ChemicalBook > CAS DataBase List > 8-BROMO-1,6-NAPHTHYRIDINE

8-BROMO-1,6-NAPHTHYRIDINE

Product Name
8-BROMO-1,6-NAPHTHYRIDINE
CAS No.
17965-74-1
Chemical Name
8-BROMO-1,6-NAPHTHYRIDINE
Synonyms
8-Bromo-1,6phthyridine;8-BROMO-1,6-NAPHTHYRIDINE;1,6-Naphthyridine, 8-bromo-
CBNumber
CB0418722
Molecular Formula
C8H5BrN2
Formula Weight
209.04
MOL File
17965-74-1.mol
More
Less

8-BROMO-1,6-NAPHTHYRIDINE Property

Boiling point:
312.0±22.0 °C(Predicted)
Density 
1.656±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
1.45±0.30(Predicted)
Appearance
Off-white to light yellow Solid
CAS DataBase Reference
17965-74-1
More
Less

Safety

HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B678674
Product name
8-Bromo-1,6-naphthyridine
Packaging
100mg
Price
$175
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB13204
Product name
8-Bromo-[1,6]naphthyridine
Packaging
100mg
Price
$180
Updated
2021/12/16
Matrix Scientific
Product number
084150
Product name
8-Bromo-1,6-naphthyridine
Purity
97%
Packaging
1g
Price
$727
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0013817
Product name
8-BROMO-1,6-NAPHTHYRIDINE
Purity
95.00%
Packaging
1G
Price
$978.69
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB13204
Product name
8-Bromo-[1,6]naphthyridine
Packaging
25mg
Price
$65
Updated
2021/12/16
More
Less

8-BROMO-1,6-NAPHTHYRIDINE Chemical Properties,Usage,Production

Synthesis

253-72-5

17965-74-1

1. Carbon tetrachloride (35 mL) solution of bromine (2.25 mL, 43.7 mmol) was added dropwise to carbon tetrachloride (200 mL) solution of 1,6-naphthyridine (4.73 g, 36.4 mmol) under stirring conditions through a charging funnel. 2. The reaction mixture was heated to reflux for 1 hour. 3. Under reflux conditions, slowly add a dropwise solution of pyridine (2.94 mL, 36.4 mmol) in carbon tetrachloride (30 mL) to the reaction mixture and continue refluxing overnight. 4. Upon completion of the reaction, the reaction mixture was cooled and filtered. 5. Digest the solid with 1 M sodium hydroxide solution (200 mL) for 1 hour. 6. The basic aqueous phase was extracted with dichloromethane (2 x 200 mL), the organic phases were combined, dried over anhydrous sodium sulfate and concentrated. 7. The oil obtained was purified by column chromatography (eluent: 10% ethyl acetate/dichloromethane) to afford 8-bromo-1,6-naphthyridine (2.03 g, 27% yield) as yellow crystals with a melting point of 79-81°C. The solid was extracted with sodium hydroxide solution (2 x 200 mL) for 1 hour.

References

[1] Chemical & Pharmaceutical Bulletin, 1986, vol. 34, # 5, p. 2018 - 2023
[2] Patent: EP1147083, 2004, B1. Location in patent: Page 47
[3] Synthesis, 2007, # 8, p. 1185 - 1196

8-BROMO-1,6-NAPHTHYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

8-BROMO-1,6-NAPHTHYRIDINE Suppliers

Canada 1 China 59 Germany 2 India 1 The Netherlands 1 United Kingdom 4 United States 10 Global 78
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7892
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
3997
Advantage
55
Dtchem Laboratories,（Gan Su）Co.,Ltd.
Tel
18993966060
Fax
0943-8288977
Email
sales@techbiochem.com
Country
China
ProdList
806
Advantage
61
ShangHai AmK Pharmaceutical Technology Co., Ltd.
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
Advantage
55
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Shanghai Carlow Chemicals Co., Ltd.
Tel
21-33526724 18930996265
Fax
+86 21 37023730
Email
info@carlowchem.com
Country
China
ProdList
1969
Advantage
50
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10109
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
4092
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9721
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Shanghai Wenjia Biomedical Technology Co., Ltd.
Tel
15001899038 15001899038;
Email
wenjiayiyao@126.com
Country
China
ProdList
996
Advantage
58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
Country
China
ProdList
19778
Advantage
58
Nanjing Hengbei Chemicals Co., Ltd.
Tel
+86-25-58393656
Fax
+86-25-58393656
Email
sales@hengbeichem.cn
Country
China
ProdList
6854
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9989
Advantage
58
Wuhan Ruilida Biomedical Technology Co., Ltd.
Tel
18201884268
Email
magean83@163.com
Country
China
ProdList
1960
Advantage
58
LEADMEDPHARM CO.,LTD
Tel
13674959855 13674959855
Email
sales@synthontech.com
Country
China
ProdList
3035
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Birdo (Shanghai) Medical Technology Co., Ltd.
Tel
021-58099077-8041 18601625411
Email
sales@birdotech.com
Country
China
ProdList
9764
Advantage
58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
Email
3525679403@qq.com
Country
China
ProdList
4989
Advantage
58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15727060112
Email
yutianchun2007@126.com
Country
China
ProdList
9814
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai Ruipu Medical Technology Co., Ltd
Tel
15895968936
Fax
qq 1018762393
Email
1018762393@qq.com
Country
China
ProdList
9999
Advantage
58
Hubei yongkuo Technology Co., Ltd
Tel
027-027-59223108 15972152991
Fax
027-59223108
Email
1248580099@qq.com
Country
China
ProdList
9944
Advantage
58
Allbio pharm Co., Ltd
Tel
1483287082 19962651230
Email
sales@allbiopharm.com
Country
China
ProdList
1529
Advantage
58
Ningbo jinuo chemical co., LTD
Tel
0574-87314919 057487319282
Email
info@nbinno.com
Country
China
ProdList
7047
Advantage
58
Shanghai Aizikang Pharmaceutical Research Co., Ltd
Tel
18721109360
Email
306685371@qq.com
Country
China
ProdList
1944
Advantage
58
JinOu Biomedical (Nanjing) Co., Ltd.
Tel
13000000000
Fax
jinoupharma@163
Email
jinoupharma@163.com
Country
China
ProdList
11721
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Shandong Mingde Biotechnology Co., Ltd
Tel
15553348166
Email
m15553348166@163.com
Country
China
ProdList
9967
Advantage
58
Shanghai Yingxin laboratory equipment Co., Ltd
Tel
021-021-59178156 15300768757
Email
359382369@qq.com
Country
China
ProdList
10674
Advantage
58
Shanghai Guchen Biotechnology Co., LTD
Tel
021-34675735 19147740836
Email
1986399151@qq.com
Country
China
ProdList
9844
Advantage
58
Shaanxi Didu New Material Co., Ltd
Tel
029-81145920 17391631969
Email
1046@dideu.com
Country
China
ProdList
9996
Advantage
58
Suzhou Haiben Pharmaceutical Co., Ltd
Tel
19353112242
Email
1816280386@qq.com
Country
China
ProdList
8045
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
sales@pharmablock.com
Country
China
ProdList
7268
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29995
Advantage
58
Shandong Mopai Biotechnology Co., Ltd
Tel
13053322091
Email
admin@mopaikeji.com
Country
China
ProdList
5830
Advantage
58
Shandong Mingde Biotechnology Co., Ltd.
Tel
18560864701
Email
643971@qq.com
Country
China
ProdList
6098
Advantage
58
Sichuan Boyou Biotechnology Co., Ltd
Tel
028-65791793 18140026355
Email
568470422@qq.com
Country
China
ProdList
9459
Advantage
58
Anhui JYHX CO., LTD.
Tel
0551-68788198 13295518198
Email
wangyanan@ahjyhx.com
Country
China
ProdList
1759
Advantage
58

17965-74-1, 8-BROMO-1,6-NAPHTHYRIDINERelated Search:

8-BROMO-[1,6]NAPHTHYRIDIN-2-OL 8-BROMO-1,6-NAPHTHYRIDINE 8-BROMO-5-CHLORO-1,6-NAPHTHYRIDINE 4-bromo-1,5-naphthyridine 2-bromo-1,5-naphthyridine 2-BROMO-1,8-NAPHTHYRIDINE 3-Bromo-1,8-naphthyridine 3-bromo-1,5-naphthyridine 2-AMINO-6-BROMO-1,8-NAPHTHYRIDINE methyl 7-bromo-1,5-naphthyridine-3-carboxylate 4-bromo-1,8-naphthyridine 2-bromo-1,7-naphthyridine 2-BROMO-1,6-NAPHTHYRIDINE 5-BROMO-[1,7]NAPHTHYRIDINE 5-BROMO-1,6-NAPHTHYRIDINE 8-BROMO-[1,6]NAPHTHYRIDINE-2-CARBOXYLIC ACID METHYLAMIDE 8-BROMO-5-CHLORO-2-(TRIFLUOROMETHYL)-1,6-NAPHTHYRIDINE 8-BROMO-1,6-NAPHTHYRIDINE-2-CARBOXYLIC ACID

  • 8-BROMO-1,6-NAPHTHYRIDINE
  • 1,6-Naphthyridine, 8-bromo-
  • 8-Bromo-1,6phthyridine
  • 17965-74-1