6-PHENYL-PYRIDIN-2-YLAMINE
- Product Name
- 6-PHENYL-PYRIDIN-2-YLAMINE
- CAS No.
- 39774-25-9
- Chemical Name
- 6-PHENYL-PYRIDIN-2-YLAMINE
- Synonyms
- AKOS 205-07;6-phenylpyridin-2-amine;6-Phenyl-2-pyridinaMine;2-AMINO-6-PHENYLPYRIDINE;6-AMINO-2-PHENYLPYRIDINE;2-Pyridinamine, 6-phenyl-;6-PHENYL-PYRIDIN-2-YLAMINE;Pyridine, 2-amino-6-phenyl-;6-PHENYL-PYRIDIN-2-YLAMINE ISO 9001：2015 REACH
- CBNumber
- CB0429595
- Molecular Formula
- C11H10N2
- Formula Weight
- 170.21
- MOL File
- 39774-25-9.mol
6-PHENYL-PYRIDIN-2-YLAMINE Property
- Melting point:
- 71-72℃
- Boiling point:
- 348℃
- Density
- 1.133
- Flash point:
- 191℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 5.93±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A626750
- Product name
- 2-Amino-6-phenylpyridine
- Packaging
- 100mg
- Price
- $1100
- Updated
- 2021/12/16
- Product number
- FA17665
- Product name
- 2-Amino-6-phenylpyridine
- Packaging
- 5mg
- Price
- $124.9
- Updated
- 2021/12/16
- Product number
- OR963733
- Product name
- 2-Amino-6-phenylpyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- W6009
- Product name
- 2-Amino-6-phenylpyridine
- Packaging
- 1g
- Price
- $151
- Updated
- 2021/12/16
- Product number
- 3H30-1-NJ
- Product name
- 2-Amino-6-phenylpyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
6-PHENYL-PYRIDIN-2-YLAMINE Chemical Properties,Usage,Production
Uses
A derivative of 2-aminopyridinium as potent antimalarial.
Synthesis
45644-21-1
98-80-6
39774-25-9
GENERAL STEPS: To a sealed tube was added a solution of anhydrous 1,4-dioxane (30 v/v) in 2-amino-6-chloropyridine (1.0 eq.), followed by phenylboronic acid (1.5 eq.) and finely ground potassium phosphate (2.0 eq.). The reaction mixture was degassed by nitrogen bubbling for 5 minutes, then palladium acetate (5 mol%) and di-tert-butylphosphinoferrocene (5 mol%) were added and degassing continued for 5 minutes. The reaction tube was sealed under nitrogen atmosphere and heated at 100 °C with vigorous stirring for 5 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction mixture was vacuum filtered through a diatomaceous earth pad and the precipitate was washed with 1,4-dioxane. The filtrates were combined, concentrated under reduced pressure and purified by fast column chromatography (elution gradient: pure hexane to 1:1 hexane/ethyl acetate containing 2.5 vol% triethylamine) to give 6-phenylpyridin-2-amine.
References
[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 8, p. 2742 - 2750
[2] Tetrahedron Letters, 2005, vol. 46, # 20, p. 3573 - 3577
[3] New Journal of Chemistry, 2017, vol. 41, # 24, p. 15420 - 15432
6-PHENYL-PYRIDIN-2-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
6-PHENYL-PYRIDIN-2-YLAMINE Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 6-PHENYL-PYRIDIN-2-YLAMINE manufacturers
- Product
- 6-PHENYL-PYRIDIN-2-YLAMINE 39774-25-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27