trimetozine

Product Name: trimetozine
CAS No.: 635-41-6
Chemical Name: trimetozine
Synonyms: V 7;Opalene;PS-2383;PS 2383;NSC-62939;Trioxazin;Sedoxazine;TriMetozin;Trioxazine;Abbott-22370
CBNumber: CB5875528
Molecular Formula: C14H19NO5
Formula Weight: 281.3
MOL File: 635-41-6.mol

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trimetozine Property

Melting point:: 120-122°
Boiling point:: 423.97°C (rough estimate)
Density: 1.1755 (rough estimate)
refractive index: 1.5230 (estimate)
pka: -1.60±0.20(Predicted)
form: Solid
color: White to off-white

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Safety

Toxicity: LD50 oral in rat: 1800mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S570621
Product name: 4-(3,4,5-TRIMETHOXYBENZOYL)-MORPHOLINE
Purity: AldrichCPR
Packaging: 250MG
Price: $179
Updated: 2024/03/01

TRC

Product number: T798200
Product name: Trimetozine
Packaging: 5g
Price: $1055
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 62447
Product name: Trimetozine
Packaging: 5G
Price: $1460
Updated: 2021/12/16

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trimetozine Chemical Properties,Usage,Production

Originator

Opalene,Theraplix,France,1966

Uses

antiurolithic, depigmentation, radiation protectant

Uses

A sedative with mild tranquilizing effects. It has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine.

Uses

A sedative with mild tranquilizing effects. Trimetozine has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine.

Definition

ChEBI: 4-morpholinyl-(3,4,5-trimethoxyphenyl)methanone is a member of morpholines.

Manufacturing Process

46 g 3,4,5-trimethoxybenzoyl chloride are dissolved in 300 ml anhydrous benzene and 25 g triethylamine and thereafter 19 g anhydrous morpholine are added in small portions with ice-cooling. The solution is boiled for 2 hours under reflux. The precipitate is filtered off, and the solution is washed with dilute sulfuric acid, then with sodium hydrogen carbonate solution and finally with water, and then evaporated. The residual yellow oil soon crystallizes; the crystalline mass of the desired material is taken up with ether, filtered and then recrystallized from 90% ethanol, from which it separates in prisms. It is slightly soluble in water. Yield: 80%. melting point 120°C to 122°C.

Therapeutic Function

Sedative

trimetozine Preparation Products And Raw materials

Raw materials

Preparation Products

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trimetozine Suppliers

Canada 1 China 26 Germany 1 India 1 United States 5 Global 34

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4553
Advantage: 55

Henan Alfachem Co.,Ltd.

Tel: 0371-0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9868
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 56902
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32063
Advantage: 58

635-41-6, trimetozineRelated Search:

3,5-DIMETHOXY-4-HYDROXYBENZAMIDE (3,5-DIMETHOXYBENZYL)METHYLAMINE N-Formylmorpholine 3,5-Dimethoxybenzylamine ETHAMIVAN N-METHYL-3,4,5-TRIMETHOXYBENZYLAMINE 3-METHOXY-N,N-DIMETHYLBENZYLAMINE 3,4,5-TRIMETHOXYBENZAMIDE 3,4-DIHYDROXYBENZAMIDE N,N-DIETHYLBENZAMIDE N-Acetylmorpholine N-Benzyl-N-methylethanolamine 3,5-Dimethoxybenzaldehyde DIMETHYLAMINOMETHYLPHENOL 3,4,5-Trimethoxybenzaldehyde 4-Methoxybenzamide 3,4,5-TRIHYDROXYBENZAMIDE Veratrylamine

Abbott-22370

NSC-62939

PS 2383

PS-2383

morpholin-4-yl-(3,4,5-trimethoxyphenyl)methanone

morpholino-(3,4,5-trimethoxyphenyl)methanone

4-(3,4,5-TriMethoxybenzoyl)tetrahydro-1,4-oxazine

4-Morpholinyl(3,4,5-triMethoxyphenyl)Methanone

N-(3,4,5-TriMethoxybenzoyl)tetrahydro-1,4-oxazine

Opalene

Sedoxazine

Trifenoxazine

TriMetozin

Trioxazin

Trioxazine

V 7

Methanone, 4-Morpholinyl(3,4,5-triMethoxyphenyl)-

trimetozine USP/EP/BP

635-41-6

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Metabolites & Impurities

Neurochemicals

Pharmaceuticals