trimetozine

Product Name: trimetozine
CAS No.: 635-41-6
Chemical Name: trimetozine
Synonyms: V 7;Opalene;PS-2383;PS 2383;NSC-62939;Trioxazin;Sedoxazine;TriMetozin;Trioxazine;Abbott-22370
CBNumber: CB5875528
Molecular Formula: C14H19NO5
Formula Weight: 281.3
MOL File: 635-41-6.mol

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trimetozine Property

Melting point:: 120-122°
Boiling point:: 423.97°C (rough estimate)
Density: 1.1755 (rough estimate)
refractive index: 1.5230 (estimate)
pka: -1.60±0.20(Predicted)
form: Solid
color: White to off-white

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Safety

Toxicity: LD50 oral in rat: 1800mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S570621
Product name: 4-(3,4,5-TRIMETHOXYBENZOYL)-MORPHOLINE
Purity: AldrichCPR
Packaging: 250MG
Price: $179
Updated: 2024/03/01

TRC

Product number: T798200
Product name: Trimetozine
Packaging: 5g
Price: $1055
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 62447
Product name: Trimetozine
Packaging: 5G
Price: $1460
Updated: 2021/12/16

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trimetozine Chemical Properties,Usage,Production

Originator

Opalene,Theraplix,France,1966

Uses

antiurolithic, depigmentation, radiation protectant

Uses

A sedative with mild tranquilizing effects. It has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine.

Uses

A sedative with mild tranquilizing effects. Trimetozine has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine.

Definition

ChEBI: 4-morpholinyl-(3,4,5-trimethoxyphenyl)methanone is a member of morpholines.

Manufacturing Process

46 g 3,4,5-trimethoxybenzoyl chloride are dissolved in 300 ml anhydrous benzene and 25 g triethylamine and thereafter 19 g anhydrous morpholine are added in small portions with ice-cooling. The solution is boiled for 2 hours under reflux. The precipitate is filtered off, and the solution is washed with dilute sulfuric acid, then with sodium hydrogen carbonate solution and finally with water, and then evaporated. The residual yellow oil soon crystallizes; the crystalline mass of the desired material is taken up with ether, filtered and then recrystallized from 90% ethanol, from which it separates in prisms. It is slightly soluble in water. Yield: 80%. melting point 120°C to 122°C.

Therapeutic Function

Sedative

trimetozine Preparation Products And Raw materials

Raw materials

Preparation Products

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trimetozine Suppliers

Canada 1 China 28 Germany 1 India 1 United States 5 Global 36

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635-41-6, trimetozineRelated Search:

3,5-DIMETHOXY-4-HYDROXYBENZAMIDE (3,5-DIMETHOXYBENZYL)METHYLAMINE N-Formylmorpholine 3,5-Dimethoxybenzylamine ETHAMIVAN N-METHYL-3,4,5-TRIMETHOXYBENZYLAMINE 3-METHOXY-N,N-DIMETHYLBENZYLAMINE 3,4,5-TRIMETHOXYBENZAMIDE 3,4-DIHYDROXYBENZAMIDE N,N-DIETHYLBENZAMIDE N-Acetylmorpholine N-Benzyl-N-methylethanolamine 3,5-Dimethoxybenzaldehyde DIMETHYLAMINOMETHYLPHENOL 3,4,5-Trimethoxybenzaldehyde 4-Methoxybenzamide 3,4,5-TRIHYDROXYBENZAMIDE Veratrylamine

Abbott-22370

NSC-62939

PS 2383

PS-2383

morpholin-4-yl-(3,4,5-trimethoxyphenyl)methanone

morpholino-(3,4,5-trimethoxyphenyl)methanone

4-(3,4,5-TriMethoxybenzoyl)tetrahydro-1,4-oxazine

4-Morpholinyl(3,4,5-triMethoxyphenyl)Methanone

N-(3,4,5-TriMethoxybenzoyl)tetrahydro-1,4-oxazine

Opalene

Sedoxazine

Trifenoxazine

TriMetozin

Trioxazin

Trioxazine

V 7

Methanone, 4-Morpholinyl(3,4,5-triMethoxyphenyl)-

trimetozine USP/EP/BP

Trimetozine, 10 mM in DMSO

635-41-6

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Metabolites & Impurities

Neurochemicals

Pharmaceuticals