2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID
- Product Name
- 2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID
- CAS No.
- 874784-14-2
- Chemical Name
- 2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID
- Synonyms
- BUTTPARK 51\07-22;2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID;2-amino-3-fluoro-5-bromobenzoic acid;Benzoic acid, 2-amino-5-bromo-3-fluoro-
- CBNumber
- CB0441939
- Molecular Formula
- C7H5BrFNO2
- Formula Weight
- 234.02
- MOL File
- Mol file
2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID Property
- Boiling point:
- 321.7±42.0 °C(Predicted)
- Density
- 1.877±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.21±0.10(Predicted)
- form
- very claggy powder
- color
- Off white to faint cream/beige
- InChI
- InChI=1S/C7H5BrFNO2/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2H,10H2,(H,11,12)
- InChIKey
- CLJZODGTJUYULK-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(Br)=CC(F)=C1N
Safety
- HS Code
- 2916310090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PC501399
- Product name
- 2-Amino-5-bromo-3-fluorobenzoicacid
- Packaging
- 250mg
- Price
- $73
- Updated
- 2021/12/16
- Product number
- PC501399
- Product name
- 2-Amino-5-bromo-3-fluorobenzoicacid
- Packaging
- 5g
- Price
- $348
- Updated
- 2021/12/16
- Product number
- PC501399
- Product name
- 2-Amino-5-bromo-3-fluorobenzoicacid
- Packaging
- 1g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- J50322
- Product name
- 2-Amino-5-bromo-3-fluorobenzoicacid
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 874784142
- Product name
- 2-Amino-5-bromo-3-fluorobenzoicacid
- Packaging
- 1g
- Price
- $208
- Updated
- 2021/12/16
2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
825-22-9
874784-14-2
Step 1: 2-Amino-3-fluorobenzoic acid (1.0 g, 6.45 mmol) was dissolved in N,N-dimethylformamide (DMF, 10 mL) at -10 °C. Subsequently, a solution of N-bromosuccinimide (NBS, 1.15 g, 6.45 mmol) in DMF (4 mL) was added dropwise to the above solution over 10 min. After the dropwise addition was completed, the reaction mixture was kept at -10°C and stirring was continued for 1 hour. Upon completion of the reaction, the reaction was quenched with aqueous sodium bisulfate (50 mL), at which point a large amount of solid precipitated. The solid product was collected by filtration and dried under vacuum to give 2-amino-5-bromo-3-fluorobenzoic acid (1.2 g, yield: 80%) as a yellow solid.
References
[1] Patent: WO2018/17490, 2018, A1. Location in patent: Paragraph 0153; 0154
[2] Patent: WO2015/200534, A2. Location in patent: Paragraph 00535
[2] Patent: , 2015, . Location in patent: Paragraph 00535
[4] Patent: WO2017/158388, 2017, A1. Location in patent: Page/Page column 212
[5] Patent: WO2014/11900, 2014, A2. Location in patent: Page/Page column 77
2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID Suppliers
- Tel
- 15088289376
- 248775804@qq.com
- Country
- China
- ProdList
- 4901
- Advantage
- 58
- Tel
- 18626188356
- Fax
- QQ926069669
- 1058187422@qq.com
- Country
- China
- ProdList
- 511
- Advantage
- 58
- Tel
- 021-50795510 4000665055
- marketing@accelachem.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 0535-6385396
- Fax
- +86 (535) 638-9971
- info@carbottpharm.com
- Country
- China
- ProdList
- 972
- Advantage
- 56
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39999
- Advantage
- 60
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5917
- Advantage
- 50
- Tel
- 17663603912
- Fax
- +86-536- 8637276
- 2710256076@qq.com
- Country
- China
- ProdList
- 195
- Advantage
- 56
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 5397
- Advantage
- 58
- Tel
- 0512-0512-52358471 17715136450
- Fax
- 05125235 6881
- sales@shiyabiopharm.com
- Country
- China
- ProdList
- 12127
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 86249
- Advantage
- 60