ChemicalBook > CAS DataBase List > ZOPICLONE N-OXIDE

ZOPICLONE N-OXIDE

Product Name
ZOPICLONE N-OXIDE
CAS No.
43200-96-0
Chemical Name
ZOPICLONE N-OXIDE
Synonyms
RP 2975;RP 29753;ZOPICLONE N-OXIDE;Eszopiclone IMpurity A;Zopiclone EP Impurity A;Zopiclone-N-oxide solution;Eszopiclone Related CoMpound A;Zopiclone N-Oxide Solution, 100ppm;Eszopiclone USP Related Compound A;Zopiclone Impurity A (Zopiclone N-Oxide)
CBNumber
CB0428563
Molecular Formula
C17H17ClN6O4
Formula Weight
404.81
MOL File
43200-96-0.mol
More
Less

ZOPICLONE N-OXIDE Property

Melting point:
>140°C (dec.)
Flash point:
9℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka
4.92±0.20(Predicted)
color 
White to Light Brown
More
Less

Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol
WGK Germany 
1
HS Code 
2933790002
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Z-013
Product name
Zopiclone-N-oxide solution
Purity
100?μg/mL (Methanol with 1% 1 M HCl), ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$158
Updated
2024/03/01
Sigma-Aldrich
Product number
1255861
Product name
Zopiclone-N-oxide solution
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
10mg
Price
$596
Updated
2024/03/01
Sigma-Aldrich
Product number
Z3001000
Product name
Zopiclone oxide
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
z3001000
Price
$153
Updated
2024/03/01
Usbiological
Product number
292130
Product name
Zopiclone N-oxide
Packaging
2mg
Price
$425
Updated
2021/12/16
Usbiological
Product number
Z0810-02
Product name
Zopiclone N-Oxide
Packaging
5mg
Price
$460
Updated
2021/12/16
More
Less

ZOPICLONE N-OXIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Beige Solid

Uses

A metabolite of Zopiclone

Uses

Eszopiclone impurity A.

General Description

Zopiclone N-oxide is a primary, active metabolite of zopiclone in urine as well as a major pharmaceutical impurity of zopiclone known as eszopiclone impurity A. The parent drug, zopiclone, is a non-benzodiazepine hypnotic sold under the trade names Imovane?and ZImovane?and is used in the treatment of insomnia.

ZOPICLONE N-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ZOPICLONE N-OXIDE Suppliers

Canada 2 China 53 India 4 United Kingdom 1 United States 9 Global 69
Changzhou Xianglong Pharmaceutical Technology Co., LTD
Tel
0519-88910898 18661161657
Email
yaoxiangqiu2021@163.com
Country
China
ProdList
10066
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Artis Chemistry (Shanghai) Co. Ltd.
Tel
86-21-60936353
Fax
86-21-60936352
Country
China
ProdList
336
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1958
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
Advantage
56
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7725
Advantage
55
Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2862
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9507
Advantage
60
Chengdu Novel Biomedical Co., Ltd.
Tel
028-85255396 18302801538
Fax
028-85255396
Email
cdnovell@163.com
Country
China
ProdList
2251
Advantage
58
LinkChem Co.,Ltd.
Tel
021-021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
3000
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
400-400-400-9004166 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52712
Advantage
58
Shanghai ring qi biological technology co., LTD
Tel
13524106587
Email
sales@hq-chem.com
Country
China
ProdList
225
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3063
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55896
Advantage
58
Chengdu MassCale Pharmaceutical Co., Ltd.
Tel
028-84552636 18084815636
Email
chensfsc@126.com
Country
China
ProdList
1448
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
0551-65418671
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34572
Advantage
58
sgtlifesciences pvt ltd
Tel
+8617013299288
Email
dj@sgtlifesciences.com
Country
China
ProdList
12382
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
17825480238
Fax
QQ 3008233717
Email
3008233717@qq.com
Country
China
ProdList
9843
Advantage
12
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28180
Advantage
58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.
Tel
020-89854820
Email
sales@jzpharma.cn
Country
China
ProdList
1050
Advantage
58
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14253
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49391
Advantage
58
Shenzhen Jianyi Biotechnology Co., Ltd
Tel
0755-84826604
Email
3001783715@qq.com
Country
CHINA
ProdList
2898
Advantage
58
PCL - Business, Laboratory Pharmaceutical
Tel
19150123681
Fax
QQ:3008022628
Email
Hu.xinyue@purechemland.com
Country
China
ProdList
3567
Advantage
58
Shenzhen Hengfeng Wanda Pharmaceutical Technology Co., Ltd
Tel
755-22677922-801 18126518403
Fax
518109
Email
2851922760@qq.com
Country
China
ProdList
5043
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8864
Advantage
58
Shanghai Ruipu Medical Technology Co., Ltd
Tel
15895968936
Fax
qq 1018762393
Email
1018762393@qq.com
Country
China
ProdList
9921
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44488
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12664
Advantage
58
Molcoo Chemicals Inc.
Tel
18627923403 18274848843
Email
3001006472@qq.com
Country
China
ProdList
8661
Advantage
58
Hunan Zengda Biological Technology Co., LTD
Tel
18711085600
Email
1652923704@qq.com
Country
China
ProdList
4583
Advantage
58
Shenzhen Roark Pharma-Tec Co., Ltd.
Tel
13128912434
Email
2880126944@qq.com
Country
China
ProdList
2580
Advantage
58
PureChemland Co.,Ltd.
Tel
19150123681
Email
3848291069@qq.com
Country
China
ProdList
3258
Advantage
58
Scinova Biotech(Guangzhou) Co., Ltd.
Tel
13268215580
Email
scinova_sales@163.com
Country
China
ProdList
7026
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175-877 18933936954
Email
tianwen.zhan@cato-chem.com
Country
China
ProdList
7722
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
11572
Advantage
58
Shenzhen Excellent Biomedical Technology Co., Ltd.
Tel
18318671572
Email
2850803126@qq.com
Country
China
ProdList
4993
Advantage
58
Shanghai Zerui Biotechnology Co., Ltd.
Tel
021-54580889 18321124657
Fax
021-54580889
Email
731997554@qq.com
Country
China
ProdList
10614
Advantage
58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd
Tel
18502726233
Email
3641133981@qq.com
Country
China
ProdList
9341
Advantage
58
Auonsi (Shanghai) Biology Technology Co., Ltd.
Tel
400-1107768 15058188853
Fax
0571-88150696
Email
478133536@qq.com
Country
China
ProdList
8555
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
3674309880
Email
hanfangpharma@126.com
Country
China
ProdList
30968
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
18627753421 18627756402
Fax
QQ：3001051413
Email
3001009495@qq.com
Country
China
ProdList
10441
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43348
Advantage
58
China National Standard Pharmaceutical Corporation Limited
Tel
+8615391658522
Email
overseasales@yongstandards.com
Country
China
ProdList
11927
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58
Shanghai Zhongnai Biomedical Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
79
Advantage
58

43200-96-0, ZOPICLONE N-OXIDERelated Search:

6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one Eszopiclone Levetiracetam impurity 1 N-(5-Chloro-2-pyridinyl)-2-pyrazinecarboxaMide (Zopiclone IMpurity) 2-Amino-5-chloropyridine Zopiclone RP 48497 (Eszopiclone Impurity C) N-(5-Chloro-2-pyridinyl)-3-(hydroxyMethyl)-2-pyrazinecarboxaMide ZOPICLONE OXIDE Zopiclone iMpurity (5-(Chloropyridine-2-yl-carbaMoyl)pyrazine) Zopiclone iMpurity A N-Boc-N-desmethyl Zopiclone 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI) Zopiclone Impurity 10 Zopiclone Impurity 18 Zopiclone Impurity 3 Deschloro-Zopiclone

  • RP 2975
  • 1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester
  • Zopiclone N-Oxide (Mixture of diastereomers)
  • RP 29753
  • Zopiclone N-Oxide (Eszopiclone Impurity A) (Mixture of Diastereomers)
  • Zopiclone N-Oxide (Eszopiclone Impurity A)
  • ZOPICLONE N-OXIDE
  • 4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester 4-oxide
  • Eszopiclone IMpurity A
  • Eszopiclone Related CoMpound A
  • (5RS)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate 4-oxide
  • Dexzopiclone impurity A (zopiclone nitrogen oxide)
  • Zopiclone N-Oxide Solution, 100ppm
  • Zopiclone-N-oxide solution
  • Zopiclone Impurity A (Zopiclone N-Oxide)
  • 4-(((6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl)oxy)carbonyl)-1-methylpiperazine1-oxide
  • Zopiclone Impurity 1 (Zopiclone EP Impurity A)
  • Zopiclone EP Impurity A (Zopiclone N-Oxide)
  • Zopiclone EP Impurity A
  • [6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methyl-4-oxidopiperazin-4-ium-1-carboxylate
  • 6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate 4-oxide
  • 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester, 4-oxide
  • 6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]...
  • Zopiclone N-OxideQ: What is Zopiclone N-Oxide Q: What is the CAS Number of Zopiclone N-Oxide Q: What is the storage condition of Zopiclone N-Oxide Q: What are the applications of Zopiclone N-Oxide
  • Eszopiclone Related Compound A (6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo [3,4,b] pyraz (1255861)
  • Eszopiclone USP Related Compound A
  • 43200-96-0
  • C17H17ClN6O4
  • Isotopically Labeled Pharmaceutical Reference Standard
  • Heterocycles
  • Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals