o-Toluic acid

Product Name: o-Toluic acid
CAS No.: 118-90-1
Chemical Name: o-Toluic acid
Synonyms: 2-METHYLBENZOIC ACID;o-toluic;o-Totuic acid;ORTHO-TOLUIC ACID;uic acid;2-TOLUIC ACID;O-TOLUIC ACID;0-Toluic acid;O-TOLUYLIC ACID;o-ToluicAcid>
CBNumber: CB5852905
Molecular Formula: C8H8O2
Formula Weight: 136.15
MOL File: 118-90-1.mol

More

Less

o-Toluic acid Property

Melting point:: 102-104 °C (lit.)
Boiling point:: 258-259 °C (lit.)
Density: 1.062 g/mL at 25 °C (lit.)
refractive index: 1.512
Flash point:: 148 °C
storage temp.: Sealed in dry,Room Temperature
solubility: 1.2g/l
form: Needle-Like Crystalline Solid
pka: 3.91(at 25℃)
Specific Gravity: 1.062
color: White to slightly yellow
PH: 3.1 (H2O, 20℃)(saturated aqueous solution)
Water Solubility: <0.1 g/100 mL at 19 ºC
Merck: 14,9535
BRN: 1072103
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
InChIKey: ZWLPBLYKEWSWPD-UHFFFAOYSA-N
CAS DataBase Reference: 118-90-1(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-methyl-(118-90-1)
EPA Substance Registry System: o-Toluic acid (118-90-1)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36-22
WGK Germany: 3
RTECS: XU1400000
TSCA: Yes
HS Code: 29163900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T36404
Product name: o-Toluic acid
Purity: 99%
Packaging: 100g
Price: $63.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: T36404
Product name: o-Toluic acid
Purity: 99%
Packaging: 500g
Price: $121
Updated: 2024/03/01

TCI Chemical

Product number: T0292
Product name: o-Toluic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $43
Updated: 2024/03/01

TCI Chemical

Product number: T0292
Product name: o-Toluic Acid
Purity: >98.0%(T)
Packaging: 100g
Price: $77
Updated: 2024/03/01

Alfa Aesar

Product number: A13856
Product name: o-Toluic acid, 98+%
Packaging: 250g
Price: $29.65
Updated: 2024/03/01

More

Less

o-Toluic acid Chemical Properties,Usage,Production

Chemical Properties

White crystals. Slightly soluble in water; soluble in alcohol and chloroform. Combustible.

Uses

Bacteriostat.

Uses

o-Toluic acid is part of a group of Benzoic acid (B203900) derivatives that possess inhibitory activity against mushroom tyrosinases. o-Toluic acid is also used as a reagent to synthesize halogen-substituted benzoic acids (such as 2,4-Dichlorobenzoic acid [D431955]), which have potential muscle stimulating effects.

Definition

ChEBI: A methylbenzoic acid that is benzoic acid substituted by a methyl group at position 2.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 2, p. 588, 1943
The Journal of Organic Chemistry, 25, p. 616, 1960 DOI: 10.1021/jo01074a035
Tetrahedron Letters, 22, p. 1013, 1981 DOI: 10.1016/S0040-4039(01)82853-7

Air & Water Reactions

Fine dust dispensed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. . Insoluble in water.

Reactivity Profile

o-Toluic acid is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in o-Toluic acid to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions. o-Toluic acid is incompatible with strong oxidizers.

Fire Hazard

Flash point data for o-Toluic acid are not available. o-Toluic acid is probably combustible. Fine dust dispensed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.

Purification Methods

Crystallise the acid from *benzene (2.5mL/g) and dry in air. The S-benzylisothiuronium salt has m 146o (from aqueous EtOH). [Beilstein 9 IV 1697.]

o-Toluic acid Preparation Products And Raw materials

Raw materials

o-Xylene Cobalt naphthenate

Preparation Products

Ethametsulfuron-methyl 2-BENZYL-2,3-DIHYDROISOQUINOLIN-4(1H)-ONE HYDROCHLORIDE 2-(Bromomethyl)benzoic acid Bensulfuron methyl Sulfometuron-methyl Tribenuron methyl o-Toluoyl chloride N-METHYL-N-(2-METHYLBENZYL)AMINE 2-METHYLBENZANILIDE Mepronil m-Cresol o-Tolunitrile METSULFURON METHYL

More

Less

o-Toluic acid Suppliers

Belgium 1 Canada 2 China 447 Europe 4 France 1 Germany 9 India 47 Japan 5 Norway 1 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 2 Ukraine 2 United Kingdom 7 United States 54 Global 587

TCI Chemicals (India) Pvt. Ltd.

Tel: --
Fax: --
Email: sales-in@tcichemicals.com
Country: India
ProdList: 6768
Advantage: 58

Sisco Research Laboratories Pvt. Ltd.

Tel: --
Fax: --
Email: marketing@srlchem.com
Country: India
ProdList: 4315
Advantage: 58

Triveni chemicals

Tel: --
Fax: --
Email: sales@trivenichemical.com
Country: India
ProdList: 6088
Advantage: 58

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: India
ProdList: 6905
Advantage: 58

Sisco Resech Laboratories Private Limited

Tel: --
Fax: --
Country: India
ProdList: 655
Advantage: 58

Trignokem International.

Tel: --
Fax: --
Email: ignokem@gmail.com
Country: India
ProdList: 233
Advantage: 58

Oxford laboratories

Tel: --
Fax: --
Country: India
ProdList: 652
Advantage: 58

Trignokem International

Tel: --
Fax: --
Country: India
ProdList: 110
Advantage: 58

Artchem Enterprises.

Tel: --
Fax: --
Email: info@artchemindia.com
Country: India
ProdList: 18
Advantage: 58

Ujwal Pharma Pvt., Ltd.

Tel: --
Fax: --
Email: ujwalpharma@vsnl.com
Country: India
ProdList: 10
Advantage: 58

Ashok Pharma Chem

Tel: --
Fax: --
Email: contact@ganeshremedies.com
Country: India
ProdList: 1
Advantage: 58

ASM Organics

Tel: --
Fax: --
Country: India
ProdList: 1185
Advantage: 58

S.D. Fine-Chem Limited (SDFCL)

Tel: --
Fax: --
Email: managermumbai@sdfcl.net
Country: India
ProdList: 62
Advantage: 58

Mehta Enterprise

Tel: --
Fax: --
Country: India
ProdList: 155
Advantage: 58

Spectrochem Private Limited

Tel: --
Fax: --
Country: India
ProdList: 1055
Advantage: 58

S.Zhaveri Pharmakem Pvt. Ltd

Tel: --
Fax: --
Country: India
ProdList: 58
Advantage: 58

Molychem

Tel: --
Fax: --
Country: India
ProdList: 576
Advantage: 58

Loba Chemie Pvt., Ltd.

Tel: --
Fax: --
Email: @lobachemie.com
Country: India
ProdList: 765
Advantage: 58

Kaival Chemicals Pvt. Ltd.

Tel: --
Fax: --
Email: response@kaivalchemicals.com
Country: India
ProdList: 38
Advantage: 58

Multichem Specialities Private Limited.

Tel: --
Fax: --
Email: sales@multichemindia.com
Country: India
ProdList: 127
Advantage: 58

Oceanic Pharmachem Pvt., Ltd. (OPPL)

Tel: --
Fax: --
Email: info@oceanicpharmachem.com
Country: India
ProdList: 946
Advantage: 58

HiMedia Laboratories

Tel: --
Fax: --
Email: o@himedialabs.com
Country: India
ProdList: 1841
Advantage: 58

Clearsynth Labs

Tel: --
Fax: --
Email: fo@clearsynth.com
Country: India
ProdList: 3887
Advantage: 58

Navyug Pharmachem Private Limited

Tel: --
Fax: --
Country: India
ProdList: 9
Advantage: 58

Shiv Shakti Acid & Chemicals

Tel: --
Fax: --
Email: info@shivshaktiacid.com
Country: India
ProdList: 22
Advantage: 58

Avra Synthesis Pvt Ltd

Tel: --
Fax: --
Email: info@avrasynthesis.com
Country: India
ProdList: 1603
Advantage: 30

Loba Chemie Pvt Ltd

Tel: --
Fax: --
Country: India
ProdList: 498
Advantage: 58

Anand Agencies

Tel: --
Fax: --
Email: en@gmail.com
Country: India
ProdList: 2332
Advantage: 58

Delta Chemsol

Tel: --
Fax: --
Country: India
ProdList: 99
Advantage: 58

Kaival Chemicals Private Limited

Tel: --
Fax: --
Country: India
ProdList: 42
Advantage: 58

Ujwal Pharma Pvt. Ltd.

Tel: --
Fax: --
Country: India
ProdList: 8
Advantage: 58

Manav Biochem Impex Private Limited

Tel: --
Fax: --
Country: India
ProdList: 198
Advantage: 58

Astitva Chemicals

Tel: --
Fax: --
Country: India
ProdList: 89
Advantage: 58

Central Drug House(P) Ltd.

Tel: --
Fax: --
Email: sales@cdhfinechemical.com
Country: India
ProdList: 6157
Advantage: 58

LOBA CHEMIE PVT.LTD.

Tel: --
Fax: --
Email: info@lobachemie.com
Country: India
ProdList: 3075
Advantage: 58

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

Dr Prem's Molecules Pvt. Ltd.

Tel: --
Fax: --
Email: prem@dpmolecules.com
Country: India
ProdList: 544
Advantage: 50

CHEMSWORTH

Tel: --
Fax: --
Email: info@chemsworth.com
Country: India
ProdList: 6700
Advantage: 30

S. Nihar Exports

Tel: --
Fax: --
Email: nihar@giasbm01.vsnl.net.in
Country: India
ProdList: 232
Advantage: 50

ALPHA CHEMIKA

Tel: --
Fax: --
Email: info@exporterlabchemicals.com
Country: India
ProdList: 1679
Advantage: 43

Scientific OEM

Tel: --
Fax: --
Email: neeraj@scientificoem.com
Country: India
ProdList: 1994
Advantage: 38

More

Less

View Lastest Price from o-Toluic acid manufacturers

Anhui Royal Chemical Co., Ltd.

Product: O-TOLUIC ACID 118-90-1
Price: US $100.00/KG
Min. Order: 1000KG
Purity: 99.5%
Supply Ability: 20 TONS
Release date: 2024-05-22

Hebei Weibang Biotechnology Co., Ltd

Product: o-Toluic acid 118-90-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-24

airuikechemical co., ltd.

Product: Ortho toluic acid 118-90-1
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

118-90-1, o-Toluic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate Methyl 4-(bromomethyl)benzoate Methyl 4-methylbenzoate 4-HYDROXY-2-METHYLBENZOIC ACID 98 Methyl 2-(methylamino)benzoate 2-Iodobenzoic acid 2-Methoxybenzoic acid 2-Methyl-4-nitrobenzoic acid o-Tolunitrile 2-METHYL-6-NITROBENZOIC ACID 3-Methyl-4-nitrobenzoic acid Hyaluronic acid Citric acid Benzyl benzoate p-Toluic acid 3-Methyl-2-nitrobenzoic acid 2-Amino-5-methylbenzoic acid 3-Bromo-2-methylbenzoic acid

o-toluic

2-methyl-benzoicaci

Benzoicacid,2-methyl-

o-TOLUIC ACID pure

o-methyl benzoic acid，o-toluic acid

ORTHO TOLUIC ACID ( OTA )

O-Toluic acid ,99%

o-Toluic acid, 98+% 100GR

o-Toluic acid, 98+% 5GR

o-Toluic acid,2-Methylbenzoic acid

o-Toluic acid 99%

2-Methylbenzoic acid for synthesis

Alogliptin Related Compound 46

2-TOLUIC ACID

2-METHYLBENZOIC ACID

AKOS BBS-00003722

METHYLBENZOIC(O-) ACID

ORTHO-TOLUIC ACID

o-Methylbenzoate

O-METHYLBENZOIC ACID

O-TOLUYLIC ACID

O-TOLUIC ACID

RARECHEM AL BO 0033

2-Methylbenzoic Acid/o-Toluic acid

o-Totuic acid

O-ToluicAcidForSynthesis

2-ToluicAcid98+%

o-Toluic acid, 98+%

ORTHO-TOLUIC ACID FOR SYNTHESIS

o-Toluic acid118-90-1

2-methylbenzoate

uic acid

[Carbonyl-14C1]-toluic acid

[Phenyl-U-14C6]-toluic acid

o-ToluicAcid&gt

Tolvaptan Impurity 52

OTA，o-Toluic acid

o-Toluic acid ISO 9001：2015 REACH

High Pharmaceutical O-Toluic Acid 2-Methylbenzoic Acid CAS?118-90-1

o-Toluic Acid pure, 99.5%

Ortho Toluic Acid (2-Methyl Benzoic Acid)

0-Toluic acid

118-90-1

110-90-1

CH3C6H4COOH

118901

Organic Building Blocks

ARYL ACID

Carbonyl Compounds

Carboxylic Acids

C8

Building Blocks

Pyrazines ,Pyrans

intermediates

Organic acids