Riluzole hydrochloride
- Product Name
- Riluzole hydrochloride
- CAS No.
- 850608-87-6
- Chemical Name
- Riluzole hydrochloride
- Synonyms
- RILUZOLE HCL;RILUZOLE HYDROCHLORIDE;2-AMINO-6-TRIFLUOROMETHOXYBENZOTHIAZOLE HYDROCHLORIDE;6-(Trifluoromethoxy)benzo[d]thiazol-2-amine hydrochloride
- CBNumber
- CB0442491
- Molecular Formula
- C8H6ClF3N2OS
- Formula Weight
- 270.66
- MOL File
- Mol file
Riluzole hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2)(1:20): 0.04 mg/mL; Water: Soluble
- form
- A solid
- color
- White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 14577
- Product name
- Riluzole (hydrochloride)
- Purity
- ≥99%
- Packaging
- 10mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 14577
- Product name
- Riluzole (hydrochloride)
- Purity
- ≥99%
- Packaging
- 50mg
- Price
- $169
- Updated
- 2024/03/01
- Product number
- 0768
- Product name
- Riluzolehydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 25
- Price
- $106
- Updated
- 2021/12/16
- Product number
- 256455
- Product name
- Riluzole hydrochloride
- Packaging
- 25mg
- Price
- $353
- Updated
- 2021/12/16
- Product number
- R510030
- Product name
- RiluzoleHydrochloride
- Packaging
- 250mg
- Price
- $580
- Updated
- 2021/12/16
Riluzole hydrochloride Chemical Properties,Usage,Production
Description
Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.
Uses
Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Riluzole has been explored as a therapeutic for slowing disease progression of amyotrophic lateral sclerosis.
Uses
Riluzole is a glutamate release inhibitor. It also induces caspase-dependent apoptosis and suppress cell proliferation in human heptocellular carcinoma. Riluzole is a neuroprotective and a anticancer agent.
storage
Room temperature
Riluzole hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Riluzole hydrochloride Suppliers
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