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6-METHYLBENZOTHIOPYRAN-4(4H)-ONE

Product Name
6-METHYLBENZOTHIOPYRAN-4(4H)-ONE
CAS No.
6948-34-1
Chemical Name
6-METHYLBENZOTHIOPYRAN-4(4H)-ONE
Synonyms
Einecs 230-114-8;6-METHYLTHIOCHROMANONE;6-METHYLTHIOCHROMAN-4-ONE;6-methyl-4H-thiochromen-4-one;6-METHYLBENZOTHIOPRAN-4(4H)-ONE;6-METHYLBENZOTHIOPYRAN-4(4H)-ONE;6-methyl-2,3-dihydrothiochromen-4-one;6-Methylthiochroman-4-one in isooctane;3,4-Dihydro-6-methyl-2H-1-benzothiopyran-4-one;2,3-dihydro-6-methyl-4H-1-benzothiopyran-4-one
CBNumber
CB0408138
Molecular Formula
C10H10OS
Formula Weight
178.25
MOL File
6948-34-1.mol
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6-METHYLBENZOTHIOPYRAN-4(4H)-ONE Property

Melting point:
41-45 °C(lit.)
Boiling point:
174 °C(Press: 10 Torr)
Density 
1.200±0.06 g/cm3(Predicted)
Flash point:
110 °C
storage temp. 
Sealed in dry,Room Temperature
Appearance
Light yellow to orange Solid
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
J98948
Product name
6-Methylthiochroman-4-one
Packaging
100mg
Price
$22
Updated
2021/12/16
Apolloscientific
Product number
OR33257
Product name
6-Methyl-3,4-dihydro-2H-1-benzothiopyran-4-one
Purity
95%
Packaging
1g
Price
$856
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0114975
Product name
6-METHYLTHIOCHROMAN-4-ONE
Purity
95.00%
Packaging
100MG
Price
$584.55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0114975
Product name
6-METHYLTHIOCHROMAN-4-ONE
Purity
95.00%
Packaging
250MG
Price
$623.35
Updated
2021/12/16
Alichem
Product number
6948341
Product name
6-Methylthiochroman-4-one
Packaging
10g
Price
$786.79
Updated
2021/12/16
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6-METHYLBENZOTHIOPYRAN-4(4H)-ONE Chemical Properties,Usage,Production

Synthesis

13739-35-0

6948-34-1

General procedure for the synthesis of 6-methylthiobenzodihydropyran-4-one from 3-[(4-methylphenyl)thio]propionic acid: 20 g (0.1 mol) of 3-[(4-methylphenyl)thio]propionic acid was dissolved in a 1000 ml beaker containing 70 ml of concentrated sulphuric acid, and the reaction was carried out for 12 h at room temperature. Upon completion of the reaction, the reaction mixture was cooled in an ice-water bath to precipitate a large amount of yellow solid precipitate, which was subsequently filtered. The filter cake was washed sequentially with 5% sodium bicarbonate solution and distilled water until neutral. The crude product was purified by recrystallization from 50% ethanol solution to give 16.88 g of light yellow solid 6-methylthiobenzodihydropyran-4-one in 93% yield.

References

[1] Letters in Organic Chemistry, 2016, vol. 13, # 3, p. 206 - 216
[2] Journal of Chemical Research, 2004, # 6, p. 394 - 395
[3] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 13, p. 4569 - 4574
[4] Chinese Journal of Chemistry, 2011, vol. 29, # 4, p. 757 - 764
[5] Chemische Berichte, 1923, vol. 56, p. 1275

6-METHYLBENZOTHIOPYRAN-4(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-METHYLBENZOTHIOPYRAN-4(4H)-ONE Suppliers

Synthonix Inc
Tel
--
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info@synthonix.com
Country
United States
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6872
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Matrix Scientific
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sales@matrixscientific.com
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United States
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6632
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Frontier Scientific Services, Inc.
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customerservice@frontierssi.com
Country
United States
ProdList
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Amfinecom Inc.
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Sunshine Chemlab, Inc.
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Reagent World
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ASDI Incorporated
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Riedel-de Haen AG
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INDOFINE Chemical Company, Inc.
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3B Scientific Corporation
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Milestone PharmTech LLC
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6948-34-1, 6-METHYLBENZOTHIOPYRAN-4(4H)-ONERelated Search:


  • 6-METHYLBENZOTHIOPRAN-4(4H)-ONE
  • 6-METHYLBENZOTHIOPYRAN-4(4H)-ONE
  • 6-METHYLTHIOCHROMAN-4-ONE
  • 6-METHYLTHIOCHROMANONE
  • 2,3-dihydro-6-methyl-4H-1-benzothiopyran-4-one
  • 3,4-Dihydro-6-methyl-2H-1-benzothiopyran-4-one
  • Einecs 230-114-8
  • 6-methyl-4H-thiochromen-4-one
  • 6-methyl-2,3-dihydrothiochromen-4-one
  • 4H-1-Benzothiopyran-4-one, 2,3-dihydro-6-methyl-
  • 6-Methylthiochroman-4-one in isooctane
  • 6948-34-1
  • C10H10OS
  • Building Blocks
  • Heterocyclic Building Blocks
  • Others
  • S-Containing