ChemicalBook > CAS DataBase List > 4-HYDROXY-2-METHYLBENZOIC ACID 98

4-HYDROXY-2-METHYLBENZOIC ACID 98

Product Name
4-HYDROXY-2-METHYLBENZOIC ACID 98
CAS No.
578-39-2
Chemical Name
4-HYDROXY-2-METHYLBENZOIC ACID 98
Synonyms
4-HYDROXY-2-METHYLBE;4-hydroxy-o-toluic acid;2-Methyl-4-hydroxybenzoic acid;4-Hydroxy-2-methylbenzoicAcid>Benzoic acid, 4-hydroxy-2-Methyl-;4-HYDROXY-2-METHYLBENZOIC ACID 98;4-Hydroxy-2-Methylbenzoic acid 98%;4-Hydroxy-o-toluic acid, 4-Carboxy-m-cresol;4-Hydroxy-2-Methyl benzoic acid/4-hydroxy-o-toluic acid
CBNumber
CB0498892
Molecular Formula
C8H8O3
Formula Weight
152.15
MOL File
578-39-2.mol
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4-HYDROXY-2-METHYLBENZOIC ACID 98 Property

Melting point:
177-181 °C
Boiling point:
339.1±30.0 °C(Predicted)
Density 
1.304±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
4.46±0.25(Predicted)
color 
White to Light yellow to Light orange
InChI
InChI=1S/C8H8O3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3,(H,10,11)
InChIKey
BBMFSGOFUHEVNP-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=C(O)C=C1C
CAS DataBase Reference
578-39-2
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26-39
WGK Germany 
2
HS Code 
29182900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
653160
Product name
4-Hydroxy-2-methylbenzoic acid
Purity
98%
Packaging
10g
Price
$155
Updated
2025/07/31
Sigma-Aldrich
Product number
653160
Product name
4-Hydroxy-2-methylbenzoic acid
Purity
98%
Packaging
1g
Price
$63
Updated
2023/06/20
TCI Chemical
Product number
H1311
Product name
4-Hydroxy-2-methylbenzoic Acid
Purity
>98.0%(GC)
Packaging
5g
Price
$53
Updated
2025/07/31
TCI Chemical
Product number
H1311
Product name
4-Hydroxy-2-methylbenzoic Acid
Purity
>98.0%(GC)
Packaging
25g
Price
$166
Updated
2025/07/31
TRC
Product number
H972645
Product name
4-Hydroxy-2-methylbenzoic acid
Packaging
250mg
Price
$55
Updated
2021/12/16
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4-HYDROXY-2-METHYLBENZOIC ACID 98 Chemical Properties,Usage,Production

Chemical Properties

White or pink crystalline powder

Definition

ChEBI: 4-hydroxy-2-methylbenzoic acid is a hydroxybenzoic acid.

Synthesis

6245-57-4

578-39-2

General procedure for the synthesis of 4-hydroxy-2-methylbenzoic acid from 4-methoxy-2-methylbenzoic acid: boron tribromide (20 mmol, 5 g, 10 eq.) was slowly added to a solution of 4-methoxy-2-methylbenzoic acid (2 mmol, 0.332 g) in dichloromethane (20 mL) under argon protection. The reaction mixture was stirred at room temperature until high performance liquid chromatography (HPLC) analysis showed complete consumption of the feedstock. Subsequently, 0.1 M hydrochloric acid (20 mL) was added to the reaction system to quench the reaction and the insoluble material was removed by filtration. The aqueous phase was concentrated under reduced pressure and the residue was dissolved in methanol and concentrated again under reduced pressure to remove the solvent. This dissolution-concentration process was repeated three times, resulting in purified 4-hydroxy-2-methylbenzoic acid as a yellow solid (0.24 g, 80% yield).

References

[1] European Journal of Organic Chemistry, 2008, # 5, p. 816 - 825
[2] Patent: WO2006/64286, 2006, A1. Location in patent: Page/Page column 93-94
[3] Patent: WO2007/144379, 2007, A1. Location in patent: Page/Page column 39
[4] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987, vol. 26, p. 679 - 682
[5] Patent: WO2006/79099, 2006, A2. Location in patent: Page/Page column 68; 69

4-HYDROXY-2-METHYLBENZOIC ACID 98 Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXY-2-METHYLBENZOIC ACID 98 Suppliers

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View Lastest Price from 4-HYDROXY-2-METHYLBENZOIC ACID 98 manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
4-HYDROXY-2-METHYLBENZOIC ACID 578-39-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-09-08
Shaanxi Dideu New Materials Co. Ltd
Product
4-HYDROXY-2-METHYLBENZOIC ACID 98 578-39-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-12
Changzhou waston chemical technology Co.,Ltd
Product
4-HYDROXY-2-METHYLBENZOIC ACID 98 578-39-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
follow your request
Release date
2023-06-01

578-39-2, 4-HYDROXY-2-METHYLBENZOIC ACID 98Related Search:


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