ChemicalBook > CAS DataBase List > TIMP-2, HUMAN

TIMP-2, HUMAN

Background

Product Name: TIMP-2, HUMAN
CAS No.: 124861-55-8
Chemical Name: TIMP-2, HUMAN
Synonyms: DDC8;TIMP-2;CSC-21K;HUMAN TIMP-2;Hexapeptide-12;TIMP-2, HUMAN, R-DNA;Human Oligopeptide-20;TIMP-2, HUMAN, RECOMBINANT;Proteinase inhibitor TIMP2;TIMP-2, HUMAN。Hexapeptide-12
CBNumber: CB0438465
Formula Weight: 0
MOL File: Mol file

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TIMP-2, HUMAN Property

storage temp.: −20°C
form: buffered aqueous glycerol solution
color: white
biological source: human

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Safety

Hazard Codes: B,Xn,Xi
Risk Statements: 22-36/37/38-52/53
Safety Statements: 23-24/25-61-26
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRP3174
Product name: TIMP-2 human
Purity: recombinant, expressed in <I>E. coli</I>, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture
Packaging: 10 μg
Price: $362
Updated: 2025/07/31

Usbiological

Product number: 145277
Product name: TIMP2
Packaging: 100ug
Price: $490
Updated: 2021/12/16

Usbiological

Product number: 384634
Product name: TIMP-2
Packaging: 96Tests
Price: $669
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb529272
Product name: TIMP2
Packaging: 10μg
Price: $408
Updated: 2021/12/16

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TIMP-2, HUMAN Chemical Properties,Usage,Production

Biological Activity

Tissue inhibitor of metalloproteinase-2 (TIMP-2), like other protease inhibitors, functions as a key modulator of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through a matrix metalloproteinase (MMP)-independent mechanism inhibiting endothelial cell proliferation in vitro. It demonstrates anti-angiogenic activities in vivo. TIMP-2 is a target gene of the microRNA-miR-22.', 'TIMP-2 has a greater binding efficiency to MMP-2 than the other MMPs. Although TIMP-2 is an inhibitor of MMP-2, it is also required at low concentrations for the activation of MMP-2.

Background

TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases, the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently, the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors, and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.

TIMP-2, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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TIMP-2, HUMAN Suppliers

China 69 Germany 1 Japan 1 Switzerland 2 United Kingdom 1 United States 6 Global 80

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View Lastest Price from TIMP-2, HUMAN manufacturers

zhuzhou dingcheng meihei comestic co.,ltd

Product: Hexapeptide-12/HumanOligopeptide-20 124861-55-8
Price: US $30.00/Box
Min. Order: 1Box
Purity: 99.99%
Supply Ability: 10000000000
Release date: 2023-12-07

Zhuozhou Wenxi import and Export Co., Ltd

Product: TIMP-2.HUMAN 124861-55-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

124861-55-8, TIMP-2, HUMANRelated Search:

TIMP-1, human recombinant Palmitoyl Hexapeptide-14 Palmitoyl Hexapeptide-32 Acetyl Hexapeptide-20 Hexapeptide-27 Hexapeptide-32 Hexapeptide-47 Hexapeptide-52 phenylalanyl-glycyl-histidyl-statyl-alanyl-phenylalanine methyl ester phenylalanyl-glycyl-valyl-statyl-alanyl-phenylalanine methyl ester

TISSUE IHIBITOR OF METALLOPROTEINASE-2

TISSUE INHIBITOR OF METALLOPROTEINASE-2

TISSUE INHIBITOR OF METALLOPROTEINASE-2, HUMAN

TISSUE INHIBITOR OF METALLOPROTEINASE-2, HUMAN, R-DNA

TIMP-2

TIMP-2, HUMAN, R-DNA

TIMP-2, HUMAN, RECOMBINANT

TIMP-2, HUMAN RHEUMATOID SYNOVIAL FIBROBLAST

Tissue Inhibitor of Metalloproteinase-2 from mouse

HUMAN TIMP-2

Tissue Inhibitor of Metalloproteinase-2 from human fibroblasts

Hexapeptide-12

Proteinase inhibitor TIMP2

Tissue metalloprotease inhibitor 2

Tissue metalloproteinase inhibitor 2

CSC-21K

Human Oligopeptide-20

Recombinant Human TIMP-2 Protein, His Tag

TIMP-2, HUMAN。Hexapeptide-12

Hexapeptide-12/Human?Oligopeptide-20

CSC-21Ktissue inhibitor of metalloproteinase 2

DDC8

Tissue inhibitor of metalloproteinases 2

TIMP-2/TIMP2 Polyclonal Antibody

124861-55-8

Enzymes, Inhibitors, and Substrates

TIMPs

Matrix Metalloproteinases Products

Cell Signaling Enzymes

Biochemicals and Reagents

Application Index

BioChemical