2-Bromo-3-methylbenzoic acid
- Product Name
- 2-Bromo-3-methylbenzoic acid
- CAS No.
- 53663-39-1
- Chemical Name
- 2-Bromo-3-methylbenzoic acid
- Synonyms
- Fluralaner-030;2-Bromo-3-methyl;2-Bromo-3-methylbenz;2-Bromo-m-toluic acid;Fluralaner Impurity 51;2-Bromo-3-carboxytoluene;2-Bromo-3-methylbenzoicaci;2-BROMO-3-METHYLBENZOIC ACID;3-methyl-2-bromobenzoic acid;2-Bromo-m-toluic acid (COOH=1)
- CBNumber
- CB5240535
- Molecular Formula
- C8H7BrO2
- Formula Weight
- 215.04
- MOL File
- 53663-39-1.mol
2-Bromo-3-methylbenzoic acid Property
- Melting point:
- 135-138 °C (lit.)
- Boiling point:
- 308.3±30.0 °C(Predicted)
- Density
- 1.599±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- Powder
- pka
- 2.92±0.10(Predicted)
- color
- Off-white
- CAS DataBase Reference
- 53663-39-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-37-26
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 560219
- Product name
- 2-Bromo-3-methylbenzoic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $29.1
- Updated
- 2023/06/20
- Product number
- 560219
- Product name
- 2-Bromo-3-methylbenzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $54.9
- Updated
- 2023/06/20
- Product number
- B3636
- Product name
- 2-Bromo-3-methylbenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $18
- Updated
- 2025/07/31
- Product number
- B3636
- Product name
- 2-Bromo-3-methylbenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $69
- Updated
- 2025/07/31
- Product number
- B697013
- Product name
- 2-Bromo-3-methylbenzoic Acid
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
2-Bromo-3-methylbenzoic acid Chemical Properties,Usage,Production
Chemical Properties
Off-white powder
Uses
2-Bromo-3-methylbenzoic acid may be used to synthesize N-phenyl-3-methylanthranilic acid via copper-catalyzed amination reaction with aniline.
General Description
2-Bromo-4-nitrotoluene is formed as an intermediate during the synthesis of 2-bromo-3-methylbenzoic acid. 2-Bromo-3-methylbenzoic acid can be obtained from 2-bromo-4-nitrotoluene via Von-Richter reaction.
Synthesis
4389-45-1
53663-39-1
The general procedure for synthesizing 2-bromo-3-methylbenzoic acid from 2-amino-3-methylbenzoic acid was as follows: referring to Example 1 (0142), 1.00 g of 2-amino-3-methylbenzoic acid, 8 mL of acetic acid, 4 mL of 50% hydrobromic acid, and 16 mL of water were mixed, followed by the addition of 0.46 g of sodium nitrite and 3 mL of water chilled on ice. After stirring the mixture in an ice bath for 10 minutes, the complete reaction of 2-amino-3-methylbenzoic acid was confirmed by silica gel thin layer chromatography (Spreader: hexane/ethyl acetate = 1/1, Rf value of 0.67 for 2-amino-3-methylbenzoic acid). Next, 1.42 g of copper bromide and 5 mL of water were added and the mixture was heated and reacted at 50 °C for 3 hours. Upon completion of the reaction, water was added to the mixture and the precipitate was collected by filtration to give 1.0 g of 2-bromo-3-methylbenzoic acid. (0143) 1H-NMR (CDCl3) δ (ppm): 2.49 (3H, s), 7.29 (1H, t, J=7.6Hz), 7.42 (1H, d, J=7.2Hz), 7.70 (1H, t, J=3.9Hz).
References
[1] Patent: US2017/57935, 2017, A1. Location in patent: Paragraph 0142; 0143
2-Bromo-3-methylbenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-3-methylbenzoic acid Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
View Lastest Price from 2-Bromo-3-methylbenzoic acid manufacturers
- Product
- 2-Bromo-3-methylbenzoic acid 53663-39-1
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-10