5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
- Product Name
- 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
- CAS No.
- 104375-88-4
- Chemical Name
- 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
- Synonyms
- DMT-5-I-dU;5'-O-DMT-5-I-2'-dU;DMT-5-I-2'-deoxyuridine;5'-DMT-5-I-2'-deoxyuridine;5'-DMT-5-iodo-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMT-5-iodo-2'-deoxyuridine;5'-O-DMT-5-iodo-2'-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMTr-5-Iodo-2'-deoxyuridine
- CBNumber
- CB0426433
- Molecular Formula
- C30H29IN2O7
- Formula Weight
- 656.46
- MOL File
- 104375-88-4.mol
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Property
- Melting point:
- >128 °C (decomp)
- Density
- 1.60±0.1 g/cm3(Predicted)
- pka
- 7.94±0.10(Predicted)
- InChIKey
- RLDUYGSOCGOJTP-SKDNVIITNA-N
- SMILES
- C(OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C(=O)NC2=O)I)O1)(C1C=CC=CC=1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,4,7,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D233065
- Product name
- 2’-Deoxy-5’-O-DMT-5-iodouridine
- Packaging
- 250mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- ND08238
- Product name
- 2'-Deoxy-5'-O-DMT-5-iodouridine
- Packaging
- 1g
- Price
- $230
- Updated
- 2021/12/16
- Product number
- ND08238
- Product name
- 2'-Deoxy-5'-O-DMT-5-iodouridine
- Packaging
- 2g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- 3467CS
- Product name
- 2'-Deoxy-5'-O-DMT-5-iodouridine
- Packaging
- 1g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- NUC0001525
- Product name
- 2'-DEOXY-5'-O-DMT-5-IODOURIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.67
- Updated
- 2021/12/16
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Chemical Properties,Usage,Production
Description
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine (2'-Deoxy-5'-O-DMT-5-iodouridine) is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.
Uses
2’-Deoxy-5’-O-DMT-5-iodouridine is a modified oligonucleotides designed for use in genetic analysis and RNA detection.
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Preparation Products And Raw materials
Raw materials
Preparation Products
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