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ChemicalBook > CAS DataBase List > 4-(Aminomethyl)benzoic acid

4-(Aminomethyl)benzoic acid

Description References
Product Name
4-(Aminomethyl)benzoic acid
CAS No.
56-91-7
Chemical Name
4-(Aminomethyl)benzoic acid
Synonyms
Tranexamic EP Impurity D;PAMBA;H-(4)AMBZ-OH;Chrisma Pereira;Aminomethyl Acid;Aninomethylbenzoicacid;AMINOMETHYL BENZOIC ACID;AMinoMethyl benzoic acid on;Tranexamic Acid EP Impurity D;Benzoic acid, 4-(aMinoMethyl)-
CBNumber
CB7742381
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
56-91-7.mol
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4-(Aminomethyl)benzoic acid Property

Melting point:
≥300 °C (lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated)
pka
3.75±0.10(Predicted)
form 
Powder
color 
White to almost white
Water Solubility 
Slightly soluble in water. Insoluble in ethanol, benzene and chloroform.
BRN 
1100606
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
QCTBMLYLENLHLA-UHFFFAOYSA-N
CAS DataBase Reference
56-91-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-26,37/39
WGK Germany 
3
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
283746
Product name
4-(Aminomethyl)benzoic acid
Purity
97%
Packaging
5g
Price
$46.9
Updated
2024/03/01
Sigma-Aldrich
Product number
283746
Product name
4-(Aminomethyl)benzoic acid
Purity
97%
Packaging
25g
Price
$108
Updated
2024/03/01
TCI Chemical
Product number
A0965
Product name
4-(Aminomethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
A0965
Product name
4-(Aminomethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
100g
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
B23519
Product name
4-(Aminomethyl)benzoic acid, 97%
Packaging
25g
Price
$78.65
Updated
2024/03/01
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4-(Aminomethyl)benzoic acid Chemical Properties,Usage,Production

Description

4-(Aminomethyl)benzoic acid is a organic compound that can serve as a type 2 antifibrinolytic agent used in the treatment of fibrotic skin disorders, such as Peyronie's disease. It is believed that 4-(Aminomethyl)benzoic acid is effective to increase the oxygen uptake at the tissue level and enhance activity of monoamine oxidase, thus to promote the degradation of serotonin, which in excess, may lead to fibrotic changes. It is also administrated by mouth to treat several skin conditions including vitiligo, pemphigus, dermatomyositis, morphea, lymphoblastoma cutis and scleroderma. It is sometimes used in pill form by patients suffering from irritable bowel syndrome to treat the relevant gastrointestinal symptoms and applied in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels. Besides, it can also serve as nutritional supplements to darken gray hair, prevent hair loss, make skin look younger and prevent sunburn and its benefits are claimed for people with fatigue, irritability, depression, weeping eczema, scleroderma, patchy pigment loss in skin, and premature grey hair.

References

https://en.wikipedia.org/wiki/4-Aminobenzoic_acid
https://www.alfa.com/en/catalog/B23519/
https://pubchem.ncbi.nlm.nih.gov/compound/4-aminobenzoic_acid#section=Top
http://www.webmd.com/vitamins-supplements/ingredientmono-1004-PABA+PARA-AMINOBENZOIC+ACID+PABA.aspxactiveIngredientId=1004&activeIngredientName=PABA

Chemical Properties

white to light yellow crystal powde

Uses

4-(Aminomethyl)benzoic acid acts as an unnatural amino acid derivative. It is also used as a type 2 antifibrinolytic agent. Further, it reacts with 2-methyl-isothiourea sulfate to prepare 4-guanidinomethylbenzoic acid.

Uses

4-(Aminomethyl)benzoic acid (PAMBA) can be used in the synthesis of:

  • Cobalt carboxy phosphonates.
  • Apoptozole (Az), which has cellular potency to promote membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel activity.
  • Cyclopeptide composed of L-glutamic acid and 3-aminobenzoic acid that can be used as receptors for a variety of cations and anions.
  • A bioactive peptide which has potent GPR54 (a G protein-coupled receptor) agonistic activity.

Uses

4-(Aminomethyl)benzoic Acid is a type 2 antifibrinolytic agent.

Definition

ChEBI: Aminomethylbenzoic acid is a member of benzoic acids.

reaction suitability

reaction type: solution phase peptide synthesis

4-(Aminomethyl)benzoic acid Preparation Products And Raw materials

Raw materials

4-Aminobenzoic acid 4-(Chloromethyl)benzoic acid 4-Bromomethylbenzoic acid 4-Cyanobenzoic acid Potassium benzoate

Preparation Products

Tranexamic Acid
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View Lastest Price from 4-(Aminomethyl)benzoic acid manufacturers

Jinan Finer Chemical Co., Ltd
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
500mt
Release date
2020-10-19
Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-20
Wuhan Circle Star Chem-medical Technology Co.,Ltd
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98
Supply Ability
1000
Release date
2025-01-03

56-91-7, 4-(Aminomethyl)benzoic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate 3-Methyl-4-nitrobenzoic acid o-Toluic acid 2-Amino-5-methylbenzoic acid m-Toluic acid 3-Methyl-2-nitrobenzoic acid 4-(Chloromethyl)benzoic acid 3-Methylanthranilic acid 3-(Trifluoromethyl)benzoic acid Citric acid Folic acid 4-Bromomethylbenzoic acid 5-Methyl-2-nitrobenzoic acid p-Toluic acid 4-Aminosalicylic acid 4-Bromo-2-methylbenzoic acid Ascoric Acid 4-(aminomethyl)benzoic acid hydrochloride

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