ChemicalBook > CAS DataBase List > 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

Product Name: 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
CAS No.: 104375-88-4
Chemical Name: 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
Synonyms: DMT-5-I-dU;5'-O-DMT-5-I-2'-dU;DMT-5-I-2'-deoxyuridine;5'-DMT-5-I-2'-deoxyuridine;5'-DMT-5-iodo-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMT-5-iodo-2'-deoxyuridine;5'-O-DMTr-5-Iodo-2'-deoxyuridine;5’-O-DMTr-5-iodo-2’-deoxyuridine;5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine
CBNumber: CB0426433
Molecular Formula: C30H29IN2O7
Formula Weight: 656.46
MOL File: 104375-88-4.mol

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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Property

Melting point:: >128 °C (decomp)
Density: 1.60±0.1 g/cm3(Predicted)
pka: 7.94±0.10(Predicted)
InChIKey: RLDUYGSOCGOJTP-SKDNVIITNA-N
SMILES: C(OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C(=O)NC2=O)I)O1)(C1C=CC=CC=1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,4,7,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D233065
Product name: 2’-Deoxy-5’-O-DMT-5-iodouridine
Packaging: 250mg
Price: $165
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND08238
Product name: 2'-Deoxy-5'-O-DMT-5-iodouridine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND08238
Product name: 2'-Deoxy-5'-O-DMT-5-iodouridine
Packaging: 1g
Price: $230
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND08238
Product name: 2'-Deoxy-5'-O-DMT-5-iodouridine
Packaging: 2g
Price: $360
Updated: 2021/12/16

AK Scientific

Product number: 3467CS
Product name: 2'-Deoxy-5'-O-DMT-5-iodouridine
Packaging: 1g
Price: $360
Updated: 2021/12/16

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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Chemical Properties,Usage,Production

Description

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine (2'-Deoxy-5'-O-DMT-5-iodouridine) is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.

Uses

2’-Deoxy-5’-O-DMT-5-iodouridine is a modified oligonucleotides designed for use in genetic analysis and RNA detection.

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Suppliers

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104375-88-4, 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridineRelated Search:

Uridine Pyrazine 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine N-blocked-5'-O-DMT 3'-CED iododeoxyuridine phosphoramidite 5-IODO-2',3'-DIDEOXYURIDINE 1-(2-HYDROXY-ETHOXYMETHYL)-5-IODO-1H-PYRIMIDINE-2,4-DIONE Idoxuridine 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-O-METHYLURIDINE

5''-O-(DIMETHOXYTRITYL)-5-IODO-2''-DEOXYURIDINE 99%

5'-DMT-5-iodo-deoxyuridine

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DMT-5-I-dU

5'-O-DMTr-5-Iodo-2'-deoxyuridine

5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine

5'-O-(4,4'-Dimethoxytrityl)-5-Iodo-2'-deoxyuridine

5'-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine

5'-DMT-5-I-2'-deoxyuridine

DMT-5-I-2'-deoxyuridine

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5-Iodo-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxyuridine

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5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-DEOXYURIDINE USP/EP/BP

1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione

2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine

1-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxyoxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

5’-O-DMTr-5-iodo-2’-deoxyuridine

5-Iodo-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

5'-O-DMT-5-I-2'-dU

2′-Deoxy-5′-O-DMT-5-iodouridine, CAS 104375-88-4

104375-88-4

C30H29IN2O7