ETHAMIVAN

Product Name: ETHAMIVAN
CAS No.: 304-84-7
Chemical Name: ETHAMIVAN
Synonyms: Emivan;Vandid;Romecor;Sevanil;Sevinal;Simaron;Etamivan;ETHAMIVAN;Corivanil;Ventilone
CBNumber: CB0407636
Molecular Formula: C12H17NO3
Formula Weight: 223.27
MOL File: 304-84-7.mol

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ETHAMIVAN Property

Melting point:: 96-97 °C
Boiling point:: 364.56°C (rough estimate)
Density: 1.1223 (rough estimate)
refractive index: 1.5300 (estimate)
storage temp.: Store at -20°C
solubility: methanol: 0.1 g/mL, clear
pka: 8.73±0.20(Predicted)
form: A solid
Merck: 13,3756
CAS DataBase Reference: 304-84-7

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 36/37/39-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: YW5250000
HazardClass: 6.1(b)
PackingGroup: III
Toxicity: LD50 i.p. in rats: 28 mg/kg (Caujolle)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S360554
Product name: N,N-DIETHYLVANILLAMIDE
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2024/03/01

Cayman Chemical

Product number: 30876
Product name: Ethamivan
Packaging: 250mg
Price: $45
Updated: 2024/03/01

Cayman Chemical

Product number: 30876
Product name: Ethamivan
Packaging: 500mg
Price: $85
Updated: 2024/03/01

Cayman Chemical

Product number: 30876
Product name: Ethamivan
Packaging: 1g
Price: $160
Updated: 2024/03/01

TRC

Product number: V973580
Product name: Vanillicaciddiethylamide
Packaging: 25mg
Price: $105
Updated: 2021/12/16

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ETHAMIVAN Chemical Properties,Usage,Production

Originator

Emivan,U.S.V.,US,1961

Uses

antihypertensive, vasoconstrictor

Uses

Vanillic acid diethylamide is a central nervous system and respiratory stimulant.

Definition

ChEBI: Etamivan is phenol substituted at C-2 and C-4 by a methoxy group and an N,N-diethylaminocarbonyl group respectively. A respiratory stimulant drug related to nikethamide, it has now fallen largely into disuse. It is a member of phenols and a member of methoxybenzenes.

Manufacturing Process

4 g of vanillinic acid are mixed with 3.6 g of diethylamine, after cooling 2.2 g of phosphorus pentoxide and the same amount of glass powder are added, and then reacted with xylene until a thin paste has been formed. The latter is boiled for some hours in the reflux cooler, moisture being excluded. Decantation follows, and the residue is dissolved by means of a warm solution of potassium carbonate until only glass powder or small amount of impurities remain undissolved, and then the xylene solution is shaken up therewith, The xylene solution is then separated, the aqueous layer is again extracted with ether, and the ether extract is combined with the xylene solution. The mixture is then distilled under the lowest possible pressure, collecting the fraction between 170°C and 250°C (referred to 10 Torr), and purifying it by further fractionation. In this way a slightly yellowish oil is obtained, which crystallizes after some time. By dissolving in ligroin and crystallizing, pure vanillinic acid diethylamide is obtained in the form of white needles; MP 95°C to 95.5°C.

brand name

Vandid (3M Pharmaceuticals).

Therapeutic Function

Central and respiratory stimulant

World Health Organization (WHO)

Etamivan is a central and respiratory stimulant.

ETHAMIVAN Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHAMIVAN Suppliers

China 19 India 2 Switzerland 1 United Kingdom 1 United States 6 Global 29

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: +86 (21) 5895-8628
Email: SALES@UHNSHANGHAI.COM
Country: China
ProdList: 977
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7892
Advantage: 56

Shenzhen Newcore Chemical Technology Co., Ltd.

Tel: 13612807752
Email: ncchemical@163.com
Country: China
ProdList: 290
Advantage: 55

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9293
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49390
Advantage: 58

Beijing Haite lesk Technology Co., Ltd

Tel: 15210893940; 15116916250
Fax: QQ: 237008221
Email: chemistryliu@163.com
Country: China
ProdList: 7327
Advantage: 58

304-84-7, ETHAMIVANRelated Search:

Vanillic acid ETHAMIVAN VESNARINONE trimetozine 1-BCP 3-ethoxy-N,N-diethyl-4-hydroxybenzamide Moxilubant Trocimine PYRROLIDINE, 1-(1,3-BENZODIOXOL-5-YLCARBONYL)- [6,7-DIMETHOXY-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL](3,4,5-TRIMETHOXYPHENYL)METHANONE Carbamic acid, (3-methylbutyl)-, (1,4-bis(3,4,5-trimethoxybenzoyl)-2-p iperazinyl)methyl ester TOSLAB 12738 1,4-Bis(3,4,5-trimethoxybenzoyl)-N-(2-chlorophenyl)-2-piperazinecarbox amide 1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinemethanol acetate (ester) Carbamic acid, (2-methylbutyl)-, (1,4-bis(3,4,5-trimethoxybenzoyl)-2-p iperazinyl)methyl ester AURORA 22851 AKOS 214-30 Hexyl 1,4-bis(3,4,5-trimethoxybenzoyl)-2-piperazinecarboxylate

N,N-DIETHYL-4-HYDROXY-3-METHOXYBENZAMIDE

N,N-DIETHYLVANILLAMIDE

VANILLIC ACID DIETHYLAMIDE

ETHAMIVAN

LABOTEST-BB LT00244804

3-Methoxy-4-hydroxybenzoic acid diethylamide

3-Methoxy-4-hydroxybenzoic acid diethylamidene

3-methoxy-4-hydroxybenzoicaciddiethylamide

N-Diethylvanillamide

Ethamivan, N,N-Diethyl-4-hydroxy-3-methoxybenzamide, N,N-Diethylvanillamide

Analepticon

Benzamide, N,N-diethyl-4-hydroxy-3-methoxy-

Cardiovamil

Cardiovanil

Corivanil

Diethamivan

Diethylamide de vanillique

diethylamidedevanillique

Diethylvanillamide

Emivan

Etamivan

Etamivanum

n,n-diethyl-4-hydroxy-3-methoxy-benzamid

n,n-diethyl-vanillamid

NSC-406087

Romecor

Sevanil

Sevinal

Simaron

Vandid

Vanillic acid N,N-diethylamide

vanillicacidn,n-diethylamide

Vanillinsaeure-diaethylamid

Ventilone

ETHAMIVAN USP/EP/BP

Inhibitor,Etamivan,inhibit

304-84-7

CNS and respiratory stimulant.

Carbonyl Compounds

Building Blocks

Amides

Organic Building Blocks

ORVATEN