ChemicalBook > CAS DataBase List > 4-HYDROXY-2-METHYLBENZOIC ACID 98
4-HYDROXY-2-METHYLBENZOIC ACID 98
- Product Name
- 4-HYDROXY-2-METHYLBENZOIC ACID 98
- CAS No.
- 578-39-2
- Chemical Name
- 4-HYDROXY-2-METHYLBENZOIC ACID 98
- Synonyms
- 4-HYDROXY-2-METHYLBE;4-hydroxy-o-toluic acid;2-Methyl-4-hydroxybenzoic acid;4-Hydroxy-2-methylbenzoicAcid>Benzoic acid, 4-hydroxy-2-Methyl-;4-HYDROXY-2-METHYLBENZOIC ACID 98;4-Hydroxy-2-Methylbenzoic acid 98%;4-Hydroxy-o-toluic acid, 4-Carboxy-m-cresol;4-Hydroxy-2-Methyl benzoic acid/4-hydroxy-o-toluic acid
- CBNumber
- CB0498892
- Molecular Formula
- C8H8O3
- Formula Weight
- 152.15
- MOL File
- 578-39-2.mol
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4-HYDROXY-2-METHYLBENZOIC ACID 98 Property
- Melting point:
- 177-181 °C
- Boiling point:
- 339.1±30.0 °C(Predicted)
- Density
- 1.304±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 4.46±0.25(Predicted)
- color
- White to Light yellow to Light orange
- InChI
- InChI=1S/C8H8O3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3,(H,10,11)
- InChIKey
- BBMFSGOFUHEVNP-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=C(O)C=C1C
- CAS DataBase Reference
- 578-39-2
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 653160
- Product name
- 4-Hydroxy-2-methylbenzoic acid
- Purity
- 98%
- Packaging
- 10g
- Price
- $155
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 653160
- Product name
- 4-Hydroxy-2-methylbenzoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $63
- Updated
- 2023/06/20
TCI Chemical
- Product number
- H1311
- Product name
- 4-Hydroxy-2-methylbenzoic Acid
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $53
- Updated
- 2025/07/31
TCI Chemical
- Product number
- H1311
- Product name
- 4-Hydroxy-2-methylbenzoic Acid
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $166
- Updated
- 2025/07/31
TRC
- Product number
- H972645
- Product name
- 4-Hydroxy-2-methylbenzoic acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
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4-HYDROXY-2-METHYLBENZOIC ACID 98 Chemical Properties,Usage,Production
Chemical Properties
White or pink crystalline powder
Definition
ChEBI: 4-hydroxy-2-methylbenzoic acid is a hydroxybenzoic acid.
Synthesis
6245-57-4
578-39-2
General procedure for the synthesis of 4-hydroxy-2-methylbenzoic acid from 4-methoxy-2-methylbenzoic acid: boron tribromide (20 mmol, 5 g, 10 eq.) was slowly added to a solution of 4-methoxy-2-methylbenzoic acid (2 mmol, 0.332 g) in dichloromethane (20 mL) under argon protection. The reaction mixture was stirred at room temperature until high performance liquid chromatography (HPLC) analysis showed complete consumption of the feedstock. Subsequently, 0.1 M hydrochloric acid (20 mL) was added to the reaction system to quench the reaction and the insoluble material was removed by filtration. The aqueous phase was concentrated under reduced pressure and the residue was dissolved in methanol and concentrated again under reduced pressure to remove the solvent. This dissolution-concentration process was repeated three times, resulting in purified 4-hydroxy-2-methylbenzoic acid as a yellow solid (0.24 g, 80% yield).
References
[1] European Journal of Organic Chemistry, 2008, # 5, p. 816 - 825
[2] Patent: WO2006/64286, 2006, A1. Location in patent: Page/Page column 93-94
[3] Patent: WO2007/144379, 2007, A1. Location in patent: Page/Page column 39
[4] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987, vol. 26, p. 679 - 682
[5] Patent: WO2006/79099, 2006, A2. Location in patent: Page/Page column 68; 69
4-HYDROXY-2-METHYLBENZOIC ACID 98 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-HYDROXY-2-METHYLBENZOIC ACID 98 manufacturers
Shenzhen Nexcon Pharmatechs Ltd.
- Product
- 4-HYDROXY-2-METHYLBENZOIC ACID 578-39-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-09-08
Shaanxi Dideu New Materials Co. Ltd
- Product
- 4-HYDROXY-2-METHYLBENZOIC ACID 98 578-39-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-12
Changzhou waston chemical technology Co.,Ltd
- Product
- 4-HYDROXY-2-METHYLBENZOIC ACID 98 578-39-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- follow your request
- Release date
- 2023-06-01
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