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4-(Aminomethyl)benzoic acid

Description References
Product Name
4-(Aminomethyl)benzoic acid
CAS No.
56-91-7
Chemical Name
4-(Aminomethyl)benzoic acid
Synonyms
Tranexamic EP Impurity D;PAMBA;H-(4)AMBZ-OH;Chrisma Pereira;Aminomethyl Acid;Aninomethylbenzoicacid;AMINOMETHYL BENZOIC ACID;AMinoMethyl benzoic acid on;Tranexamic Acid EP Impurity D;Benzoic acid, 4-(aMinoMethyl)-
CBNumber
CB7742381
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
56-91-7.mol
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4-(Aminomethyl)benzoic acid Property

Melting point:
≥300 °C (lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated)
pka
3.75±0.10(Predicted)
form 
Powder
color 
White to almost white
Water Solubility 
Slightly soluble in water. Insoluble in ethanol, benzene and chloroform.
BRN 
1100606
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
QCTBMLYLENLHLA-UHFFFAOYSA-N
CAS DataBase Reference
56-91-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-26,37/39
WGK Germany 
3
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
283746
Product name
4-(Aminomethyl)benzoic acid
Purity
97%
Packaging
5g
Price
$46.9
Updated
2024/03/01
Sigma-Aldrich
Product number
283746
Product name
4-(Aminomethyl)benzoic acid
Purity
97%
Packaging
25g
Price
$108
Updated
2024/03/01
TCI Chemical
Product number
A0965
Product name
4-(Aminomethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
A0965
Product name
4-(Aminomethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
100g
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
B23519
Product name
4-(Aminomethyl)benzoic acid, 97%
Packaging
25g
Price
$78.65
Updated
2024/03/01
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4-(Aminomethyl)benzoic acid Chemical Properties,Usage,Production

Description

4-(Aminomethyl)benzoic acid is a organic compound that can serve as a type 2 antifibrinolytic agent used in the treatment of fibrotic skin disorders, such as Peyronie's disease. It is believed that 4-(Aminomethyl)benzoic acid is effective to increase the oxygen uptake at the tissue level and enhance activity of monoamine oxidase, thus to promote the degradation of serotonin, which in excess, may lead to fibrotic changes. It is also administrated by mouth to treat several skin conditions including vitiligo, pemphigus, dermatomyositis, morphea, lymphoblastoma cutis and scleroderma. It is sometimes used in pill form by patients suffering from irritable bowel syndrome to treat the relevant gastrointestinal symptoms and applied in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels. Besides, it can also serve as nutritional supplements to darken gray hair, prevent hair loss, make skin look younger and prevent sunburn and its benefits are claimed for people with fatigue, irritability, depression, weeping eczema, scleroderma, patchy pigment loss in skin, and premature grey hair.

References

https://en.wikipedia.org/wiki/4-Aminobenzoic_acid
https://www.alfa.com/en/catalog/B23519/
https://pubchem.ncbi.nlm.nih.gov/compound/4-aminobenzoic_acid#section=Top
http://www.webmd.com/vitamins-supplements/ingredientmono-1004-PABA+PARA-AMINOBENZOIC+ACID+PABA.aspxactiveIngredientId=1004&activeIngredientName=PABA

Chemical Properties

white to light yellow crystal powde

Uses

4-(Aminomethyl)benzoic acid acts as an unnatural amino acid derivative. It is also used as a type 2 antifibrinolytic agent. Further, it reacts with 2-methyl-isothiourea sulfate to prepare 4-guanidinomethylbenzoic acid.

Uses

4-(Aminomethyl)benzoic acid (PAMBA) can be used in the synthesis of:

  • Cobalt carboxy phosphonates.
  • Apoptozole (Az), which has cellular potency to promote membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel activity.
  • Cyclopeptide composed of L-glutamic acid and 3-aminobenzoic acid that can be used as receptors for a variety of cations and anions.
  • A bioactive peptide which has potent GPR54 (a G protein-coupled receptor) agonistic activity.

Uses

4-(Aminomethyl)benzoic Acid is a type 2 antifibrinolytic agent.

Definition

ChEBI: Aminomethylbenzoic acid is a member of benzoic acids.

4-(Aminomethyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Aminomethyl)benzoic acid Suppliers

Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
yxinchem
Tel
+86-0710-4323688 +86-18071785587
Fax
15502706050
Email
market@yxinchem.com
Country
China
ProdList
1022
Advantage
58
Jinan Hongkangda Chemical Co., Ltd
Tel
0531-88901705 18753193522
Email
810353473@qq.com
Country
China
ProdList
137
Advantage
58
Suzhou dexuan New Material Technology Co., Ltd
Tel
13773006286
Email
siyzhxl@163.com
Country
China
ProdList
27
Advantage
58
Jinan Dexinjia Biological Technology Co., Ltd
Tel
0531-8237-5880 15098789112
Fax
0531-82375893
Email
2710825968@qq.com
Country
China
ProdList
807
Advantage
58
Nanjing hongshenghuo Biotechnology Co., Ltd
Tel
025-58311670 18020159086
Email
54604129@qq.com
Country
China
ProdList
139
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
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View Lastest Price from 4-(Aminomethyl)benzoic acid manufacturers

Jinan Finer Chemical Co., Ltd
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
500mt
Release date
2020-10-19
Anhui Ruihan Technology Co., Ltd
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-09-08
Henan Bao Enluo International TradeCo.,LTD
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $50.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000MT
Release date
2023-07-24

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