Dess-Martin periodinane

Product Name: Dess-Martin periodinane
CAS No.: 87413-09-0
Chemical Name: Dess-Martin periodinane
Synonyms: DESS-MARTIN;Dess-Martin periodane;DESS-MARTIN REAGENT;PERIODINANE;DESS-MARTINE;1,1,1-TRIACETOXY-1,1-DIHYDRO-1,2-BENZIODOXOL-3(1H)-ONE;Dess-Martin periodinane,D M P, TAPI;3-oxo-1l5-benzo[d][1,2]iodaoxole-1,1,1(3H)-triyl triacetate;1,1,1-TRIS(ACETYLOXY)-1,1-DIHYDRO-1,2-BENZIODOXOL-3-(1H)-ONE;Martin's reagent
CBNumber: CB0776475
Molecular Formula: C13H13IO8
Formula Weight: 424.14
MOL File: 87413-09-0.mol

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Dess-Martin periodinane Property

Melting point:: 130-133 °C (lit.)
Boiling point:: 40 °C
Density: 1.369 g/mL at 25 °C
Flash point:: >221 °F
storage temp.: -20°C
solubility: Soluble in chloroform, acetone, acetonitrile and methylene chloride. Slightly soluble in ether and hexane.
form: Liquid
color: Colorless to light yellow
Sensitive: Light Sensitive
Merck: 14,2933
BRN: 4548207
Stability:: Light Sensitive
InChI: InChI=1S/C13H13IO8/c1-8(15)19-14(20-9(2)16,21-10(3)17)12-7-5-4-6-11(12)13(18)22-14/h4-7H,1-3H3
InChIKey: NKLCNNUWBJBICK-UHFFFAOYSA-N
SMILES: I1(OC(=O)C)(OC(=O)C)(OC(=O)C)OC(=O)C2C=CC=CC1=2
CAS DataBase Reference: 87413-09-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,O,Xi
Risk Statements: 22-36/37/38-40-8-20/21/22-44
Safety Statements: 26-36-36/37-24/25-23-17-45-36/37/39
RIDADR: UN 1593 6.1/PG 3
WGK Germany: 3
Hazard Note: Harmful/Light sensitive
TSCA: No
HazardClass: 5.1
PackingGroup: Ⅲ
HS Code: 29349990
Storage Class: 5.2 - Organic peroxides and self-reacting hazardous materials
Hazard Classifications: Eye Irrit. 2
Self-react. C
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H272May intensify fire; oxidizer

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P220Keep/Store away from clothing/…/combustible materials.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 274623
Product name: Dess-Martin periodinane
Purity: 97%
Packaging: 5g
Price: $140
Updated: 2025/07/31

Sigma-Aldrich

Product number: 274623
Product name: Dess-Martin periodinane
Purity: 97%
Packaging: 25g
Price: $668
Updated: 2025/07/31

TCI Chemical

Product number: D2045
Product name: Dess-Martin Periodinane
Purity: >95.0%(T)
Packaging: 1g
Price: $35
Updated: 2025/07/31

TCI Chemical

Product number: D2045
Product name: Dess-Martin Periodinane
Purity: >95.0%(T)
Packaging: 5g
Price: $106
Updated: 2025/07/31

Sigma-Aldrich

Product number: 559873
Product name: Dess-Martin periodinane solution
Purity: 0.3 M in methylene chloride
Packaging: 5ml
Price: $49.7
Updated: 2025/07/31

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Dess-Martin periodinane Chemical Properties,Usage,Production

Description

Dess-Martin periodinane (DMP) is a hypervalent iodine compound widely used as a mild reagent for the oxidation of primary/secondary alcohols to aldehydes/ketones; oxidation of amides into imides; the dehydrogenation of amines to nitriles, and disulfides to sulfones. It is also used to selectively oxidize alkenes to epoxides. This is a useful reaction for generating three-membered cyclic ethers. Additionally, DMP is used to oxidatively cleave 1,2-diols to form aldehydes or ketones and in the synthesis of lactones.

Chemical Properties

White Crystalline powder

Uses

Dess-Martin Periodinaneis a very usefulreagent used in the oxidation of primary alcohols to aldehydes and secondary alcohols to ketones.

Uses

Dess Martin periodinane is used to oxidize primary alcohols to aldehydes and secondary alcohols to ketones. It is also used as an oxidant for complexes with multifunctional alcohols. It is actively involved in the oxidation of N-protected-amino alcohols without epimerization and allylic alcohols.

Uses

Oxidizing reagent.

reaction suitability

reagent type: oxidant

Synthesis

2-Iodobenzoic acid (50.0 g,0.20 mol) was added to cyclobutanesulfone (250 mL), and the solution was heated to 50 ??C. 90% of the above solution was slowly added dropwise to an aqueous solution of potassium persulfate (147.4g,0.24mol,1.2eq) at 50??C (300mL) and the reaction was held for 3 hours. Subsequently, the reaction solution was heated to 95 ??C and the remaining 10% 2-iodobenzoic acid solution was slowly added dropwise to the reaction solution and the reaction was continued for 3 hours. Upon completion of the reaction, the reaction was cooled to 5 ??C and stirring was continued at this temperature for 1.5 hours. Under stirring, 1 L of water was added, filtered (the filtrate was to be recycled for set use), the filter cake was washed with water and acetone sequentially, and dried at room temperature for 16 hours to obtain 53.2 g of 2-iodobenzoic acid (yield 95.04%), white solid, with a purity of 99.7% (confirmed by NMR and HPLC). The solid was identified as 2-iodoacylbenzoic acid by HNMR.

2-Iodoacylbenzoic acid (45 g, 0.16 mol) was added to acetic anhydride (49 g, 0.48 mol) and dioxane (90 mL), followed by B(C6F5)3 (0.0016 mol) followed by B(C6F5)3 (0.0016 mol), and the reaction solution was heated to 50 ??C and stirred for 10 min, then the solvent was evaporated off by spin-drying under reduced pressure, and the reaction solution was added to methyl tert-butyl ether (400 mL). Filtered and dried at room temperature to obtain a white solid (61.1 g, yield: 90%). The purity of Desmartin oxidizer was 99.1% (confirmed by NMR).

Advantages

Benefits of using Dess-Martin periodinane (DMP) as an oxidizing reagent:
milder reaction conditions (room temperature, neutral pH)
shorter reaction times and higher yields
high chemoselectivity
tolerance of sensitive functional groups, and a long shelf life
simplified workups

Dess-Martin periodinane Preparation Products And Raw materials

Raw materials

2-Iodobenzoic acid p-Toluenesulfonic acid Acetic anhydride 2-Iodoxybenzoic acid Potassium bromate Acetic acid

Preparation Products

C-(3,4-DIHYDRO-2H-BENZO[1,4]OXAZIN-3-YL)-METHYLAMINE

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Dess-Martin periodinane Suppliers

Americas 1 Belgium 4 Canada 4 CHINA 418 Czech Republic 1 Europe 3 France 2 Germany 7 India 64 Japan 6 Poland 1 Spain 2 Switzerland 3 The Netherlands 2 United Kingdom 24 United States 59 Global 601

Herd chemical

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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Jiaxing Deyi Chemical Co., Ltd

Tel: 05738586660
Email: jiaxingshidy@163.com
Country: China
ProdList: 7855
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19906
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Sigma-Aldrich

Tel: 021-61415566 800-8193336
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Nanjing Yihua Biotechnology Co., Ltd

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Shanghai ChemIDo Co., Ltd.

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Shanghai Boyle Chemical Co., Ltd.

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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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3B Pharmachem (Wuhan) International Co.,Ltd.

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View Lastest Price from Dess-Martin periodinane manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Dess-Martin periodinane 87413-09-0
Price: US $79.00-38.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-11-21

R&D Scientific Inc.

Product: 1,1,1-triacetoxy-1,1-dihydro-1,2-benziodoxol-3(1H)-one 87413-09-0
Price: US $786.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-11-12

ANHUI WITOP BIOTECH CO., LTD

Product: Dess-Martin periodinane 87413-09-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10 tons
Release date: 2021-03-23

87413-09-0, Dess-Martin periodinaneRelated Search:

ACETYLTHIOCHOLINE IODIDE 4-Acetoxystyrene Dihydromyrcenol ACETYLCHOLINE IODIDE Benzyloxyacetyl chloride Sodium triacetoxyborohydride (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one Entecavir 6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine Methyl (R)-2-(Benzylamino)-3-hydroxypropanoate N-Benzyl-DL-serine Methyl Ester HATU Dichloromethane 2-Iodobenzoic acid (Diacetoxyiodo)benzene Dess-Martin periodinane

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dess-martin periodinate

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Martin's reagent

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Dess-Martin periodinane, 15 wt.% solution in dichloromethane, AcroSeal

1,1-dihydro-1,1,1-triacetoxy-1,2-benziodoxol-3(1H)-one

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Deiss Martin reagent

DESS-MARTIN

DESS-MARTIN PERIODINANE

DESS-MARTIN REAGENT

DESSS-MARTIN PERIODINANE

1,1-DIHYDRO-1,1,1-TRIACETOXY-1,2-BENZOIODOOXOL-3(1H)-ONE

1,1,1-TRIACETOXY-1,1-DIHYDRO-1,2-BENZIODOXOL-3(1H)-ONE

1,1,1-TRIS(ACETYLOXY)-1,1-DIHYDRO-1,2-BENZIODOXOL-3-(1H)-ONE

ACETIC ACID 1,1-DIACETOXY-3-OXO-1L5-IODA-2-OXA-INDAN-1-YL ESTER

TRIACETOXYPERIODINANE

Dess-Martinperiodinane,97%

Dess-Martin periodane

3-oxo-1l5-benzo[d][1,2]iodaoxole-1,1,1(3H)-triyl triacetate

1,1,1-TRIACETOXY-1,1-DIHYDRO-1,2-BENZIODOXOL-3(1H)-ONE(DESSMARTINE)

1,1-DIHYDRO-1,1,1-TRIACETOXY-1,2-BENZOIODOOXOL-3(1H)-ONE (DESS-MARTIN PERIODINANE)

DESS-MARTIN(1,1,1-TRIACETOXY-1,1-DIHYDRO-1,2-BENZIODOXOL-3(1H)-ONE)

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Dess-Martin Periodinane (8-12% in Dichloromethane)

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RARECHEM AR PA 0035

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DESS-MARTINE

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Dess-martin oxidizer

PERIODINANE

1,1-bis(acetyloxy)-3-oxo-3H-1λ,2-benziodaoxol-1-yl acetate

Dess-Martin Periodinane (DMP)

Aceticacid,1,1',1''-(3-oxo-1λ5-1,2-benziodoxol-1(3H)-ylidyne)ester

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Days Martin oxidant

Dess-MartinPeriodinane&gt