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4-Bromomethylbenzoic acid

Product Name
4-Bromomethylbenzoic acid
CAS No.
6232-88-8
Chemical Name
4-Bromomethylbenzoic acid
Synonyms
4-(BROMOMETHYL)BENZOIC ACID;ALPHA-BROMO-P-TOLUIC ACID;4-Bromomethylbenzoic;ALPHA-BROMO-P-TOLUYLIC ACID;AKOS BBS-00006715;Eprosartan USP RC D;RARECHEM AL BO 0068;A-BROMO-P-TOLUIC ACID;á-Bromo-p-toluic acid;à-bromo-p-toluic acid
CBNumber
CB6317157
Molecular Formula
C8H7BrO2
Formula Weight
215.04
MOL File
6232-88-8.mol
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4-Bromomethylbenzoic acid Property

Melting point:
224-229 °C(lit.)
Boiling point:
252.95°C (rough estimate)
Density 
1.5313 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Store below +30°C.
form 
Crystalline Powder
pka
4.10±0.10(Predicted)
color 
White to beige
Water Solubility 
Soluble in water.
BRN 
1862870
InChIKey
CQQSQBRPAJSTFB-UHFFFAOYSA-N
CAS DataBase Reference
6232-88-8(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 4-(bromomethyl)- (6232-88-8)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
3261
WGK Germany 
3
19-21
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29163900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
159549
Product name
4-(Bromomethyl)benzoic acid
Purity
97%
Packaging
5g
Price
$51.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1238251
Product name
Eprosartan Related Compound D
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15mg
Price
$511
Updated
2024/03/01
TCI Chemical
Product number
B0845
Product name
4-(Bromomethyl)benzoic Acid
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$24
Updated
2024/03/01
TCI Chemical
Product number
B0845
Product name
4-(Bromomethyl)benzoic Acid
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$66
Updated
2024/03/01
Alfa Aesar
Product number
L03371
Product name
4-(Bromomethyl)benzoic acid, 97%
Packaging
5g
Price
$38.65
Updated
2024/03/01
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4-Bromomethylbenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to beige crystalline powder

Uses

4-(Bromomethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent.

Uses

4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

Uses

4-(Bromomethyl)benzoic acid was used in the chemical modification of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), second generation photosensitizer. It was also used in the synthesis of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

Purification Methods

Crystallise the acid from pKEst Me2CO. [Beilstein 9 IV 1745.]

4-Bromomethylbenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromomethylbenzoic acid Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from 4-Bromomethylbenzoic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-Bromomethylbenzoic acid 6232-88-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-12
Hebei Mojin Biotechnology Co., Ltd
Product
4-Bromomethylbenzoic acid 6232-88-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-27
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Bromomethylbenzoic acid 6232-88-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

6232-88-8, 4-Bromomethylbenzoic acidRelated Search:


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