ChemicalBook > CAS DataBase List > 7-Ethoxycoumarin

7-Ethoxycoumarin

Product Name: 7-Ethoxycoumarin
CAS No.: 31005-02-4
Chemical Name: 7-Ethoxycoumarin
Synonyms: ETHOXYCOUMARIN;7-ETHOXYCOUMARIN;ETHOXYCOUMARIN, 7-;Ethylumbelliferone;Coumarin, 7-ethoxy-;7-Ethoxycoumarin>7-Ethoxycoumarin ,99%;7-ethoxychromen-2-one;ETHOXYCOUMARIN, 7-(RG);7-O-Ethylumbelliferone
CBNumber: CB4357665
Molecular Formula: C11H10O3
Formula Weight: 190.2
MOL File: 31005-02-4.mol

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7-Ethoxycoumarin Property

Melting point:: 88-90 °C (lit.)
Boiling point:: 265.69°C (rough estimate)
Density: 1.1803 (rough estimate)
refractive index: 1.4260 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
color: Off-White to Pale Brown
Water Solubility: Soluble in hot methanol (very faint turbidity), 95% ethanol (50 mg/ml), DMF, and DMSO. Insoluble in water.
BRN: 146200
LogP: 2.310 (est)
CAS DataBase Reference: 31005-02-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Safety Statements: 22-24/25
WGK Germany: 3
F: 8
Hazard Note: Irritant
TSCA: Yes
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E1379
Product name: 7-Ethoxycoumarin
Packaging: 25mg
Price: $29.64
Updated: 2025/07/31

Sigma-Aldrich

Product number: E1379
Product name: 7-Ethoxycoumarin
Packaging: 1g
Price: $343
Updated: 2025/07/31

Sigma-Aldrich

Product number: 41577
Product name: 7-Ethoxycoumarin
Purity: analytical standard
Packaging: 10 mg
Price: $101
Updated: 2025/07/31

TCI Chemical

Product number: E0538
Product name: 7-Ethoxycoumarin
Purity: >97.0%(GC)
Packaging: 5g
Price: $146
Updated: 2025/07/31

TCI Chemical

Product number: E0538
Product name: 7-Ethoxycoumarin
Purity: >97.0%(GC)
Packaging: 25g
Price: $437
Updated: 2025/07/31

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7-Ethoxycoumarin Chemical Properties,Usage,Production

Description

7-Ethoxycoumarin is oneof the general substrates for liver cytochrome P450 enzymes, and it is known that CYP1A1,1A2, and 2B1, drug inducedtypes (b-naphthoflavone, isosafrole, and phenobarbital,re-spectively, in rat liver) are mainly responsible for the ECDE activity in the liver.

Chemical Properties

BEIGE CRYSTALLINE POWDER

Uses

7-Ethoxycoumarin is a substrate for CYP2B6 used in fluorometric assays of microsomal monooxygenase activity.

Uses

7-Ethoxycoumarin is commonly used for metabolism studies, including hepatocyte studies, liver perfusion techniques and cytochrome P450 studies.
7-Ethoxycoumarin has been used to study the functional activity of recombinant P450. ) It has also been used as an internal standard for in vitro S-warfarin 7-hydroxylation and high performance liquid chromatography (HPLC) analysis.

Definition

ChEBI: 7-ethoxycoumarin is a member of the class of coumarins that is umbelliferone in which the hydroxy group at position 7 is replaced by an ethoxy group. It is an aromatic ether and a member of coumarins. It derives from an umbelliferone.

Biochem/physiol Actions

7-Ethoxycoumarin is a cytochrome P450 substrate.

Metabolism

7-Ethoxycoumarin is metabolized by many cytochrome P450 enzymes active in foreign compound metabolism and has been used as a prototypic substrate to monitor P450 (P450) activity in both hepatic and extrahepatic tissues.
The in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.
Use of 7-Ethoxycoumarin to Monitor Multiple Enzymes in the Human CYP1, CYP2, and CYP3 Families

7-Ethoxycoumarin Preparation Products And Raw materials

Raw materials

7-Hydroxycoumarin Acetone Potassium carbonate Bromoethane

Preparation Products

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7-Ethoxycoumarin Suppliers

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View Lastest Price from 7-Ethoxycoumarin manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 7-Ethoxycoumarin 31005-02-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

Hebei Yanxi Chemical Co., Ltd.

Product: 7-Ethoxycoumarin 31005-02-4
Price: US $40.00-3.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-09-12

Dideu Industries Group Limited

Product: 7-ETHOXYCOUMARIN 31005-02-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-29

31005-02-4, 7-EthoxycoumarinRelated Search:

4-Methylumbelliferyl-beta-D-glucuronide 7-HYDROXYCOUMARIN GLUCOSIDE 7-Ethoxycoumarin ESCULETIN DIBENZYL ETHER AFLATOXIN G1 4-Methylumbelliferyl-beta-D-glucopyranoside 7-Acetoxy-4-methylcoumarin 4-METHYL-7-ETHOXYCOUMARIN,METHYL-7-ETHOXYCOUMARIN, 4-(SG),METHYL-7-ETHOXYCOUMARIN, 4- 4-ETHOXYCOUMARIN,ETHOXYCOUMARIN, 4-,4-Ethoxycoumarin,98%,ETHOXYCOUMARIN, 4-(RG),4-ETHOXYCOUMARIN 98% 6,7-DIACETOXY-4-METHYLCOUMARIN ETHYL 7-ACETOXYCOUMARIN-3-CARBOXYLATE 6,7-DIETHOXY-4-METHYLCOUMARIN 3-ACETYL-7-[BETA-D-GLUCOPYRANOSYLOXY]-COUMARIN 4-METHYLUMBELLIFERYL-N,N',N''-TRIACETYL-BETA-CHITOTRIOSIDE (4-Methylumbelliferyl)-α-L-iduronide cyclohexylammonium salt 4-Methylumbelliferyl 2-Amino-2-deoxy-a-D-glucopyranoside 7-(CARBOXYMETHOXY)-4-METHYLCOUMARIN 3-CARBOXYUMBELLIFERYL ACETATE

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7-Ethoxycoumarin, 10 mM in DMSO

31005-02-4

Fluorescent Enzyme Substrates

Fluorescent Probes, Labels, Particles and Stains

Fluorescent Enzyme Substrates for Spectroscopy

Detection

Alphabetical

Biochemicals and Reagents

BioChemical

Building block

Coumarin

Aromatics Compounds

Aromatics