2-Iodobenzoic acid
- Product Name
- 2-Iodobenzoic acid
- CAS No.
- 88-67-5
- Chemical Name
- 2-Iodobenzoic acid
- Synonyms
- O-IODOBENZOIC ACID;2-IODO BENZONIC ACID;NSC 3772;usafek-572;USAF ek-572;'LGC' (4009);O-iodine acid;IodobenzoicAcid;2-lodhenxoieacid;2-iodo-benzoicaci
- CBNumber
- CB1126640
- Molecular Formula
- C7H5IO2
- Formula Weight
- 248.02
- MOL File
- 88-67-5.mol
2-Iodobenzoic acid Property
- Melting point:
- 160-162 °C(lit.)
- Boiling point:
- 313.9±25.0 °C(Predicted)
- Density
- 2.25
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Soluble in dimethyl sulfoxide and methanol
- pka
- 2.85(at 25℃)
- form
- Powder, Crystals or Flakes
- color
- Light yellow to orange-brown
- Water Solubility
- sparingly soluble
- Sensitive
- Light Sensitive
- Merck
- 14,5030
- BRN
- 1861406
- Stability:
- Stable. Incompatible with strong oxidizing agents, strong bases.
- InChIKey
- CJNZAXGUTKBIHP-UHFFFAOYSA-N
- CAS DataBase Reference
- 88-67-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzoic acid, 2-iodo-(88-67-5)
- EPA Substance Registry System
- Benzoic acid, 2-iodo- (88-67-5)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-37/38-41-36/37/38-20/21/22
- Safety Statements
- 26-39-24/25-22-36
- WGK Germany
- 3
- RTECS
- DH2975000
- Hazard Note
- Irritant
- TSCA
- T
- HazardClass
- IRRITANT, LIGHT SENSITIVE
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I7675
- Product name
- 2-Iodobenzoic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $28.4
- Updated
- 2024/03/01
- Product number
- 418463
- Product name
- 2-Iodobenzoic acid
- Purity
- ≥99%, purified by sublimation
- Packaging
- 1G
- Price
- $34.6
- Updated
- 2023/01/07
- Product number
- I0053
- Product name
- 2-Iodobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $26
- Updated
- 2024/03/01
- Product number
- I0053
- Product name
- 2-Iodobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 100g
- Price
- $73
- Updated
- 2024/03/01
- Product number
- A10563
- Product name
- 2-Iodobenzoic acid, 98+%
- Packaging
- 25g
- Price
- $23.65
- Updated
- 2024/03/01
2-Iodobenzoic acid Chemical Properties,Usage,Production
Description
2-iodobenzoic acid and its derivatives are important pharmaceutical and chemical raw materials, which are necessary for the synthesis of various high-iodine reagents. It is commonly used as a precursor for the synthesis of 2-Iodoxybenzoic acid (IBX) and Dess-Martin peridinane, which are used as mild oxidants. It is also used in Suziki reaction.
Chemical Properties
white crystal powder. Soluble in alcohol and ether, insoluble in water.
Uses
Reagent for detection of sulfhydryl groups in proteins. 2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.
Preparation
2-Iodobenzoic acid is obtained from Anthranilic acid by diazotization and substitution. Diazotization of Anthranilic acid with sodium nitrite in the presence of sulfuric acid, control the temperature below 10℃, filter the diazotization solution, add the mixture of potassium iodide and sulfuric acid, stir for 10min after addition, and boil. Filter, wash with sodium thiosulfate solution, 2-Iodobenzoic acid can be recrystallized from water.
Definition
ChEBI: An iodobenzoic acid with a single iodo substituent placed at the 2-position.
Synthesis Reference(s)
Journal of the American Chemical Society, 93, p. 4841, 1971 DOI: 10.1021/ja00748a029
Purification Methods
Crystallise the acid repeatedly from water and EtOH. Sublime it under vacuum at 100o. [Beilstein 9 IV 1030.]
2-Iodobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Iodobenzoic acid manufacturers
- Product
- 2-Iodobenzoic acid 88-67-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-16
- Product
- 2-Iodobenzoic acid 88-67-5
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-04-24
- Product
- 2-Iodobenzoic acid 88-67-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-08