5,7-DIHYDROXYCOUMARIN
- Product Name
- 5,7-DIHYDROXYCOUMARIN
- CAS No.
- 2732-18-5
- Chemical Name
- 5,7-DIHYDROXYCOUMARIN
- Synonyms
- 5,7-DIHYDROXYCOUMARIN;5,7-dihydroxychromen-2-one;5,7-Dihydroxy-2H-chromen-2-one;5,7-dihydroxy-1-benzopyran-2-one;5,7-Dihydroxy-2H-1-benzopyran-2-one;5,7-Dihydroxycoumarin, 10 mM in DMSO;2H-1-Benzopyran-2-one, 5,7-dihydroxy-;Inhibitor,5,7-Dihydroxycoumarin,antibacterial,Bacterial,inhibit,5,7Dihydroxycoumarin,5,7 Dihydroxycoumarin,coumarin
- CBNumber
- CB0446015
- Molecular Formula
- C9H6O4
- Formula Weight
- 178.14
- MOL File
- 2732-18-5.mol
5,7-DIHYDROXYCOUMARIN Property
- Melting point:
- 280 °C
- Boiling point:
- 506.4±19.0 °C(Predicted)
- Density
- 1.563±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- Solid
- pka
- 7.18±0.20(Predicted)
- color
- Off-white to yellow
Safety
- HS Code
- 2932990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D457053
- Product name
- 5,7-Dihydroxy-2H-chromen-2-one
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-0103308
- Product name
- 5,7-Dihydroxycoumarin
- Purity
- 97.69%
- Packaging
- 1g
- Price
- $56
- Updated
- 2021/12/16
- Product number
- FD144414
- Product name
- 5,7-Dihydroxy-2H-chromen-2-one
- Packaging
- 250mg
- Price
- $62.5
- Updated
- 2021/12/16
- Product number
- FD144414
- Product name
- 5,7-Dihydroxy-2H-chromen-2-one
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- OR925694
- Product name
- 5,7-Dihydroxycoumarin
- Purity
- 95%
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
5,7-DIHYDROXYCOUMARIN Chemical Properties,Usage,Production
Uses
5,7-Dihydroxy-2H-chromen-2-one can be used to prepare UV-?responsive coumarin controlled release and self-?repairing antifouling paint.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 41, p. 4542, 1998 DOI: 10.1021/jm981032o
Journal of Heterocyclic Chemistry, 2, p. 91, 1965 DOI: 10.1002/jhet.5570020116
Synthesis
108-73-6
471-25-0
2732-18-5
The general procedure for the synthesis of 5,7-dihydroxy-2H-benzopyran-2-one from resorcinol and propargyl acid was as follows: a mixture of resorcinol (1.0 mmol), propargyl acid (1.1 mmol), and Yb(OTf)3 hydrate (0.1 mmol) was placed in an open reaction vessel in a microwave reaction unit and irradiated for 2 min at 200 W (80 °C) . The reaction process was monitored by thin layer chromatography (TLC) and the eluent was CH2Cl2/MeOH (99:1). Upon completion of the reaction, the crude product was diluted with ether (Et2O) and the suspension formed was filtered under vacuum to isolate the catalyst and the precipitate was washed with ether several times. The filtrate was washed twice sequentially with 5% NaHCO3 solution (10 mL), dried over anhydrous MgSO4 and evaporated to dryness under vacuum to afford the target product 5,7-dihydroxy-2H-benzopyran-2-one.
References
[1] Synlett, 1999, # 5, p. 608 - 610
[2] Tetrahedron Letters, 2016, vol. 57, # 26, p. 2939 - 2942
[3] Synthesis, 2011, # 8, p. 1283 - 1289
[4] Journal of Natural Medicines, 2017, vol. 71, # 4, p. 735 - 744
5,7-DIHYDROXYCOUMARIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5,7-DIHYDROXYCOUMARIN manufacturers
- Product
- 5,7-DIHYDROXYCOUMARIN 2732-18-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-01-08