3-(Trifluoromethyl)benzaldehyde

Uses

Product Name: 3-(Trifluoromethyl)benzaldehyde
CAS No.: 454-89-7
Chemical Name: 3-(Trifluoromethyl)benzaldehyde
Synonyms: MTF-BAD;3-(three fluoroMethyl;Cinacalcet Impurity 56;3-TRIFLUORMETHYLBENZALDEHYDE;m-Trifuoromethylbenzaldehyde;M-TRIFLUOROMETHYLBENZALDEHYDE;3-TRIFLUOROMETHYLBENZYLDEHYDE;Alpha-Trifluoro-M-tolualdehyde;A,A,A-TRIFLUORO-3-TOLUALDEHYDE;A,A,A-TRIFLUORO-M-TOLUALDEHYDE
CBNumber: CB2759919
Molecular Formula: C8H5F3O
Formula Weight: 174.12
MOL File: 454-89-7.mol

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3-(Trifluoromethyl)benzaldehyde Property

Boiling point:: 83-86 °C30 mm Hg(lit.)
Density: 1.301 g/mL at 25 °C(lit.)
refractive index: n20/D 1.465(lit.)
Flash point:: 155 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Liquid
color: Clear colorless to very slightly orange
Specific Gravity: 1.301
Sensitive: Air Sensitive
BRN: 2327537
InChIKey: NMTUHPSKJJYGML-UHFFFAOYSA-N
CAS DataBase Reference: 454-89-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzaldehyde, 3-(trifluoromethyl)-(454-89-7)
EPA Substance Registry System: Benzaldehyde, 3-(trifluoromethyl)- (454-89-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN3082 - class 9 - PG 3 - DOT NA1993 - Environmentally hazardous substances, liquid, n.o.s. HI: all (not BR)
WGK Germany: 3
F: 10-23
TSCA: T
HazardClass: IRRITANT
HS Code: 29130000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196878
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: 97%
Packaging: 25g
Price: $42.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 196878
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: 97%
Packaging: 5g
Price: $61.8
Updated: 2024/03/01

TCI Chemical

Product number: T1399
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: >95.0%(GC)
Packaging: 5g
Price: $34
Updated: 2024/03/01

TCI Chemical

Product number: T1399
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: >95.0%(GC)
Packaging: 25g
Price: $98
Updated: 2024/03/01

Alfa Aesar

Product number: A10463
Product name: 3-(Trifluoromethyl)benzaldehyde, 97%
Packaging: 5g
Price: $48.65
Updated: 2024/03/01

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3-(Trifluoromethyl)benzaldehyde Chemical Properties,Usage,Production

Uses

3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY ORANGE LIQUID

Uses

3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-╬│-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 426, 1946 DOI: 10.1021/ja01207a024

General Description

Aldol reaction of 3-(trifluoromethyl)benzaldehyde with hydroxyacetone in the aldolase antibody 38C2-ionic liquid system has been investigated.

3-(Trifluoromethyl)benzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

3-(3-Trifluoromethylphenyl)propionic acid

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3-(Trifluoromethyl)benzaldehyde Suppliers

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View Lastest Price from 3-(Trifluoromethyl)benzaldehyde manufacturers

Hebei Duling International Trade Co. LTD

Product: 3-(Trifluoromethyl)benzaldehyde 454-89-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 Ton
Release date: 2022-11-14

Hebei Kingfiner Technology Development Co. , Ltd.

Product: 3-(Trifluoromethyl)benzaldehyde 454-89-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000kg
Release date: 2023-10-31

Hebei Fengqiang Trading Co., LTD

Product: 3-(Trifluoromethyl)Benzaldehyde 454-89-7
Price: US $100.00/drum
Min. Order: 1drum
Purity: 99
Supply Ability: 5000
Release date: 2023-09-07

454-89-7, 3-(Trifluoromethyl)benzaldehydeRelated Search:

2-Methylbenzotrifluoride Benzaldehyde 3-Aminobenzotrifluoride 2-(Trifluoromethyl)benzoic acid (Trifluoromethyl)trimethylsilane 3-(Trifluoromethyl)anisole 3-(Trifluoromethyl)benzoyl chloride 3-Trifluoromethylphenol 3-(Trifluoromethyl)phenylacetone 3-(Trifluoromethyl)benzoic acid Trifluoromethanesulfonic acid p-Tolualdehyde 4-(Trifluoromethoxy)benzaldehyde 4-(Trifluoromethyl)benzoic acid alpha,alpha,alpha-Trifluoro-o-toluoyl chloride 4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID 1-NAPHTHALEN-2-YL-ETHYLAMINE 3-(3-METHYLPHENYL)PROPIONIC ACID

m-Trifluoromethoxy benzaldehyde

3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-3-tolualdehyde

Alpha-Trifluoro-M-tolualdehyde

3-(TrifluoroMethyl)benzaldehyde, 97% 25GR

3-(TrifluoroMethyl)benzaldehyde, 97% 5GR

3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-m-tolualdehyde

3-(three fluoroMethyl)benzeneforMaldehyde

Between the three groups in benzene forMaldehyde

alpha,alpha,alpha-Trifluoro-m-toluylaldehyde

3-TRIFLUORMETHYLBENZALDEHYDE

3-(TRIFLUOROMETHYL)BENZALDEHYDE

A,A,A-TRIFLUORO-3-TOLUALDEHYDE

A,A,A-TRIFLUORO-M-TOLUALDEHYDE

alpha,alpha,alpha-Trifluoro-3-tolualdehyde

ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUALDEHYDE

Cinacalcet Impurity 56

BENZOTRIFLUORIDE-3-CARBALDEHYDE

MTF-BAD

M-TRIFLUOROMETHYLBENZALDEHYDE

3-(trifluoromethyl)-benzaldehyd

m-Tolualdehyde, alpha,alpha,alpha-trifluoro-

m-Trifluoromethylbenzaldehyde 3-Trifluoromethyl Benzaldehyde

3-TRIFLUOROMETHYLBENZYLDEHYDE

m-Trifluoromethylbenzaldehyde,97%

à,à,à-trifluoro-m-tolualdehyde

3-(Trifluoromethyl)benzaldehyde98%

A,A,A-TRIFLUORO-META-TOLUALDEHYDE

ALPHA,ALPHA,ALPHA-TRIFLUORO-META-TOLUALDEHYDE

α,α,α-Trifluoro-m-toluylaldehyde

m-Trifuoromethylbenzaldehyde

Benzaldehyde, 3-(trifluoromethyl)-

3-(Trifluoromethyl)benzaldehyde,97%

3-(three fluoroMethyl

3-(Trifluorzomethyl)Benzaldehyde

trifluoromethylbenzaldehyde-13C6

454-89-7

455-89-7

454-89-1

454-89-71

455-89-7

C8H5F3O

ALDEHYDE

Organic Building Blocks

Aldehydes

Building Blocks

Carbonyl Compounds

C8

Benzotrifluoride Series

Aromatic Aldehydes & Derivatives (substituted)

Benzaldehyde

3-(Trifluoromethyl)benzaldehyde

bc0001