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4-Bromomethylbenzoic acid

Product Name
4-Bromomethylbenzoic acid
CAS No.
6232-88-8
Chemical Name
4-Bromomethylbenzoic acid
Synonyms
4-(BROMOMETHYL)BENZOIC ACID;ALPHA-BROMO-P-TOLUIC ACID;4-Bromomethylbenzoic;ALPHA-BROMO-P-TOLUYLIC ACID;AKOS BBS-00006715;Eprosartan USP RC D;RARECHEM AL BO 0068;A-BROMO-P-TOLUIC ACID;á-Bromo-p-toluic acid;à-bromo-p-toluic acid
CBNumber
CB6317157
Molecular Formula
C8H7BrO2
Formula Weight
215.04
MOL File
6232-88-8.mol
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4-Bromomethylbenzoic acid Property

Melting point:
224-229 °C(lit.)
Boiling point:
252.95°C (rough estimate)
Density 
1.5313 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Store below +30°C.
form 
Crystalline Powder
pka
4.10±0.10(Predicted)
color 
White to beige
Water Solubility 
Soluble in water.
BRN 
1862870
InChIKey
CQQSQBRPAJSTFB-UHFFFAOYSA-N
CAS DataBase Reference
6232-88-8(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 4-(bromomethyl)- (6232-88-8)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
3261
WGK Germany 
3
19-21
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29163900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
159549
Product name
4-(Bromomethyl)benzoic acid
Purity
97%
Packaging
5g
Price
$51.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1238251
Product name
Eprosartan Related Compound D
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15mg
Price
$511
Updated
2024/03/01
TCI Chemical
Product number
B0845
Product name
4-(Bromomethyl)benzoic Acid
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$24
Updated
2024/03/01
TCI Chemical
Product number
B0845
Product name
4-(Bromomethyl)benzoic Acid
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$66
Updated
2024/03/01
Alfa Aesar
Product number
L03371
Product name
4-(Bromomethyl)benzoic acid, 97%
Packaging
5g
Price
$38.65
Updated
2024/03/01
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4-Bromomethylbenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to beige crystalline powder

Uses

4-(Bromomethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent.

Uses

4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

Uses

4-(Bromomethyl)benzoic acid was used in the chemical modification of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), second generation photosensitizer. It was also used in the synthesis of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

Purification Methods

Crystallise the acid from pKEst Me2CO. [Beilstein 9 IV 1745.]

4-Bromomethylbenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromomethylbenzoic acid Suppliers

Jinan Liheng Biotechnology Co., Ltd.
Tel
0531-18763987518 18763987518
Email
levi@lihengpharm.com
Country
China
ProdList
1792
Advantage
58
Shenyang Maud Pharmaceutical Technology Co., Ltd.
Tel
024-23982345
Email
1020788318@qq.com
Country
China
ProdList
2251
Advantage
58
Shanghai Finechem Biotechnology Co., Ltd.
Tel
15821337685
Email
hwh-chem@163.com
Country
China
ProdList
96
Advantage
58
Shandong Xinmuyuan Chemical Technology Co., Ltd
Tel
19105383610(微) 19105383610
Email
83809669@qq.com
Country
China
ProdList
255
Advantage
58
Changzhou Share Chemical Co., Ltd
Tel
0519-82619998
Fax
+86-519-82619997
Email
wu@sharechem.com
Country
China
ProdList
29
Advantage
54
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 4-Bromomethylbenzoic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-Bromomethylbenzoic acid 6232-88-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-12
Hebei Mojin Biotechnology Co., Ltd
Product
4-Bromomethylbenzoic acid 6232-88-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-27
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Bromomethylbenzoic acid 6232-88-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

6232-88-8, 4-Bromomethylbenzoic acidRelated Search:


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  • C8H6BrO2
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