ChemicalBook > CAS DataBase List > (RS)-(TETRAZOL-5-YL)GLYCINE
(RS)-(TETRAZOL-5-YL)GLYCINE
- Product Name
- (RS)-(TETRAZOL-5-YL)GLYCINE
- CAS No.
- 138199-51-6
- Chemical Name
- (RS)-(TETRAZOL-5-YL)GLYCINE
- Synonyms
- C13738;LY 285265;Tet-glycine;Tetrazolyl Glycine;5-Tetrazolyl-glycine;(RS)-(Tetrazol-5-yl);(tetrazol-5-yl)glycine;L-(tetrazol-5-yl)glycine;(RS)-(TETRAZOL-5-YL)GLYCINE;aMino(2H-tetrazol-5-yl)acetic acid
- CBNumber
- CB0429449
- Molecular Formula
- C3H5N5O2
- Formula Weight
- 143.1
- MOL File
- 138199-51-6.mol
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(RS)-(TETRAZOL-5-YL)GLYCINE Property
- Boiling point:
- 447.1±55.0 °C(Predicted)
- Density
- 1.804±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- DMSO: 0.25mg/mL; PBS (pH 7.2): 0.2mg/mL
- form
- Powder
- pka
- 1.04±0.10(Predicted)
- Water Solubility
- Soluble to 50 mM in water
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28408
- Product name
- Tetrazolyl Glycine
- Packaging
- 10mg
- Price
- $121
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28408
- Product name
- Tetrazolyl Glycine
- Packaging
- 100mg
- Price
- $693
- Updated
- 2021/12/16
Cayman Chemical
- Product number
- 28408
- Product name
- Tetrazolyl Glycine
- Packaging
- 25mg
- Price
- $287
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28408
- Product name
- Tetrazolyl Glycine
- Packaging
- 50mg
- Price
- $543
- Updated
- 2024/03/01
Tocris
- Product number
- 0312
- Product name
- (RS)-(Tetrazol-5-yl)glycine
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $910
- Updated
- 2021/12/16
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(RS)-(TETRAZOL-5-YL)GLYCINE Chemical Properties,Usage,Production
Description
Tetrazolyl glycine is an NMDA receptor agonist. It binds to rat brain membranes with IC50 values of 98 and 36 nM for [3H]CGS19755 and [3H]glutamate, respectively, in radioligand binding assays. It induces depolarization in rat cortical slices, an effect that is blocked by the NMDA receptor antagonist LY233053. It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED50 = 0.071 mg/kg). Intrastriatal injection of tetrazolyl glycine (5 μM) increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury.
Uses
(RS)-(Tetrazol-5-yl)glycine is a highly potent NMDA receptor agonist demonstrating ~ 20X more activity than NMDA.
Definition
ChEBI: Tet-glycine is a non-proteinogenic alpha-amino acid.
storage
Store at RT
(RS)-(TETRAZOL-5-YL)GLYCINE Preparation Products And Raw materials
Raw materials
Preparation Products
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138199-51-6, (RS)-(TETRAZOL-5-YL)GLYCINERelated Search:
5-aminotetrazole
Lauroyl glycine
SALOR-INT L159409-1EA
2-(2H-TETRAZOL-5-YL)-ETHANOL
1H-TETRAZOLE-5-ACETIC ACID
C-(2H-TETRAZOL-5-YL)-METHYLAMINE
(RS)-(TETRAZOL-5-YL) GLYCINE, [GLYCINE-1-14C]
(RS)-(TETRAZOL-5-YL)GLYCINE
CHEMBRDG-BB 4015694