ChemicalBook > CAS DataBase List > 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

Product Name
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
CAS No.
104375-88-4
Chemical Name
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
Synonyms
DMT-5-I-dU;5'-O-DMT-5-I-2'-dU;DMT-5-I-2'-deoxyuridine;5'-DMT-5-I-2'-deoxyuridine;5'-DMT-5-iodo-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMT-5-iodo-2'-deoxyuridine;5'-O-DMTr-5-Iodo-2'-deoxyuridine;5’-O-DMTr-5-iodo-2’-deoxyuridine;5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine
CBNumber
CB0426433
Molecular Formula
C30H29IN2O7
Formula Weight
656.46
MOL File
104375-88-4.mol
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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Property

Melting point:
>128 °C (decomp)
Density 
1.60±0.1 g/cm3(Predicted)
pka
7.94±0.10(Predicted)
InChIKey
RLDUYGSOCGOJTP-SKDNVIITNA-N
SMILES
C(OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C(=O)NC2=O)I)O1)(C1C=CC=CC=1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,4,7,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D233065
Product name
2’-Deoxy-5’-O-DMT-5-iodouridine
Packaging
250mg
Price
$165
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND08238
Product name
2'-Deoxy-5'-O-DMT-5-iodouridine
Packaging
1g
Price
$230
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND08238
Product name
2'-Deoxy-5'-O-DMT-5-iodouridine
Packaging
2g
Price
$360
Updated
2021/12/16
AK Scientific
Product number
3467CS
Product name
2'-Deoxy-5'-O-DMT-5-iodouridine
Packaging
1g
Price
$360
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0001525
Product name
2'-DEOXY-5'-O-DMT-5-IODOURIDINE
Purity
95.00%
Packaging
5MG
Price
$502.67
Updated
2021/12/16
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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Chemical Properties,Usage,Production

Description

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine (2'-Deoxy-5'-O-DMT-5-iodouridine) is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.

Uses

2’-Deoxy-5’-O-DMT-5-iodouridine is a modified oligonucleotides designed for use in genetic analysis and RNA detection.

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Suppliers

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104375-88-4, 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridineRelated Search:

Uridine Pyrazine 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine N-blocked-5'-O-DMT 3'-CED iododeoxyuridine phosphoramidite 5-IODO-2',3'-DIDEOXYURIDINE 1-(2-HYDROXY-ETHOXYMETHYL)-5-IODO-1H-PYRIMIDINE-2,4-DIONE Idoxuridine 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-O-METHYLURIDINE

  • 5''-O-(DIMETHOXYTRITYL)-5-IODO-2''-DEOXYURIDINE 99%
  • 5'-DMT-5-iodo-deoxyuridine
  • 2'-Deoxy-5'-O-DMT-5-iodouridine
  • DMT-5-I-dU
  • 5'-O-DMTr-5-Iodo-2'-deoxyuridine
  • 5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine
  • 5'-O-(4,4'-Dimethoxytrityl)-5-Iodo-2'-deoxyuridine
  • 5'-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine
  • 5'-DMT-5-I-2'-deoxyuridine
  • DMT-5-I-2'-deoxyuridine
  • 5'-O-DMT-5-iodo-2'-deoxyuridine
  • 5-Iodo-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxyuridine
  • Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-iodo-
  • 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-DEOXYURIDINE USP/EP/BP
  • 1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione
  • 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine
  • 1-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxyoxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
  • 5’-O-DMTr-5-iodo-2’-deoxyuridine
  • 5-Iodo-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine
  • 5'-O-DMT-5-I-2'-dU
  • 2′-Deoxy-5′-O-DMT-5-iodouridine, CAS 104375-88-4
  • 104375-88-4
  • C30H29IN2O7