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o-Toluic acid

Product Name
o-Toluic acid
CAS No.
118-90-1
Chemical Name
o-Toluic acid
Synonyms
o-toluic;uic acid;2-TOLUIC ACID;O-TOLUIC ACID;o-Totuic acid;O-TOLUYLIC ACID;o-ToluicAcid>o-Methylbenzoate;2-ToluicAcid98+%;2-methylbenzoate
CBNumber
CB5852905
Molecular Formula
C8H8O2
Formula Weight
136.15
MOL File
118-90-1.mol
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o-Toluic acid Property

Melting point:
102-104 °C (lit.)
Boiling point:
258-259 °C (lit.)
Density 
1.062 g/mL at 25 °C (lit.)
refractive index 
1.512
Flash point:
148 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
1.2g/l
pka
3.91(at 25℃)
form 
Needle-Like Crystalline Solid
color 
White to slightly yellow
Specific Gravity
1.062
PH
3.1 (H2O, 20℃)(saturated aqueous solution)
Water Solubility 
<0.1 g/100 mL at 19 ºC
Merck 
14,9535
BRN 
1072103
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
InChIKey
ZWLPBLYKEWSWPD-UHFFFAOYSA-N
CAS DataBase Reference
118-90-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 2-methyl-(118-90-1)
EPA Substance Registry System
o-Toluic acid (118-90-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-22
WGK Germany 
3
RTECS 
XU1400000
TSCA 
Yes
HS Code 
29163900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T36404
Product name
o-Toluic acid
Purity
99%
Packaging
100g
Price
$38.5
Updated
2021/12/16
Sigma-Aldrich
Product number
T36404
Product name
o-Toluic acid
Purity
99%
Packaging
500g
Price
$75.1
Updated
2021/12/16
TCI Chemical
Product number
T0292
Product name
o-Toluic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$18
Updated
2021/12/16
TCI Chemical
Product number
T0292
Product name
o-Toluic Acid
Purity
>98.0%(T)
Packaging
100g
Price
$33
Updated
2021/12/16
Alfa Aesar
Product number
A13856
Product name
o-Toluic acid, 98+%
Packaging
250g
Price
$24.6
Updated
2021/12/16
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o-Toluic acid Chemical Properties,Usage,Production

Chemical Properties

White crystals. Slightly soluble in water; soluble in alcohol and chloroform. Combustible.

Uses

Bacteriostat.

Uses

o-Toluic acid is part of a group of Benzoic acid (B203900) derivatives that possess inhibitory activity against mushroom tyrosinases. o-Toluic acid is also used as a reagent to synthesize halogen-substituted benzoic acids (such as 2,4-Dichlorobenzoic acid [D431955]), which have potential muscle stimulating effects.

Definition

ChEBI: A methylbenzoic acid that is benzoic acid substituted by a methyl group at position 2.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 2, p. 588, 1943
The Journal of Organic Chemistry, 25, p. 616, 1960 DOI: 10.1021/jo01074a035
Tetrahedron Letters, 22, p. 1013, 1981 DOI: 10.1016/S0040-4039(01)82853-7

Air & Water Reactions

Fine dust dispensed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. . Insoluble in water.

Reactivity Profile

o-Toluic acid is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in o-Toluic acid to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions. o-Toluic acid is incompatible with strong oxidizers.

Fire Hazard

Flash point data for o-Toluic acid are not available. o-Toluic acid is probably combustible. Fine dust dispensed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.

Purification Methods

Crystallise the acid from *benzene (2.5mL/g) and dry in air. The S-benzylisothiuronium salt has m 146o (from aqueous EtOH). [Beilstein 9 IV 1697.]

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o-Toluic acid Suppliers

Taizhou Chemedir Biopharm-tech. Co., Ltd
Tel
0523-86200218
Fax
+86 523-86200613
Email
sale1_cmd@chemedir.com
Country
China
ProdList
110
Advantage
64
Tianjin Englon Technology Co., LTD
Tel
010-1234567
Email
2062435649@qq.com
Country
China
ProdList
105
Advantage
49
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 qq:2355568890
Fax
0086-21-50182339
Email
sales@demochem.com; export1@demochem.com
Country
China
ProdList
2582
Advantage
57
Beijing dtftchem Technology Co., Ltd.
Tel
13651141086; 86(10)60275028、60275820
Fax
86 (10) 60270825
Email
dtftchem@sina.com
Country
China
ProdList
3392
Advantage
62
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
sales.gd@hwrkchemical.com
Country
China
ProdList
17295
Advantage
55
Energy Chemical
Tel
021-58432009-
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
43431
Advantage
61
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View Lastest Price from o-Toluic acid manufacturers

Asia Chem I and E (Jiangsu) Co Ltd
Product
O-Toluic acid 118-90-1
Price
US $6.20/Kg/Drum
Min. Order
25Kg/Drum
Purity
99.0%min
Supply Ability
60tons/month
Release date
2021-10-19
Wuhan wingroup Pharmaceutical Co., Ltd
Product
o-Toluic acid 118-90-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99.9%
Supply Ability
100MT/Month
Release date
2021-07-12
Wuhan wingroup Pharmaceutical Co., Ltd
Product
2-Methylbenzoic acid 118-90-1
Price
US $10.00/g
Min. Order
100g
Purity
99%
Supply Ability
1000Ton/Month
Release date
2021-07-09

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