ChemicalBook > CAS DataBase List > 7-Ethoxycoumarin

7-Ethoxycoumarin

Product Name
7-Ethoxycoumarin
CAS No.
31005-02-4
Chemical Name
7-Ethoxycoumarin
Synonyms
ETHOXYCOUMARIN;7-ETHOXYCOUMARIN;ETHOXYCOUMARIN, 7-;Ethylumbelliferone;Coumarin, 7-ethoxy-;7-Ethoxycoumarin>7-Ethoxycoumarin ,99%;7-ethoxychromen-2-one;ETHOXYCOUMARIN, 7-(RG);7-O-Ethylumbelliferone
CBNumber
CB4357665
Molecular Formula
C11H10O3
Formula Weight
190.2
MOL File
31005-02-4.mol
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7-Ethoxycoumarin Property

Melting point:
88-90 °C (lit.)
Boiling point:
265.69°C (rough estimate)
Density 
1.1803 (rough estimate)
refractive index 
1.4260 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Pale Brown
Water Solubility 
Soluble in hot methanol (very faint turbidity), 95% ethanol (50 mg/ml), DMF, and DMSO. Insoluble in water.
BRN 
146200
LogP
2.310 (est)
CAS DataBase Reference
31005-02-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E1379
Product name
7-Ethoxycoumarin
Packaging
25mg
Price
$18.18
Updated
2024/03/01
Sigma-Aldrich
Product number
E1379
Product name
7-Ethoxycoumarin
Packaging
1g
Price
$334
Updated
2024/03/01
TCI Chemical
Product number
E0538
Product name
7-Ethoxycoumarin
Purity
>97.0%(GC)
Packaging
5g
Price
$162
Updated
2024/03/01
TCI Chemical
Product number
E0538
Product name
7-Ethoxycoumarin
Purity
>97.0%(GC)
Packaging
25g
Price
$486
Updated
2024/03/01
Alfa Aesar
Product number
L14116
Product name
7-Ethoxycoumarin, 99%
Packaging
100mg
Price
$42.65
Updated
2024/03/01
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7-Ethoxycoumarin Chemical Properties,Usage,Production

Chemical Properties

BEIGE CRYSTALLINE POWDER

Uses

7-Ethoxycoumarin is a substrate for CYP2B6 used in fluorometric assays of microsomal monooxygenase activity.

Uses

7-Ethoxycoumarin is commonly used for metabolism studies, including hepatocyte studies, liver perfusion techniques and cytochrome P450 studies.
7-Ethoxycoumarin has been used to study the functional activity of recombinant P450. ) It has also been used as an internal standard for in vitro S-warfarin 7-hydroxylation and high performance liquid chromatography (HPLC) analysis.

Definition

ChEBI: 7-ethoxycoumarin is a member of the class of coumarins that is umbelliferone in which the hydroxy group at position 7 is replaced by an ethoxy group. It is an aromatic ether and a member of coumarins. It derives from an umbelliferone.

Biochem/physiol Actions

7-Ethoxycoumarin is a cytochrome P450 substrate.

Metabolism

7-Ethoxycoumarin is metabolized by many cytochrome P450 enzymes active in foreign compound metabolism and has been used as a prototypic substrate to monitor P450 (P450) activity in both hepatic and extrahepatic tissues.
The in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.
Use of 7-Ethoxycoumarin to Monitor Multiple Enzymes in the Human CYP1, CYP2, and CYP3 Families

7-Ethoxycoumarin Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Ethoxycoumarin Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
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62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
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Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
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Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18736
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57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
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View Lastest Price from 7-Ethoxycoumarin manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
7-Ethoxycoumarin 31005-02-4
Price
US $40.00-3.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-12
Hebei Guanlang Biotechnology Co., Ltd.
Product
7-Ethoxycoumarin 31005-02-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-17
Dideu Industries Group Limited
Product
7-ETHOXYCOUMARIN 31005-02-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-29

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  • Fluorescent Enzyme Substrates
  • Fluorescent Probes, Labels, Particles and Stains
  • Fluorescent Enzyme Substrates for Spectroscopy
  • Detection
  • Alphabetical
  • Biochemicals and Reagents
  • BioChemical
  • Building block
  • Coumarin
  • Aromatics Compounds
  • Aromatics