamide (40.4 g, 552.74 mmol) at 0 °C. N-p-tolylacetamide (33 g, 221.19 mmol) was subsequently added and the reaction mixture was kept stirring at reflux temperature overnight. Upon completion of the reaction, the reaction was quenched with 3000 mL of H2O/ice mixture. The pH of the mixture was adjusted to 9 by addition of Na2CO3. The reaction mixture was extracted with dichloromethane (3 x 3000 mL). The organic phases were combined and dried over anhydrous MgSO4 and subsequently concentrated under reduced pressure on a rotary evaporator. The crude product was purified by silica gel column chromatography with an eluent ratio of 1:10 ethyl acetate:hexane to give 15.3 g (34% yield) of 2-chloro-6-methylquinoline-3-carboxaldehyde as a yellow solid.LCMS detection showed a molecular ion peak of 206 (M + H)+.

References

[1] Synlett, 2001, # 2, p. 251 - 253
[2] Patent: CN104774221, 2017, B. Location in patent: Paragraph 0062
[3] Patent: CN104725431, 2017, B. Location in patent: Paragraph 0050
[4] Synthetic Communications, 2002, vol. 32, # 9, p. 1351 - 1356
[5] Journal of the Brazilian Chemical Society, 2014, vol. 25, # 2, p. 365 - 371

2-Chloro-6-methyl-3-quinolinecarbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-6-methyl-3-quinolinecarbaldehyde Suppliers

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View Lastest Price from 2-Chloro-6-methyl-3-quinolinecarbaldehyde manufacturers

Career Henan Chemical Co
Product
2-Chloro-6-methyl-3-quinolinecarbaldehyde 73568-27-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-09

73568-27-1, 2-Chloro-6-methyl-3-quinolinecarbaldehydeRelated Search:

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  • ASISCHEM U98021
  • IFLAB-BB F0805-0003
  • 2-CHLORO-6-METHYLQUINOLINE-3-CARBALDEHYDE
  • 2-CHLORO-6-METHYLQUINOLINE-3-CARBOXALDEHYDE
  • 2-CHLORO-6-METHYL-3-QUINOLINECARBALDEHYDE
  • 2-CHLORO-6-METHYL-3-QUINOLINE CARBOXALDEHYDE
  • TIMTEC-BB SBB000449
  • AKOS BBS-00007323
  • AKOS AU36-M570
  • 2-Chloro-6-methylquinoline-3-carboxaldehyde 96%
  • 2-CHLORO-6-METHYLQUINOLINE-3-CARBOXALDE
  • 2-CHLORO-6-METHYLQUINOLINE CARBOXALDEHYDE
  • AKOS AU36
  • JRH-03802, 2-Chloro-6-methylquinoline-3-carbaldehyde, 97%
  • 2-Chloro-6-methylquinoline-3-carboxaldehyde &gt
  • 3-Quinolinecarboxaldehyde, 2-chloro-6-methyl-
  • 2-Chloro-3-formyl-6-methylquinoline
  • 2-Chloro-6-methyl-3-quinolinecarbaldehyde ISO 9001：2015 REACH
  • 2-chloro 6-methyl quinoline 3-carbaldehyde 97%
  • 73568-27-1
  • Heterocyclic Building Blocks
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  • Quinolines
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  • Quinoline&Isoquinoline
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
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  • QuinolinesHeterocyclic Building Blocks