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(RS)-(TETRAZOL-5-YL)GLYCINE

Product Name
(RS)-(TETRAZOL-5-YL)GLYCINE
CAS No.
138199-51-6
Chemical Name
(RS)-(TETRAZOL-5-YL)GLYCINE
Synonyms
C13738;LY 285265;Tet-glycine;Tetrazolyl Glycine;5-Tetrazolyl-glycine;(RS)-(Tetrazol-5-yl);(tetrazol-5-yl)glycine;L-(tetrazol-5-yl)glycine;(RS)-(TETRAZOL-5-YL)GLYCINE;aMino(2H-tetrazol-5-yl)acetic acid
CBNumber
CB0429449
Molecular Formula
C3H5N5O2
Formula Weight
143.1
MOL File
138199-51-6.mol
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(RS)-(TETRAZOL-5-YL)GLYCINE Property

Boiling point:
447.1±55.0 °C(Predicted)
Density 
1.804±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
DMSO: 0.25mg/mL; PBS (pH 7.2): 0.2mg/mL
form 
Powder
pka
1.04±0.10(Predicted)
Water Solubility 
Soluble to 50 mM in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28408
Product name
Tetrazolyl Glycine
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
28408
Product name
Tetrazolyl Glycine
Packaging
100mg
Price
$693
Updated
2021/12/16
Cayman Chemical
Product number
28408
Product name
Tetrazolyl Glycine
Packaging
25mg
Price
$287
Updated
2024/03/01
Cayman Chemical
Product number
28408
Product name
Tetrazolyl Glycine
Packaging
50mg
Price
$543
Updated
2024/03/01
Tocris
Product number
0312
Product name
(RS)-(Tetrazol-5-yl)glycine
Purity
≥98%(HPLC)
Packaging
50
Price
$910
Updated
2021/12/16
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(RS)-(TETRAZOL-5-YL)GLYCINE Chemical Properties,Usage,Production

Description

Tetrazolyl glycine is an NMDA receptor agonist. It binds to rat brain membranes with IC50 values of 98 and 36 nM for [3H]CGS19755 and [3H]glutamate, respectively, in radioligand binding assays. It induces depolarization in rat cortical slices, an effect that is blocked by the NMDA receptor antagonist LY233053. It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED50 = 0.071 mg/kg). Intrastriatal injection of tetrazolyl glycine (5 μM) increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury.

Uses

(RS)-(Tetrazol-5-yl)glycine is a highly potent NMDA receptor agonist demonstrating ~ 20X more activity than NMDA.

Definition

ChEBI: Tet-glycine is a non-proteinogenic alpha-amino acid.

storage

Store at RT

(RS)-(TETRAZOL-5-YL)GLYCINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(RS)-(TETRAZOL-5-YL)GLYCINE Suppliers

China 24 Germany 1 Japan 2 South Korea 1 Ukraine 1 United Kingdom 3 United States 7 USA 1 Global 40
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
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China
ProdList
15839
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Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
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028-81705658
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3003855609@qq.com
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China
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Nantong Zandery Biotechnology Co., Ltd.
Tel
0513-87582998 13912206938
Fax
+86 (513) 87581996
Email
xiaofeizhu@vip.163.com
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China
ProdList
305
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EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
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Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
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9923
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55
Aikon International Limited
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025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15494
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Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
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jnyaoyan@163.com
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China
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Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
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United States
ProdList
32079
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Nextpeptide Inc
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sales@nextpeptide.com
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China
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138199-51-6, (RS)-(TETRAZOL-5-YL)GLYCINERelated Search:

5-aminotetrazole Lauroyl glycine SALOR-INT L159409-1EA 2-(2H-TETRAZOL-5-YL)-ETHANOL 1H-TETRAZOLE-5-ACETIC ACID C-(2H-TETRAZOL-5-YL)-METHYLAMINE (RS)-(TETRAZOL-5-YL) GLYCINE, [GLYCINE-1-14C] (RS)-(TETRAZOL-5-YL)GLYCINE CHEMBRDG-BB 4015694

  • (RS)-(TETRAZOL-5-YL)GLYCINE
  • (tetrazol-5-yl)glycine
  • 5-Tetrazolyl-glycine
  • C13738
  • Tet-glycine
  • aMino(2H-tetrazol-5-yl)acetic acid
  • Amino-(1H-tetrazol-5-yl)-acetic acid
  • 2H-Tetrazole-5-acetic acid, a-amino-
  • alpha-Amino-2H-tetrazole-5-acetic acid
  • LY 285265
  • 2H-Tetrazole-5-acetic acid, α-amino-
  • (RS)-(Tetrazol-5-yl)
  • 2-Amino-2-(2H-tetrazol-5-yl)acetic acid
  • Tetrazolyl Glycine
  • (RS)-(Tetrazol-5-yl)glycine/LY285265
  • L-(tetrazol-5-yl)glycine
  • Fos,iGluR,GluN2D,LY-285265,Ionotropic glutamate receptors,inhibit,Inhibitor,(RS)(Tetrazol5yl)glycine,GluN1,(RS) (Tetrazol 5 yl)glycine,GluN2A,LY285265,NMDA,seizure
  • 2H-Tetrazole-5-acetic acid, α-amino-
  • 138199-51-6