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4-HYDROXY MEPHENYTOIN

Product Name
4-HYDROXY MEPHENYTOIN
CAS No.
61837-65-8
Chemical Name
4-HYDROXY MEPHENYTOIN
Synonyms
4'-Hydroxymephenitoyn;4-HYDROXY MEPHENYTOIN;Mephenytoin Impurity 1;Mephenytoin Impurity 4;(±)4-Hydroxymephenytoin;(+/-) -HYDROXYMEPHENYTOIN;(+/-)-4-HYDROXYMEPHENYTOIN;( /-)-4-Hydroxy Mephenytoin;4-HydroxyMephenytoin >=98% (HPLC);4-Hydroxymephenytoin, 10 mM in DMSO
CBNumber
CB5319831
Molecular Formula
C12H14N2O3
Formula Weight
234.25
MOL File
61837-65-8.mol
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4-HYDROXY MEPHENYTOIN Property

Melting point:
153-154 °C
Density 
1.249±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >5mg/mL
pka
8.31±0.70(Predicted)
form 
Solid
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
UC126
Product name
4-Hydroxymephenytoin
Packaging
5mg
Price
$647.9
Updated
2025/07/31
Sigma-Aldrich
Product number
H146
Product name
4-Hydroxymephenytoin
Purity
≥98% (HPLC)
Packaging
5mg
Price
$316.35
Updated
2025/07/31
Cayman Chemical
Product number
16124
Product name
(±)4-Hydroxymephenytoin
Purity
≥98%
Packaging
5mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
16124
Product name
(±)4-Hydroxymephenytoin
Purity
≥98%
Packaging
10mg
Price
$145
Updated
2024/03/01
Sigma-Aldrich
Product number
UC126
Product name
4-Hydroxymephenytoin
Packaging
10mg
Price
$1220
Updated
2025/07/31
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4-HYDROXY MEPHENYTOIN Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

CYP2C19 metabolite of Mephenytoin

Uses

Pharmacological activity investigating:• ;The drug effects on metabolization1• ;In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3

Uses

Pharmacological activity investigating:

  • The drug effects on metabolization
  • In vitro cytochrome P450 activity in microsomes

Analyte for electron-capture gas chromatography procedures

Definition

ChEBI: Hydroxymephenytoin is an imidazolidine-2,4-dione.

General Description

CYP2C19 metabolite of mephenytoin.

Biochem/physiol Actions

4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized.

4-HYDROXY MEPHENYTOIN Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXY MEPHENYTOIN Suppliers

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61837-65-8, 4-HYDROXY MEPHENYTOINRelated Search:

7-Hydroxycoumarin 7,8-Dihydroxycoumarin Warfarin 4-Hydroxycoumarin Scopoletin 4-HYDROXY MEPHENYTOIN-D3 Esculetin 5-Ethyl-5-methylhydantoin 5-METHYL-5-PHENYLHYDANTOIN 5-Phenylhydantoin 4-Hydroxyphenyl hydantoin 2-PHENYLBUTYRYLUREA Brodifacoum Bromadiolone 8-ACETYL DIMETHOXYCOUMARIN Dihydrocoumarin 5-(4-HYDROXYPHENYL)HYDANTOIN (R)-(-)-MEPHENYTOIN

  • (+/-) -HYDROXYMEPHENYTOIN
  • 5-Ethyl-5-(4-hydroxyphenyl)-3-Methyl-
  • (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin, (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione
  • 4-Hydroxy-5-ethyl-3-methyl-5-phenylimidazolidin-2-one
  • 4'-Hydroxymephenitoyn
  • 5-(p-Hydroxyphenyl)-3-methyl-5-ethyl-imidazolidine-2,4-dione
  • 5-Ethyl-3-methyl-5-(4-hydroxyphenyl)hydantoin
  • 5-Ethyl-3-methyl-5-(4-hydroxyphenyl)imidazolidine-2,4-dione
  • 5-ethyl-5-(4-hydroxyphenyl)-3-MethyliMidazolidine-2,4-dione
  • 4-HydroxyMephenytoin >=98% (HPLC)
  • (+/-)-5-ETHYL-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN
  • (+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN
  • (+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLIMIDIDAZOLIDINE-2,4-DIONE
  • (+/-)-4-HYDROXYMEPHENYTOIN
  • 4-HYDROXY MEPHENYTOIN
  • 5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione
  • Mephenytoin Impurity 1
  • 2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-
  • ( /-)-4-Hydroxy Mephenytoin
  • Mephenytoin Impurity 4
  • 4-Hydroxymephenytoin, 10 mM in DMSO
  • (±)4-Hydroxymephenytoin
  • 61837-65-8
  • Heterocyclic Building Blocks
  • Imidazolines/Imidazolidines
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Imidazolines/Imidazolidines
  • Metabolites
  • Building Blocks
  • Heterocycles
  • Hydantoins & Derivatives
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals