7-Hydroxycoumarin

Product Name: 7-Hydroxycoumarin
CAS No.: 93-35-6
Chemical Name: 7-Hydroxycoumarin
Synonyms: UMBELLIFERONE;7-Hydroxycoumarine;Z-LIGUSTILIDE;SKIMMETIN;7-Hydroxy-2H-chromen-2-one;UMBELLIFERON;Dichrin A;7 HC;HYDRANGIN;Hydramgin
CBNumber: CB1854673
Molecular Formula: C9H6O3
Formula Weight: 162.14
MOL File: 93-35-6.mol

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7-Hydroxycoumarin Property

Melting point:: 230 °C (dec.)(lit.)
Boiling point:: 248.82°C (rough estimate)
Density: 1.2599 (rough estimate)
refractive index: 1.5380 (estimate)
storage temp.: 2-8°C
solubility: dioxane: soluble
pka: 7.11(at 25℃)
form: Powder and Agglomerate
color: Off-white to beige-brownish
PH Range: Non/ uorescence (6.5) to blue / uorescence (8.0)
Odor: develops odor of coumarin on heating
Water Solubility: 1 g/100 mL (100 ºC)
λmax: 320nm
Merck: 14,9847
BRN: 127683
Major Application: Fluorescent brighteners, fungicides, cosmetics, antitrypanosomal, antileishmanial activities, antifungal, antibacterial, antiinflammatory, antiHIV, detection of microorganisms, treatment of impaired neurotransmission disorders, Alzheimer’s disease, vascular and lymphatic edema cancer, early diagnosis of stroke, dental material, drug-coated coronary stent system
InChIKey: ORHBXUUXSCNDEV-UHFFFAOYSA-N
LogP: 1.580 (est)
CAS DataBase Reference: 93-35-6(CAS DataBase Reference)
NIST Chemistry Reference: 7-Hydroxycoumarin(93-35-6)
EPA Substance Registry System: Umbelliferone (93-35-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: GN6820000
HS Code: 29322980
Toxicity: LD50 intravenous in mouse: 450mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 93979
Product name: Umbelliferone
Purity: suitable for fluorescence indicator, ≥98.0% (HPLC)
Packaging: 25g
Price: $111
Updated: 2024/03/01

Sigma-Aldrich

Product number: 54826
Product name: Umbelliferone
Purity: analytical standard
Packaging: 50mg
Price: $140
Updated: 2024/03/01

TCI Chemical

Product number: H0236
Product name: Umbelliferone
Purity: >98.0%(GC)
Packaging: 5g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: H0236
Product name: Umbelliferone
Purity: >98.0%(GC)
Packaging: 25g
Price: $60
Updated: 2024/03/01

Alfa Aesar

Product number: L04082
Product name: 7-Hydroxycoumarin, 98%
Packaging: 25g
Price: $68.7
Updated: 2024/03/01

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7-Hydroxycoumarin Chemical Properties,Usage,Production

Chemical Properties

Light Brownish Powder

Uses

A metabolite of Coumarin. The aglucon of skimmin. Present in many plants

Uses

antifungal, phytoalexin

Uses

7-Hydroxycoumarin is used as an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe. It is used as a sunscreen agent, and an optical brightener for textiles. It has also been used as a gain medium for dye lasers.

Uses

In sunscreen lotions and creams; as intracellular and pH sensitive fluorescent indicator and blood-brain barrier probe.

Definition

ChEBI: A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.

General Description

Umbelliferone is a naturally occurring coumarin, present in a variety of medicinal plants from the Apiaceae (Umbelliferae) family and also in plants from other families such as mouse-ear hawkweed.

Purification Methods

It crystallises from water (m 232-232.2o) or EtOH (m 232o). It sublimes at 160o/0.001mm. Fluorescence: Em max 452nm/Exc 325nm in 50% EtOH. [Beilstein 18 H 27, 18 I 306, 18 II 16, 18 III/IV 294, 18/1 V 386.]

7-Hydroxycoumarin Preparation Products And Raw materials

Raw materials

2,4-Dihydroxyacetophenone

Preparation Products

[(2-OXO-2H-CHROMEN-7-YL)OXY]ACETIC ACID 8-ACETYL-6-HYDROXY-7-METHOXY-CHROMEN-2-ONE 7-ACETOXYCOUMARIN CHEMBRDG-BB 6088138 FRAXIDIN 7-Methoxycoumarin 7-Ethoxycoumarin 2-(2-OXO-2H-CHROMEN-7-YLOXY)-PROPIONIC ACID 8-ACETYL-7-HYDROXYCOUMARIN 8-ACETYL-7-METHOXYCOUMARIN XANTHOTOXOL 7-ALLYLOXYCOUMARIN

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View Lastest Price from 7-Hydroxycoumarin manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: 7-Hydroxycoumarin 93-35-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000kg
Release date: 2024-05-13

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 7-Hydroxycoumarin 93-35-6
Price: US $79.00-38.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-11-21

Hebei Weibang Biotechnology Co., Ltd

Product: 7-Hydroxycoumarin 93-35-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

93-35-6, 7-HydroxycoumarinRelated Search:

Coumarin Tetrahydro-4H-pyran-4-one Methylparaben 4-Hydroxybenzoic acid 4-Hydroxybenzaldehyde 2,2',4,4'-Tetrahydroxybenzophenone 4'-Hydroxyacetophenone 3,4-Dihydroxyacetophenone 4-Methoxyphenol CHLOROPHOSPHONAZO III Dihydrocoumarin Esculetin 6-Hydroxycoumarin DICUMAROL 4-HYDROXY MEPHENYTOIN 4-Methylumbelliferone 4-HYDROXYCOUMARIN, FOR FLUORESCENCE,4-Hydroxycoumarin99%,HydroxyCoumarin,4-HYDROXYCOUMARIN (98.0%),HYDROXYCOUMARIN, 4-(RG) 3-(α-acetonyl-2-furylmethyl)-4-hydroxycoumarin

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93-35-6

93-32-6

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