4-HYDROXY MEPHENYTOIN

Product Name: 4-HYDROXY MEPHENYTOIN
CAS No.: 61837-65-8
Chemical Name: 4-HYDROXY MEPHENYTOIN
Synonyms: 4'-Hydroxymephenitoyn;4-HYDROXY MEPHENYTOIN;Mephenytoin Impurity 1;Mephenytoin Impurity 4;(+/-) -HYDROXYMEPHENYTOIN;(+/-)-4-HYDROXYMEPHENYTOIN;( /-)-4-Hydroxy Mephenytoin;4-HydroxyMephenytoin >=98% (HPLC);5-Ethyl-5-(4-hydroxyphenyl)-3-Methyl-;5-Ethyl-3-methyl-5-(4-hydroxyphenyl)hydantoin
CBNumber: CB5319831
Molecular Formula: C12H14N2O3
Formula Weight: 234.25
MOL File: 61837-65-8.mol

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4-HYDROXY MEPHENYTOIN Property

Melting point:: 153-154 °C
Density: 1.249±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >5mg/mL
pka: 8.31±0.70(Predicted)
form: Solid
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: UC126
Product name: 4-Hydroxymephenytoin
Packaging: 5mg
Price: $663
Updated: 2024/03/01

Sigma-Aldrich

Product number: H146
Product name: 4-Hydroxymephenytoin
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $323
Updated: 2024/03/01

Cayman Chemical

Product number: 16124
Product name: (±)4-Hydroxymephenytoin
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 16124
Product name: (±)4-Hydroxymephenytoin
Purity: ≥98%
Packaging: 10mg
Price: $145
Updated: 2024/03/01

Sigma-Aldrich

Product number: UC126
Product name: 4-Hydroxymephenytoin
Packaging: 10mg
Price: $1190
Updated: 2024/03/01

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4-HYDROXY MEPHENYTOIN Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

CYP2C19 metabolite of Mephenytoin

Uses

Pharmacological activity investigating:• ;The drug effects on metabolization1• ;In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3

Uses

Pharmacological activity investigating:

The drug effects on metabolization
In vitro cytochrome P450 activity in microsomes

Analyte for electron-capture gas chromatography procedures

Definition

ChEBI: Hydroxymephenytoin is an imidazolidine-2,4-dione.

General Description

CYP2C19 metabolite of mephenytoin.

Biochem/physiol Actions

4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized.

4-HYDROXY MEPHENYTOIN Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXY MEPHENYTOIN Suppliers

Canada 3 China 63 France 1 Germany 2 India 2 Switzerland 1 Ukraine 1 United Kingdom 4 United States 21 Global 98

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61837-65-8, 4-HYDROXY MEPHENYTOINRelated Search:

7-Hydroxycoumarin 7,8-Dihydroxycoumarin Warfarin 4-Hydroxycoumarin Scopoletin 4-HYDROXY MEPHENYTOIN-D3 Esculetin 5-Ethyl-5-methylhydantoin 5-METHYL-5-PHENYLHYDANTOIN 5-Phenylhydantoin 4-Hydroxyphenyl hydantoin 2-PHENYLBUTYRYLUREA Brodifacoum Bromadiolone 8-ACETYL DIMETHOXYCOUMARIN Dihydrocoumarin 5-(4-HYDROXYPHENYL)HYDANTOIN (R)-(-)-MEPHENYTOIN

(+/-) -HYDROXYMEPHENYTOIN

5-Ethyl-5-(4-hydroxyphenyl)-3-Methyl-

(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin, (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione

4-Hydroxy-5-ethyl-3-methyl-5-phenylimidazolidin-2-one

4'-Hydroxymephenitoyn

5-(p-Hydroxyphenyl)-3-methyl-5-ethyl-imidazolidine-2,4-dione

5-Ethyl-3-methyl-5-(4-hydroxyphenyl)hydantoin

5-Ethyl-3-methyl-5-(4-hydroxyphenyl)imidazolidine-2,4-dione

5-ethyl-5-(4-hydroxyphenyl)-3-MethyliMidazolidine-2,4-dione

4-HydroxyMephenytoin >=98% (HPLC)

(+/-)-5-ETHYL-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN

(+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN

(+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLIMIDIDAZOLIDINE-2,4-DIONE

(+/-)-4-HYDROXYMEPHENYTOIN

4-HYDROXY MEPHENYTOIN

5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione

Mephenytoin Impurity 1

2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-

( /-)-4-Hydroxy Mephenytoin

Mephenytoin Impurity 4

61837-65-8

Heterocyclic Building Blocks

Imidazolines/Imidazolidines

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Imidazolines/Imidazolidines

Metabolites

Building Blocks

Heterocycles

Hydantoins & Derivatives

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals