Riluzole hydrochloride

Product Name: Riluzole hydrochloride
CAS No.: 850608-87-6
Chemical Name: Riluzole hydrochloride
Synonyms: RILUZOLE HCL;RILUZOLE HYDROCHLORIDE;2-AMINO-6-TRIFLUOROMETHOXYBENZOTHIAZOLE HYDROCHLORIDE;6-(Trifluoromethoxy)benzo[d]thiazol-2-amine hydrochloride
CBNumber: CB0442491
Molecular Formula: C8H6ClF3N2OS
Formula Weight: 270.66
MOL File: Mol file

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Riluzole hydrochloride Property

storage temp.: Store at -20°C
solubility: DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2)(1:20): 0.04 mg/mL; Water: Soluble
form: A solid
color: White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14577
Product name: Riluzole (hydrochloride)
Purity: ≥99%
Packaging: 10mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 14577
Product name: Riluzole (hydrochloride)
Purity: ≥99%
Packaging: 50mg
Price: $169
Updated: 2024/03/01

Tocris

Product number: 0768
Product name: Riluzolehydrochloride
Purity: ≥98%(HPLC)
Packaging: 25
Price: $106
Updated: 2021/12/16

Usbiological

Product number: 256455
Product name: Riluzole hydrochloride
Packaging: 25mg
Price: $353
Updated: 2021/12/16

TRC

Product number: R510030
Product name: RiluzoleHydrochloride
Packaging: 250mg
Price: $580
Updated: 2021/12/16

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Riluzole hydrochloride Chemical Properties,Usage,Production

Description

Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na⁺ channels (ED₅₀ = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED₅₀ value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED₅₀ value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.

Uses

Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Riluzole has been explored as a therapeutic for slowing disease progression of amyotrophic lateral sclerosis.

Uses

Riluzole is a glutamate release inhibitor. It also induces caspase-dependent apoptosis and suppress cell proliferation in human heptocellular carcinoma. Riluzole is a neuroprotective and a anticancer agent.

storage

Room temperature

Riluzole hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Riluzole hydrochloride Suppliers

China 27 United Kingdom 2 United States 6 USA 1 Global 36

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
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Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
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Country: China
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Advantage: 55

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
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Country: China
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Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
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Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
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Country: China
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Fan De(Beijing) Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
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Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30240
Advantage: 58

850608-87-6, Riluzole hydrochlorideRelated Search:

6-TRIFLUOROMETHOXYBENZOTHIAZOLE Riluzole

2-AMINO-6-TRIFLUOROMETHOXYBENZOTHIAZOLE HYDROCHLORIDE

RILUZOLE HCL

RILUZOLE HYDROCHLORIDE

6-(Trifluoromethoxy)benzo[d]thiazol-2-amine hydrochloride

850608-87-6