4-(Trifluoromethyl)benzoic acid

Uses

Product Name: 4-(Trifluoromethyl)benzoic acid
CAS No.: 455-24-3
Chemical Name: 4-(Trifluoromethyl)benzoic acid
Synonyms: PTF;PTF-BOA;C 71640;p-benzoic Acid;RARECHEM AL BO 0066;TIMTEC-BB SBB008571;p-Trifluoromethylbenzoic;P-CARBOXYBENZOTRIFLUORIDE;4-CARBOXYBENZOTRIFLUORIDE;P-TRIFLUOROMETHYLBENZOIC ACID
CBNumber: CB7377273
Molecular Formula: C8H5F3O2
Formula Weight: 190.12
MOL File: 455-24-3.mol

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4-(Trifluoromethyl)benzoic acid Property

Melting point:: 219-220 °C(lit.)
Boiling point:: 247°C 753mm
Density: 1.3173 (estimate)
Flash point:: 247°C/753mm
storage temp.: Sealed in dry,Room Temperature
pka: 3.69±0.10(Predicted)
form: Fine Crystalline Powder
color: White to slight gray
Water Solubility: Soluble in water.
BRN: 2049241
InChI: InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13)
InChIKey: SWKPKONEIZGROQ-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC=C(C(F)(F)F)C=C1
CAS DataBase Reference: 455-24-3(CAS DataBase Reference)
NIST Chemistry Reference: «ALPHA»,«alpha»,«alpha»-trifluoro-p-toluic acid(455-24-3)
EPA Substance Registry System: Benzoic acid, 4-(trifluoromethyl)- (455-24-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37-24/25
WGK Germany: 3
TSCA: T
HazardClass: IRRITANT
HS Code: 29163900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196894
Product name: 4-(Trifluoromethyl)benzoic acid
Purity: 98%
Packaging: 5g
Price: $60.42
Updated: 2025/07/31

TCI Chemical

Product number: T1145
Product name: 4-(Trifluoromethyl)benzoic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $45
Updated: 2025/07/31

TCI Chemical

Product number: T1145
Product name: 4-(Trifluoromethyl)benzoic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $134
Updated: 2025/07/31

TRC

Product number: T895970
Product name: 4-(Trifluoromethyl)benzoic acid
Packaging: 1g
Price: $45
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK146612
Product name: 4-(Trifluoromethyl)benzoic acid
Purity: 99%
Packaging: 100g
Price: $556
Updated: 2021/12/16

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4-(Trifluoromethyl)benzoic acid Chemical Properties,Usage,Production

Uses

4-(Trifluoromethyl)benzaldehyde is a reactant that has been used in the preparation of N,N'-(Arylmethylene)bisamides with cytotoxic activity as anti cancer agents.

Chemical Properties

White to light yellow crystal powde

Uses

4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates via?N,N?-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

Definition

ChEBI: A benzoic acid carrying a 4-trifluoromethyl substituent.

4-(Trifluoromethyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

4-(TRIFLUOROMETHYL)PHENYL ISOCYANATE

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4-(Trifluoromethyl)benzoic acid Suppliers

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View Lastest Price from 4-(Trifluoromethyl)benzoic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-(Trifluoromethyl)benzoic acid 455-24-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-31

Speranza Chemical Co., Ltd.

Product: 4-(Trifluoromethyl) benzoic acid 455-24-3
Price: US $45.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 300MT/year
Release date: 2019-12-24

Henan Aochuang Chemical Co.,Ltd.

Product: 4-(Trifluoromethyl)benzoic acid 455-24-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

455-24-3, 4-(Trifluoromethyl)benzoic acidRelated Search:

o-Toluic acid 4-Bromomethylbenzoic acid 4-(Chloromethyl)benzoic acid Ethyl 2-(Chlorosulfonyl)acetate alpha,alpha,alpha-Trifluoro-o-toluoyl chloride p-Toluic acid Folic acid 3-(Trifluoromethyl)anisole m-Toluic acid 2,3,4-Trifluorobenzoic acid Methyl 4-trifluoromethylbenzoate 4-(Aminomethyl)benzoic acid 3-(Trifluoromethyl)benzaldehyde 2-(Trifluoromethyl)benzaldehyde 4-(Trifluoromethyl)benzylamine Citric acid α-Lipoic Acid 4-(TRIFLUOROMETHOXY)BENZOYL CHLORIDE

4-(trifluoromethyl)-benzoicaci

Benzoic acid, 4-(trifluoromethyl)-

4-(TRIFLUOROMETHYL)BENZOIC ACID

A,A,A-TRIFLUORO-P-TOLUIC ACID

ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLUIC ACID

PTF-BOA

P-TRIFLUOROMETHYLBENZOIC ACID

RARECHEM AL BO 0066

P-CARBOXYBENZOTRIFLUORIDE

TIMTEC-BB SBB008571

p-Trifluoromethylbenzoic

p-Trifluoromethylbenzoicacid,min.98%

à,à,à-trifluoro-p-toluic acid

α,α,α-trifluoro-p-toluic acid

4-(Trifluoromethyl)benzoicacid98%

4-CARBOXYBENZOTRIFLUORIDE

p-Trifluoromethylbenzoic Acid 4-Trifluoromethylbenzoic Acid

4-TRIFLUOROMETHYL BENZOIC ACID FINE GRADE

4-TRIFLUOROMETHYL BENZOIC ACID TECHNICAL GRADE

α,α,α-Trifluoro-p-toluic acid, 4-Carboxybenzotrifluoride

C 71640

4-(Trifluoromethyl)benzoic acid ,99%

p-Trifluoromethylbenzoic acid, min. 98%

p-benzoic Acid

Alpha-Trifluoro-p-toluic acid

4-Carboxybenzotrifluoride, alpha,alpha,alpha-Trifluoro-p-toluic acid

4- threefluorine Methyl benzoic acid

The three fluorinated Methyl benzoic acid

PTF

CAS No.455-24-3 4-(Trifluoromethyl)benzoic acid

4-methyl-N'-(4- (trifluoromethyl)benzylidene)benzenesulfonohydrazide

4-(Trifluoromethyl)benzoic acid , 4-(Trifluoromethyl)benzoic acid

455-24-3

455-24-31

Organic Building Blocks

CARBOXYLIC ACID

Carboxylic Acids

Carbonyl Compounds

C8

Building Blocks

Benzotrifluoride Series

Carboxylic Acids

Phenyls & Phenyl-Het

blocks

Carboxes

Boronic Acid series

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Carboxylic Acids

Phenyls & Phenyl-Het

API intermediates

bc0001