ChemicalBook > CAS DataBase List > 7-Hydroxycoumarin

7-Hydroxycoumarin

Product Name
7-Hydroxycoumarin
CAS No.
93-35-6
Chemical Name
7-Hydroxycoumarin
Synonyms
UMBELLIFERONE;7-Hydroxycoumarine;Z-LIGUSTILIDE;SKIMMETIN;7-Hydroxy-2H-chromen-2-one;UMBELLIFERON;Dichrin A;7 HC;HYDRANGIN;Hydramgin
CBNumber
CB1854673
Molecular Formula
C9H6O3
Formula Weight
162.14
MOL File
93-35-6.mol
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7-Hydroxycoumarin Property

Melting point:
230 °C (dec.)(lit.)
Boiling point:
248.82°C (rough estimate)
Density 
1.2599 (rough estimate)
refractive index 
1.5380 (estimate)
storage temp. 
2-8°C
solubility 
dioxane: soluble
form 
Powder and Agglomerate
pka
7.11(at 25℃)
color 
Off-white to beige-brownish
PH Range
Non/ uorescence (6.5) to blue / uorescence (8.0)
Odor
develops odor of coumarin on heating
Water Solubility 
1 g/100 mL (100 ºC)
λmax
320nm
Merck 
14,9847
BRN 
127683
Major Application
Fluorescent brighteners, fungicides, cosmetics, antitrypanosomal, antileishmanial activities, antifungal, antibacterial, antiinflammatory, antiHIV, detection of microorganisms, treatment of impaired neurotransmission disorders, Alzheimer’s disease, vascular and lymphatic edema cancer, early diagnosis of stroke, dental material, drug-coated coronary stent system
InChIKey
ORHBXUUXSCNDEV-UHFFFAOYSA-N
LogP
1.580 (est)
CAS DataBase Reference
93-35-6(CAS DataBase Reference)
NIST Chemistry Reference
7-Hydroxycoumarin(93-35-6)
EPA Substance Registry System
Umbelliferone (93-35-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
GN6820000
HS Code 
29322980
Toxicity
LD50 intravenous in mouse: 450mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
93979
Product name
Umbelliferone
Purity
suitable for fluorescence indicator, ≥98.0% (HPLC)
Packaging
25g
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
54826
Product name
Umbelliferone
Purity
analytical standard
Packaging
50mg
Price
$140
Updated
2024/03/01
TCI Chemical
Product number
H0236
Product name
Umbelliferone
Purity
>98.0%(GC)
Packaging
5g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
H0236
Product name
Umbelliferone
Purity
>98.0%(GC)
Packaging
25g
Price
$60
Updated
2024/03/01
Alfa Aesar
Product number
L04082
Product name
7-Hydroxycoumarin, 98%
Packaging
25g
Price
$68.7
Updated
2024/03/01
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7-Hydroxycoumarin Chemical Properties,Usage,Production

Chemical Properties

Light Brownish Powder

Uses

A metabolite of Coumarin. The aglucon of skimmin. Present in many plants

Uses

antifungal, phytoalexin

Uses

7-Hydroxycoumarin is used as an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe. It is used as a sunscreen agent, and an optical brightener for textiles. It has also been used as a gain medium for dye lasers.

Uses

In sunscreen lotions and creams; as intracellular and pH sensitive fluorescent indicator and blood-brain barrier probe.

Definition

ChEBI: A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.

General Description

Umbelliferone is a naturally occurring coumarin, present in a variety of medicinal plants from the Apiaceae (Umbelliferae) family and also in plants from other families such as mouse-ear hawkweed.

Purification Methods

It crystallises from water (m 232-232.2o) or EtOH (m 232o). It sublimes at 160o/0.001mm. Fluorescence: Em max 452nm/Exc 325nm in 50% EtOH. [Beilstein 18 H 27, 18 I 306, 18 II 16, 18 III/IV 294, 18/1 V 386.]

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7-Hydroxycoumarin Suppliers

Inner Mongolia Yida Chemical Technology Co., Ltd.
Tel
18967392038
Email
67247734@qq.com
Country
China
ProdList
74
Advantage
58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18068193575
Fax
QQ1907456386
Email
sales11@btcpharm.com
Country
China
ProdList
1333
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
Advantage
62
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View Lastest Price from 7-Hydroxycoumarin manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
7-Hydroxycoumarin 93-35-6
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-21
hebei hongtan Biotechnology Co., Ltd
Product
7-Hydroxycoumarin 93-35-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-05-13
Hebei Weibang Biotechnology Co., Ltd
Product
7-Hydroxycoumarin 93-35-6
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-29

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