3-(Trifluoromethyl)benzaldehyde

ChemicalBook > CAS DataBase List > 3-(Trifluoromethyl)benzaldehyde

3-(Trifluoromethyl)benzaldehyde

Uses

Product Name: 3-(Trifluoromethyl)benzaldehyde
CAS No.: 454-89-7
Chemical Name: 3-(Trifluoromethyl)benzaldehyde
Synonyms: MTF-BAD;3-(three fluoroMethyl;Cinacalcet Impurity 56;3-TRIFLUORMETHYLBENZALDEHYDE;m-Trifuoromethylbenzaldehyde;M-TRIFLUOROMETHYLBENZALDEHYDE;3-TRIFLUOROMETHYLBENZYLDEHYDE;Alpha-Trifluoro-M-tolualdehyde;A,A,A-TRIFLUORO-3-TOLUALDEHYDE;A,A,A-TRIFLUORO-M-TOLUALDEHYDE
CBNumber: CB2759919
Molecular Formula: C8H5F3O
Formula Weight: 174.12
MOL File: 454-89-7.mol

Less

3-(Trifluoromethyl)benzaldehyde Property

Boiling point:: 83-86 °C30 mm Hg(lit.)
Density: 1.301 g/mL at 25 °C(lit.)
refractive index: n20/D 1.465(lit.)
Flash point:: 155 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Liquid
color: Clear colorless to very slightly orange
Specific Gravity: 1.301
Sensitive: Air Sensitive
BRN: 2327537
InChIKey: NMTUHPSKJJYGML-UHFFFAOYSA-N
CAS DataBase Reference: 454-89-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzaldehyde, 3-(trifluoromethyl)-(454-89-7)
EPA Substance Registry System: Benzaldehyde, 3-(trifluoromethyl)- (454-89-7)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN3082 - class 9 - PG 3 - DOT NA1993 - Environmentally hazardous substances, liquid, n.o.s. HI: all (not BR)
WGK Germany: 3
F: 10-23
TSCA: T
HazardClass: IRRITANT
HS Code: 29130000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196878
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: 97%
Packaging: 25g
Price: $42.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 196878
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: 97%
Packaging: 5g
Price: $61.8
Updated: 2024/03/01

TCI Chemical

Product number: T1399
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: >95.0%(GC)
Packaging: 5g
Price: $34
Updated: 2024/03/01

TCI Chemical

Product number: T1399
Product name: 3-(Trifluoromethyl)benzaldehyde
Purity: >95.0%(GC)
Packaging: 25g
Price: $98
Updated: 2024/03/01

Alfa Aesar

Product number: A10463
Product name: 3-(Trifluoromethyl)benzaldehyde, 97%
Packaging: 5g
Price: $48.65
Updated: 2024/03/01

Less

3-(Trifluoromethyl)benzaldehyde Chemical Properties,Usage,Production

Uses

3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY ORANGE LIQUID

Uses

3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-╬│-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 426, 1946 DOI: 10.1021/ja01207a024

General Description

Aldol reaction of 3-(trifluoromethyl)benzaldehyde with hydroxyacetone in the aldolase antibody 38C2-ionic liquid system has been investigated.

3-(Trifluoromethyl)benzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

3-(3-Trifluoromethylphenyl)propionic acid

Less

3-(Trifluoromethyl)benzaldehyde Suppliers

Belgium 3 China 352 Europe 3 France 3 Germany 12 India 14 Italy 1 Japan 5 Jordan 1 Poland 1 Russia 1 Slovakia 1 Switzerland 4 Ukraine 1 United Kingdom 24 United States 47 Global 473

CHANGZHOU FLUORIDE CHEMICAL CO.,LTD

Tel: 15995021858
Fax: 0519-85227531
Email: info@fluoridechem.com
Country: China
ProdList: 80
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd.

Tel: 0519-85195575 15861192208
Fax: 85195585
Email: 850305@sunkechem.com
Country: China
ProdList: 77
Advantage: 69

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7639
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35906
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12458
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11605
Advantage: 64

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9816
Advantage: 59

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 21-31038972 15721252604
Fax: +86-21-51385350
Email: ammyzuo@harvest-chem.com
Country: China
ProdList: 2511
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17987
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8613162137806 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
Country: China
ProdList: 9747
Advantage: 57

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4388
Advantage: 65

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11714
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 21-21-56491756 13512199871
Fax: 021-5649-1756
Email: sales@panhongchem.com
Country: China
ProdList: 4001
Advantage: 55

Tianjin Jinyuda Chemical Co., Ltd.

Tel: 022-58013646 13011382049
Fax: 022-23854368
Email: sales@jinyudachem.com
Country: China
ProdList: 1882
Advantage: 55

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9725
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9872
Advantage: 52

Wuhan TCASChem Technology Co., Ltd.

Tel: 027-86697669 13986148687
Fax: 86-027-86697669
Email: sales@tcaschem.com
Country: China
ProdList: 4078
Advantage: 55

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17779
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6139
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19918
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18216
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9552
Advantage: 55

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4576
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9906
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7876
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8033
Advantage: 55

BeiJing Greenchem Technology Co.,Ltd.

Tel: 13842764302; 13842764302
Fax: 010-62925455
Email: chemrocking@bjgreenchem.com
Country: China
ProdList: 461
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Shanghai Huikai Chemical Technology Co., Ltd.

Tel: 021-61995394 18916691159
Email: chemicalsea@163.com
Country: China
ProdList: 1975
Advantage: 58

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3933
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9908
Advantage: 55

Conier Chem & Pharma Co.,Ltd,

Tel: 023-62879767 13996269627;
Fax: +86-28-84559521
Email: sales@conier.com
Country: China
ProdList: 295
Advantage: 56

Less

View Lastest Price from 3-(Trifluoromethyl)benzaldehyde manufacturers

Hebei Duling International Trade Co. LTD

Product: 3-(Trifluoromethyl)benzaldehyde 454-89-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 Ton
Release date: 2022-11-14

Hebei Kingfiner Technology Development Co.Ltd

Product: 3-(Trifluoromethyl)benzaldehyde 454-89-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000kg
Release date: 2023-10-31

Hebei Fengqiang Trading Co., LTD

Product: 3-(Trifluoromethyl)Benzaldehyde 454-89-7
Price: US $100.00/drum
Min. Order: 1drum
Purity: 99
Supply Ability: 5000
Release date: 2023-09-07

454-89-7, 3-(Trifluoromethyl)benzaldehydeRelated Search:

2-Methylbenzotrifluoride Benzaldehyde 3-Aminobenzotrifluoride 2-(Trifluoromethyl)benzoic acid (Trifluoromethyl)trimethylsilane 3-(Trifluoromethyl)anisole 3-(Trifluoromethyl)benzoyl chloride 3-Trifluoromethylphenol 3-(Trifluoromethyl)phenylacetone 3-(Trifluoromethyl)benzoic acid Trifluoromethanesulfonic acid p-Tolualdehyde 4-(Trifluoromethoxy)benzaldehyde 4-(Trifluoromethyl)benzoic acid alpha,alpha,alpha-Trifluoro-o-toluoyl chloride 4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID 1-NAPHTHALEN-2-YL-ETHYLAMINE 3-(3-METHYLPHENYL)PROPIONIC ACID

m-Trifluoromethoxy benzaldehyde

3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-3-tolualdehyde

Alpha-Trifluoro-M-tolualdehyde

3-(TrifluoroMethyl)benzaldehyde, 97% 25GR

3-(TrifluoroMethyl)benzaldehyde, 97% 5GR

3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-m-tolualdehyde

3-(three fluoroMethyl)benzeneforMaldehyde

Between the three groups in benzene forMaldehyde

alpha,alpha,alpha-Trifluoro-m-toluylaldehyde

3-TRIFLUORMETHYLBENZALDEHYDE

3-(TRIFLUOROMETHYL)BENZALDEHYDE

A,A,A-TRIFLUORO-3-TOLUALDEHYDE

A,A,A-TRIFLUORO-M-TOLUALDEHYDE

alpha,alpha,alpha-Trifluoro-3-tolualdehyde

ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUALDEHYDE

Cinacalcet Impurity 56

BENZOTRIFLUORIDE-3-CARBALDEHYDE

MTF-BAD

M-TRIFLUOROMETHYLBENZALDEHYDE

3-(trifluoromethyl)-benzaldehyd

m-Tolualdehyde, alpha,alpha,alpha-trifluoro-

m-Trifluoromethylbenzaldehyde 3-Trifluoromethyl Benzaldehyde

3-TRIFLUOROMETHYLBENZYLDEHYDE

m-Trifluoromethylbenzaldehyde,97%

à,à,à-trifluoro-m-tolualdehyde

3-(Trifluoromethyl)benzaldehyde98%

A,A,A-TRIFLUORO-META-TOLUALDEHYDE

ALPHA,ALPHA,ALPHA-TRIFLUORO-META-TOLUALDEHYDE

α,α,α-Trifluoro-m-toluylaldehyde

m-Trifuoromethylbenzaldehyde

Benzaldehyde, 3-(trifluoromethyl)-

3-(Trifluoromethyl)benzaldehyde,97%

3-(three fluoroMethyl

3-(Trifluorzomethyl)Benzaldehyde

trifluoromethylbenzaldehyde-13C6

454-89-7

455-89-7

454-89-1

454-89-71

455-89-7

C8H5F3O

ALDEHYDE

Organic Building Blocks

Aldehydes

Building Blocks

Carbonyl Compounds

Benzotrifluoride Series

Aromatic Aldehydes & Derivatives (substituted)

Benzaldehyde

3-(Trifluoromethyl)benzaldehyde

bc0001